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Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride

CAS No.
60421-23-0
Chemical Name:
Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride
Synonyms
Nsc161119;AC5C-OMe HCl;cycloeucinemethyl ester HCL;Cycloleucine Methyl EsteroHCl;CYCLOLEUCINE METHYL ESTER HCL;Cycloeucine methyl ester hydrochloride;Cycloleucine Methyl Ester Hydrochloride;METHYL 1-AMINOCYCLOPENTYLCARBOXYLATE HCL;methyl 1-aminocyclopentanecarboxylate, HCl;Methyl-1-aminocyclopentanecarboxylate hydrochloride
CBNumber:
CB5201792
Molecular Formula:
C7H14ClNO2
Molecular Weight:
179.64
MDL Number:
MFCD03840364
MOL File:
60421-23-0.mol
MSDS File:
SDS
Last updated:2026-05-28 03:58:16

Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride Properties

Melting point 207-208 °C (decomp)
storage temp. Inert atmosphere,Room Temperature
form powder to crystal
color White to Almost white
InChI InChI=1S/C7H13NO2/c1-10-6(9)7(8)4-2-3-5-7/h2-5,8H2,1H3
InChIKey VLNNACMZTDZCFH-UHFFFAOYSA-N
SMILES C1(N)(CCCC1)C(=O)OC

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H319-H315-H335
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
HS Code  2902190000

Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical M2351 Methyl 1-Aminocyclopentanecarboxylate Hydrochloride >98.0%(T) 60421-23-0 1g $31 2026-04-30 Buy
TCI Chemical M2351 Methyl 1-Aminocyclopentanecarboxylate Hydrochloride >98.0%(T) 60421-23-0 5g $86 2026-04-30 Buy
AstaTech 64390 METHYL 1-AMINOCYCLOPENTYLCARBOXYLATE HCL 97% 60421-23-0 1G $24 2026-04-30 Buy
AstaTech 64390 METHYL 1-AMINOCYCLOPENTYLCARBOXYLATE HCL 97% 60421-23-0 5G $69 2026-04-30 Buy
AstaTech 64390 METHYL 1-AMINOCYCLOPENTYLCARBOXYLATE HCL 97% 60421-23-0 25G $210 2026-04-30 Buy
Product number Packaging Price Buy
M2351 1g $31 Buy
M2351 5g $86 Buy
64390 1G $24 Buy
64390 5G $69 Buy
64390 25G $210 Buy

Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride Chemical Properties,Uses,Production

Synthesis

Methanol

67-56-1

Cycloleucine

52-52-8

Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride

60421-23-0

1. cool a suspension of 1-aminocyclopentanecarboxylic acid (675 g, 5.23 mol, 1.0 eq.) in methanol (6.5 L) at -15 °C using an ice/methanol bath. 2. thionyl chloride (687 mL, 9.4 mol, 1.8 eq.) was slowly added dropwise with controlled titration rate to maintain reaction temperature. 3. after completion of the dropwise addition, the cooling device was removed and the reaction mixture was allowed to warm to room temperature and stirred overnight. 4. Upon completion of the reaction, the reaction mixture was concentrated under reduced pressure. 5. 5. The concentrated residue was treated with dichloromethane (1 L) and concentrated again under reduced pressure to give methyl 1-aminocyclopentanecarboxylate hydrochloride as a white solid (938 g, 100% yield). 6. The product was analyzed by 1H NMR. 6. The product was characterized by 1H NMR (CD3OD) and NMR (DMSO-d6) to confirm the correct structure. 7. The product obtained did not require further purification and could be used directly in the subsequent reaction steps.

References

[1] Patent: US6353006, 2002, B1. Location in patent: Page column 31
[2] Patent: WO2013/19091, 2013, A2. Location in patent: Paragraph 821-823
[3] Patent: US2014/206875, 2014, A1. Location in patent: Paragraph 0449-0451
[4] Patent: WO2003/87069, 2003, A2. Location in patent: Page/Page column 103-104
[5] Patent: WO2006/44775, 2006, A2. Location in patent: Page/Page column 35-36

67-56-1
52-52-8
60421-23-0
Synthesis of Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride from Methanol and Cycloleucine

Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride Preparation Products And Raw materials

Global( 170)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66

View Lastest Price from Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl 1-aminocyclopentanecarboxylate hydrochloride pictures 2026-08-25 Methyl 1-aminocyclopentanecarboxylate hydrochloride
60421-23-0
$1.10-9.90 1KG 99%min 100KG ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride pictures 2019-12-20 Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride
60421-23-0
$1.00 1KG 95%~99% 1ton Career Henan Chemical Co

Methyl 1-amino-1-cyclopentanecarboxylate hydrochloride Spectrum

METHYL 1-AMINOCYCLOPENTYLCARBOXYLATE HCL methyl 1-aminocyclopentanecarboxylate, HCl Cyclopentanecarboxylic acid, 1-amino-, methyl ester, hydrochloride Cycloeucine methyl ester hydrochloride Nsc161119 1-Amino-1-cyclopentanecarboxylic acid methyl ester hydrochloride cycloeucinemethyl ester HCL AC5C-OMe HCl 2-aMino-2-Methylcyclopentane-1-carboxylate hydrochloride Cycloleucine Methyl EsteroHCl methyl 1-aminocyclopentane-1-carboxylate hydrochloride 1-Aminocyclopentanecarboxylic acid methyl ester hydrochloride Methyl-1-aminocyclopentanecarboxylate hydrochloride METHYL1-AMINOCYCLOPENTANECARBOXYLATEHCL(CYCLOLEUCINEMETHYLESTERHCL) 1-Aminocyclopentane-1-carboxylic acid methyl ester hydrochloride Cycloleucine Methyl Ester.HCl CYCLOLEUCINE METHYL ESTER HCL METHYL 1-AMINO-1-CYCLOPENTANECARBOXYLATE HYDROCHLORIDE Methyl1-AminocyclopentanecarboxylateHydrochloride> Cycloleucine Methyl Ester Hydrochloride Cyclopentanecarboxylic acid, 1-amino-, methyl ester, hydrochloride (1:1) 1-amino-Cyclopentanecarboxylic acid methyl ester hydrochloride (1:1) 1-Aminocyclopentane-carboxylic acid methyl ester HCl 60421-23-0 Cycloalkanes