ChemicalBook >> CAS DataBase List >>2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 structure

CAS No.: 154554-41-3

Chemical Name:: 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158

Synonyms: CHM 1;NSC 656158;CHM-1 hydrate;CHM1, Antitumor agent;6-(2-Fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5H)-one;6-(2-Fluoro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-8-one;1,3-Dioxolo[4,5-g]quinolin-8(5H)-one, 6-(2-fluorophenyl)-;2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate;2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158;Inhibitor,microtubule-destabilizing,Cdc2,carcinoma,CHM1,NSC-656158,Microtubule/Tubulin,hepatocellular,NSC656158,antitumor,inhibit,CHM-1,CHM 1,antimitotic,NSC 656158

CBNumber:: CB52096271

Molecular Formula:: C16H10FNO3

Molecular Weight:: 283.25

MDL Number:: MFCD11114577

MOL File:: 154554-41-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-22 18:57:36

Request For Quotation

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 Properties

storage temp.	2-8°C
solubility	DMSO: ≥5mg/mL
form	solid
color	Off-white to light yellow
InChI	1S/C16H10FNO3.H2O/c17-11-4-2-1-3-9(11)12-6-14(19)10-5-15-16(21-8-20-15)7-13(10)18-12;/h1-7H,8H2,(H,18,19);1H2
InChIKey	KIAVGSCBJYDTIM-UHFFFAOYSA-N
SMILES	O.Fc1ccccc1C2=CC(=O)c3cc4OCOc4cc3N2
UNSPSC Code	12352202
NACRES	NA.77

SAFETY

Risk and Safety Statements

PPE	Eyeshields, Gloves, type N95 (US)
WGK Germany	3
Storage Class	11 - Combustible Solids

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 price More Price(25)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	27647	CHM-1 ≥98%	154554-41-3	1mg	$41	2026-04-30	Buy
Cayman Chemical	27647	CHM-1 ≥98%	154554-41-3	5mg	$128	2026-04-30	Buy
Cayman Chemical	27647	CHM-1 ≥98%	154554-41-3	10mg	$157	2026-04-30	Buy
Usbiological	254966	CHM 1 Asreported	154554-41-3	10mg	$423	2026-06-03	Buy
Usbiological	254966	CHM 1 Asreported	154554-41-3	50mg	$1103	2026-06-03	Buy

Product number	Packaging	Price	Buy
27647	1mg	$41	Buy
27647	5mg	$128	Buy
27647	10mg	$157	Buy
254966	10mg	$423	Buy
254966	50mg	$1103	Buy

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 Chemical Properties, Uses, Production

Uses

CHM-1 is a potent apoptosis inducer.

Biological Activity

CHM-1 possess antimitotic,antiangiogenic and antitumor activity. It is a potent and selective antitumor agent in human hepatocellular carcinoma. CHM-1 induces apoptosis, and it binds tubulin and inhibits tubulin polymerization.

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 synthesis

Synthesis of 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 from 6-Amino-3,4-methylenedioxyacetophenone

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 Preparation Products And Raw materials

Raw materials

N-(6-acetyl-2H-1,3-benzodioxol-5-yl)-2-fluorobenzamide

Preparation Products

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 Suppliers

Global Suppliers ( 42)

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
AdooQ BioScience, LLC	+1 (866) 930-6790	info@adooq.com	United States	2774	58
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8435	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9799	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11123	58
ShangHai ChuanQian Chemcial Technique Centre	15869524721	3525679403@qq.com	China	4565	58
Energy Chemical	400-0056266	marketing1@energy-chemical.com	China	44927	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8137	58

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
AdooQ BioScience, LLC	58
EMMX Biotechnology LLC	60
Shanghai EFE Biological Technology Co., Ltd.	58
BOC Sciences	58
TargetMol Chemicals Inc.	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
ShangHai ChuanQian Chemcial Technique Centre	58
Energy Chemical	58
MedBioPharmaceutical Technology Inc	58

View Latest Price from 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-22	CHM-1 154554-41-3	$33.00-120.00		99.83%	10g	TargetMol Chemicals Inc.

CHM-1
154554-41-3
$33.00-120.00
99.83%
TargetMol Chemicals Inc.

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 Spectrum

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158(154554-41-3)¹HNMR

154554-41-3 (2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158) Related Search:

Lunamarine 2-(4-Fluorophenyl)-7,8-diMethoxy-quinolin-4(1H)-one 2-(3-fluorophenyl)-5,6-dimethoxyquinolin-4(1H)-one 2-(3-Fluorophenyl)-5-hydroxy-6-Methoxy-4(1H)-quinolinone 2-(2-Fluorophenyl)-5-hydroxy-6-methoxyquinolin-4(1H)-one

GRAVEOLINE

1of2

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158 CHM-1 hydrate 6-(2-Fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5H)-one CHM 1 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate NSC 656158 6-(2-Fluoro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-8-one 1,3-Dioxolo[4,5-g]quinolin-8(5H)-one, 6-(2-fluorophenyl)- Inhibitor,microtubule-destabilizing,Cdc2,carcinoma,CHM1,NSC-656158,Microtubule/Tubulin,hepatocellular,NSC656158,antitumor,inhibit,CHM-1,CHM 1,antimitotic,NSC 656158 CHM1, Antitumor agent 154554-41-3