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ChemicalBook >> CAS DataBase List >> 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158

$27 - $1302.49
Product name: 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158
CAS: 154554-41-3
MF: C16H10FNO3
MW: 283.25
EINECS:
MDL Number:MFCD11114577
Synonyms:2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158;CHM-1 hydrate;6-(2-Fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5H)-one;CHM 1;2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate;NSC 656158;6-(2-Fluoro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-8-one;1,3-Dioxolo[4,5-g]quinolin-8(5H)-one, 6-(2-fluorophenyl)-

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Brand

aablocks
ACHEMBLOCK
American Custom Chemicals Corporation
ApexBio Technology
Cayman Chemical
ChemScene
TRC
Usbiological

Package

1mg
5mg
10mg
25mg
50mg
100mg

Manufactureraablocks
Product numberAA00AKO9
Product descriptionCHM-1
Packaging5mg
Price$47
Updated2026-05-28
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Manufactureraablocks
Product numberAA00AKO9
Product descriptionCHM-1
Packaging10mg
Price$65
Updated2026-05-28
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Manufactureraablocks
Product numberAA00AKO9
Product descriptionCHM-1
Packaging25mg
Price$116
Updated2026-05-28
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Manufactureraablocks
Product numberAA00AKO9
Product descriptionCHM-1
Packaging50mg
Price$154
Updated2026-05-28
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Manufactureraablocks
Product numberAA00AKO9
Product descriptionCHM-1
Packaging100mg
Price$221
Updated2026-05-28
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ManufacturerACHEMBLOCK
Product numberY227312
Product descriptionCHM-1 97.00%
Packaging25MG
Price$140
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberY227312
Product descriptionCHM-1 97.00%
Packaging100MG
Price$300
Updated2026-05-27
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberINB0001053
Product descriptionCHM-1 HYDRATE 95.00%
Packaging5MG
Price$770.56
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberINB0001053
Product descriptionCHM-1 HYDRATE 95.00%
Packaging25MG
Price$1302.49
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA4450
Product descriptionCHM 1
Packaging10mg
Price$277
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberA4450
Product descriptionCHM 1
Packaging50mg
Price$1095
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberA4450
Product descriptionCHM 1
Packaging5mg
Price$158
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberA4450
Product descriptionCHM 1
Packaging1mg
Price$58
Updated2026-05-06
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ManufacturerCayman Chemical
Product number27647
Product descriptionCHM-1 ≥98%
Packaging1mg
Price$41
Updated2026-04-30
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ManufacturerCayman Chemical
Product number27647
Product descriptionCHM-1 ≥98%
Packaging5mg
Price$128
Updated2026-04-30
Buy

ManufacturerCayman Chemical
Product number27647
Product descriptionCHM-1 ≥98%
Packaging10mg
Price$157
Updated2026-04-30
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00AKO9	CHM-1	5mg	$47	2026-05-28	Buy
aablocks	AA00AKO9	CHM-1	10mg	$65	2026-05-28	Buy
aablocks	AA00AKO9	CHM-1	25mg	$116	2026-05-28	Buy
aablocks	AA00AKO9	CHM-1	50mg	$154	2026-05-28	Buy
aablocks	AA00AKO9	CHM-1	100mg	$221	2026-05-28	Buy
ACHEMBLOCK	Y227312	CHM-1 97.00%	25MG	$140	2026-05-27	Buy
ACHEMBLOCK	Y227312	CHM-1 97.00%	100MG	$300	2026-05-27	Buy
American Custom Chemicals Corporation	INB0001053	CHM-1 HYDRATE 95.00%	5MG	$770.56	2021-12-16	Buy
American Custom Chemicals Corporation	INB0001053	CHM-1 HYDRATE 95.00%	25MG	$1302.49	2021-12-16	Buy
ApexBio Technology	A4450	CHM 1	10mg	$277	2026-05-06	Buy
ApexBio Technology	A4450	CHM 1	50mg	$1095	2026-05-06	Buy
ApexBio Technology	A4450	CHM 1	5mg	$158	2026-05-06	Buy
ApexBio Technology	A4450	CHM 1	1mg	$58	2026-05-06	Buy
Cayman Chemical	27647	CHM-1 ≥98%	1mg	$41	2026-04-30	Buy
Cayman Chemical	27647	CHM-1 ≥98%	5mg	$128	2026-04-30	Buy
Cayman Chemical	27647	CHM-1 ≥98%	10mg	$157	2026-04-30	Buy

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Properties

storage temp. :2-8°C
solubility :DMSO: ≥5mg/mL
form :solid
color :Off-white to light yellow
InChI :1S/C16H10FNO3.H2O/c17-11-4-2-1-3-9(11)12-6-14(19)10-5-15-16(21-8-20-15)7-13(10)18-12;/h1-7H,8H2,(H,18,19);1H2
InChIKey :KIAVGSCBJYDTIM-UHFFFAOYSA-N
SMILES :O.Fc1ccccc1C2=CC(=O)c3cc4OCOc4cc3N2

Safety Information

Symbol(GHS):

Signal word:

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Description

CHM-1 is a potent, selective antitumor agent in human hepatocellular carcinoma in vitro. CHM-1 induces apoptosis, and it binds tubulin and inhibits tubulin polymerization in vitro. Noted to cause cell cycle arrest at G₂/M phase by activation of Cdc kinase activity. Also, CHM-1 exhibits vascular targeting activity through upregulation of p53 and induction of death receptor (DR5)-mediated apoptosis in HUVEC cells. Furthermore reported to induce translocation of apoptosis inducing factor (AIF) from the mitochondria to nucleus.

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TargetMol Chemicals Inc.

$33.00
CHM-1 CAS:154554-41-3

3B Pharmachem (Wuhan) International Co.,Ltd. AdooQ BioScience, LLC EMMX Biotechnology LLC Shanghai EFE Biological Technology Co., Ltd. BOC Sciences ChemeGen(Shanghai) Biotechnology Co.,Ltd. ShangHai ChuanQian Chemcial Technique Centre Energy Chemical MedBioPharmaceutical Technology Inc

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2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158

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