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Methyl 3-hydroxy-4-methylbenzoate

CAS No.
3556-86-3
Chemical Name:
Methyl 3-hydroxy-4-methylbenzoate
Synonyms
3,4-Cresotic acid methyl ester;Methyl 3-hydroxy-4-methylbenzoate;Methyl 4-Methyl-3-hydroxybenzoate;3-HYDROXY-P-TOLUIC ACID METHYL ESTER;Methyl 3-hydroxy-4-methylbenzoate 98%;3-HYDROXY-4-METHYLBENZOIC ACID METHYL ESTER;benzoic acid, 3-hydroxy-4-methyl-, methyl ester
CBNumber:
CB5209910
Molecular Formula:
C9H10O3
Molecular Weight:
166.17
MDL Number:
MFCD00213808
MOL File:
3556-86-3.mol
MSDS File:
SDS
Last updated:2026-09-12 18:53:18

Methyl 3-hydroxy-4-methylbenzoate Properties

Melting point 119.0-120.5 °C
Boiling point 294.6±20.0 °C(Predicted)
Density 1.169±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, Refrigerator, under inert atmosphere
solubility Acetone (Slightly), Chloroform (Slightly)
pka 9.50±0.10(Predicted)
form Solid
color Tan
Stability Hygroscopic
InChI InChI=1S/C9H10O3/c1-6-3-4-7(5-8(6)10)9(11)12-2/h3-5,10H,1-2H3
InChIKey GCSINTLJUNXLLU-UHFFFAOYSA-N
SMILES C(OC)(=O)C1=CC=C(C)C(O)=C1
CAS DataBase Reference 3556-86-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H315-H302-H335
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
HazardClass  IRRITANT

Methyl 3-hydroxy-4-methylbenzoate price More Price(65)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 283450 Methyl 3-hydroxy-4-methylbenzoate Asreported 3556-86-3 2g $399 2026-06-03 Buy
Usbiological 283450 Methyl 3-hydroxy-4-methylbenzoate Asreported 3556-86-3 5g $561 2026-06-03 Buy
Usbiological 283450 Methyl 3-hydroxy-4-methylbenzoate Asreported 3556-86-3 10g $776 2026-06-03 Buy
Usbiological 283450 Methyl 3-hydroxy-4-methylbenzoate Asreported 3556-86-3 25g $1080 2026-06-03 Buy
TRC TRC-M322970-5G Methyl 4-Methyl-3-hydroxybenzoate 3556-86-3 5g $65 2026-06-03 Buy
Product number Packaging Price Buy
283450 2g $399 Buy
283450 5g $561 Buy
283450 10g $776 Buy
283450 25g $1080 Buy
TRC-M322970-5G 5g $65 Buy

Methyl 3-hydroxy-4-methylbenzoate Chemical Properties, Uses, Production

Synthesis

Methyl 3-hydroxy-4-methylbenzoate is synthesized by the following steps:The amino ester 35 (60 g, 0.364 mol) was added to dil. H2SO4 (125 ml  conc. H2SO4 diluted with 1 L water) and warmed on a water bath until all  the compound was dissolved. Cold water (800 ml) was added and the  mixture was cooled to 0 °C. NaNO2 (62.6 g, 0.907 mol) was added to this  mixture with constant stirring. It was then stirred at room temperature for 15 minutes.  Then, urea (65.4 g, 1.09 mol) was added in portions. The mixture was warmed at 50 ºC for  15 minutes (temperature was not allowed to rise above 55 ºC). EtOAc was added to the reaction mixture and washed with brine, dried (anhydrous Na2SO4), filtered and  concentrated under reduced pressure to afford a colourless solid (26.56 g).

Uses

Methyl 4-Methyl-3-hydroxybenzoate is used in the preparation of potent antimalarial agents. Also used in the preparation of aromatic inhibtors of anthranilate synthase.

Methyl 3-hydroxy-4-methylbenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 113)
Supplier Tel Email Country ProdList Advantage
Tianshui YiYao Chemical Co., Ltd. 0938-0938-8493022 15379872136 xiaoshi079@163.com China 2030 58
Shanghai Boyle Chemical Co., Ltd. 021-50182298 021-50180596 sales@boylechem.com China 2202 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Wuhan TCASChem Technology Co., Ltd. 027-86697669 13986148687 sales@tcaschem.com China 3989 55
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9513 58

View Latest Price from Methyl 3-hydroxy-4-methylbenzoate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl 3-Hydroxy-4-methylbenzoate pictures 2024-07-20 Methyl 3-Hydroxy-4-methylbenzoate
3556-86-3
$1.00 1Kg 98% 20T Shaanxi Dideu Medichem Co. Ltd
METHYL 3-HYDROXY-4-METHYLBENZOATE pictures 2020-01-10 METHYL 3-HYDROXY-4-METHYLBENZOATE
3556-86-3
$1.00 1KG 98% 200kgs Career Henan Chemical Co

Methyl 3-hydroxy-4-methylbenzoate Spectrum

benzoic acid, 3-hydroxy-4-methyl-, methyl ester Methyl 4-Methyl-3-hydroxybenzoate 3-HYDROXY-4-METHYLBENZOIC ACID METHYL ESTER 3-HYDROXY-P-TOLUIC ACID METHYL ESTER 3,4-Cresotic acid methyl ester Methyl 3-hydroxy-4-methylbenzoate 98% Methyl 3-hydroxy-4-methylbenzoate 3556-86-3 Esters Phenyls & Phenyl-Het