Methyl 3-hydroxy-4-methylbenzoate
- CAS No.
- 3556-86-3
- Chemical Name:
- Methyl 3-hydroxy-4-methylbenzoate
- Synonyms
- 3,4-Cresotic acid methyl ester;Methyl 3-hydroxy-4-methylbenzoate;Methyl 4-Methyl-3-hydroxybenzoate;3-HYDROXY-P-TOLUIC ACID METHYL ESTER;Methyl 3-hydroxy-4-methylbenzoate 98%;3-HYDROXY-4-METHYLBENZOIC ACID METHYL ESTER;benzoic acid, 3-hydroxy-4-methyl-, methyl ester
- CBNumber:
- CB5209910
- Molecular Formula:
- C9H10O3
- Molecular Weight:
- 166.17
- MDL Number:
- MFCD00213808
- MOL File:
- 3556-86-3.mol
- MSDS File:
- SDS
| Melting point | 119.0-120.5 °C |
|---|---|
| Boiling point | 294.6±20.0 °C(Predicted) |
| Density | 1.169±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, Refrigerator, under inert atmosphere |
| solubility | Acetone (Slightly), Chloroform (Slightly) |
| pka | 9.50±0.10(Predicted) |
| form | Solid |
| color | Tan |
| Stability | Hygroscopic |
| InChI | InChI=1S/C9H10O3/c1-6-3-4-7(5-8(6)10)9(11)12-2/h3-5,10H,1-2H3 |
| InChIKey | GCSINTLJUNXLLU-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=CC=C(C)C(O)=C1 |
| CAS DataBase Reference | 3556-86-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H315-H302-H335 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| HazardClass | IRRITANT |
Methyl 3-hydroxy-4-methylbenzoate price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 283450 | Methyl 3-hydroxy-4-methylbenzoate Asreported | 3556-86-3 | 2g | $399 | 2026-06-03 | Buy |
| Usbiological | 283450 | Methyl 3-hydroxy-4-methylbenzoate Asreported | 3556-86-3 | 5g | $561 | 2026-06-03 | Buy |
| Usbiological | 283450 | Methyl 3-hydroxy-4-methylbenzoate Asreported | 3556-86-3 | 10g | $776 | 2026-06-03 | Buy |
| Usbiological | 283450 | Methyl 3-hydroxy-4-methylbenzoate Asreported | 3556-86-3 | 25g | $1080 | 2026-06-03 | Buy |
| TRC | TRC-M322970-5G | Methyl 4-Methyl-3-hydroxybenzoate | 3556-86-3 | 5g | $65 | 2026-06-03 | Buy |
Methyl 3-hydroxy-4-methylbenzoate Chemical Properties, Uses, Production
Synthesis
Methyl 3-hydroxy-4-methylbenzoate is synthesized by the following steps:The amino ester 35 (60 g, 0.364 mol) was added to dil. H2SO4 (125 ml conc. H2SO4 diluted with 1 L water) and warmed on a water bath until all the compound was dissolved. Cold water (800 ml) was added and the mixture was cooled to 0 °C. NaNO2 (62.6 g, 0.907 mol) was added to this mixture with constant stirring. It was then stirred at room temperature for 15 minutes. Then, urea (65.4 g, 1.09 mol) was added in portions. The mixture was warmed at 50 ºC for 15 minutes (temperature was not allowed to rise above 55 ºC). EtOAc was added to the reaction mixture and washed with brine, dried (anhydrous Na2SO4), filtered and concentrated under reduced pressure to afford a colourless solid (26.56 g).
Uses
Methyl 4-Methyl-3-hydroxybenzoate is used in the preparation of potent antimalarial agents. Also used in the preparation of aromatic inhibtors of anthranilate synthase.
Methyl 3-hydroxy-4-methylbenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianshui YiYao Chemical Co., Ltd. | 0938-0938-8493022 15379872136 | xiaoshi079@163.com | China | 2030 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 3989 | 55 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
View Latest Price from Methyl 3-hydroxy-4-methylbenzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2024-07-20 | Methyl 3-Hydroxy-4-methylbenzoate
3556-86-3
|
$1.00 | 1Kg | 98% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
![]() |
2020-01-10 | METHYL 3-HYDROXY-4-METHYLBENZOATE
3556-86-3
|
$1.00 | 1KG | 98% | 200kgs | Career Henan Chemical Co |
-

- Methyl 3-Hydroxy-4-methylbenzoate
3556-86-3
- $1.00
- 98%
- Shaanxi Dideu Medichem Co. Ltd
-

- METHYL 3-HYDROXY-4-METHYLBENZOATE
3556-86-3
- $1.00
- 98%
- Career Henan Chemical Co
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