1,10-Phenanthrolinium chloride monohydrate
- CAS No.
- 18851-33-7
- Chemical Name:
- 1,10-Phenanthrolinium chloride monohydrate
- Synonyms
- 1,10-PHENANTHROLINE HYDROCHLORIDE;1,10-PhenanthrolineHydrochlorideGr;1,10-PHENANTHROLINE CHLORIDE MONOHYDRATE;1,10-Phenanthroline hydrochloride hydrate;10-Phenanthrolinehydrochloridemonohydrate;O-PHENANTHROLINE HYDROCHLORIDE MONOHYDRATE;1,10-Phenanthroline hydrochloride, GR 99%+;1,10-Phenanthrolinium chloride monohydrate;o-Phenanthroline monohydrate hydrochloride;1,10-PHENANTHROLINE HYDROCHLORIDE MONOHYDRATE
- CBNumber:
- CB5230613
- Molecular Formula:
- C12H11ClN2O
- Molecular Weight:
- 234.68
- MDL Number:
- MFCD00150061
- MOL File:
- 18851-33-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 224-225 °C(lit.) |
|---|---|
| bulk density | 370kg/m3 |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | H2O: 0.1 g/mL, clear |
| form | Solid |
| color | Colorless crystals |
| Water Solubility | Soluble in water. |
| BRN | 4007967 |
| Stability | Stable for 2 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months. |
| InChI | 1S/C12H8N2.ClH.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;;/h1-8H;1H;1H2 |
| InChIKey | NDLHUHRGAIHALB-UHFFFAOYSA-N |
| SMILES | O.Cl.c1cnc2c(c1)ccc3cccnc23 |
| UNSPSC Code | 12352107 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS06,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H410 | |||||||||
| Precautionary statements | P264-P270-P273-P301+P310-P391-P405 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T,N | |||||||||
| Risk Statements | 25-50/53 | |||||||||
| Safety Statements | 45-60-61 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 2933 99 80 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Aquatic Acute 1 Aquatic Chronic 1 |
|||||||||
| Toxicity | LD50 orally in Rabbit: 132 mg/kg | |||||||||
| NFPA 704 |
|
1,10-Phenanthrolinium chloride monohydrate price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 77510 | 1,10-Phenanthroline hydrochloride monohydrate ≥99.5% (titration) | 18851-33-7 | 5g | $55.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | 77510 | 1,10-Phenanthroline hydrochloride monohydrate ≥99.5% (titration) | 18851-33-7 | 25g | $132 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1.07223 | 1,10-Phenanthroline chloride monohydrate GR for analysis and redox indicator [reagent for iron(II)] Reag. Ph Eur | 18851-33-7 | 10g | $139 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1.07223 | 1,10-Phenanthroline chloride monohydrate GR for analysis and redox indicator [reagent for iron(II)] Reag. Ph Eur | 18851-33-7 | 100g | $887 | 2026-04-30 | Buy |
| TCI Chemical | P0081 | 1,10-Phenanthroline Hydrochloride Monohydrate >99.0%(T) | 18851-33-7 | 25g | $108 | 2026-04-30 | Buy |
1,10-Phenanthrolinium chloride monohydrate Chemical Properties,Uses,Production
Description
1,10-Phenanthroline (18851-33-7) is a high affinity chelator of divalent metal ions and may be used to inhibit zinc metalloenzymes.1 It is a potent inhibitor of JAMM-type isopeptidases (DUBs) acting via chelation of an active site Zn2+. It may be used when preparing cell lysates for enrichment of ubiquitinated proteins which are especially sensitive to DUBs in the JAMM family.2,3
Chemical Properties
White fine crystalline powder
Uses
1,10-Phenanthroline monohydrochloride monohydrate is used as an analytical reagent for colorimetric determination of iron.
References
[1] J C SWANN W A G J J Reynolds. Zinc metalloenzyme properties of active and latent collagenase from rabbit bone.[J]. Biochemical Journal, 1981, 195 1: 41-49. DOI:10.1042/bj1950041
[2] ERIC M COOPER. K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1.[J]. EMBO Journal, 2009, 28 6: 621-631. DOI:10.1038/emboj.2009.27
[3] YING LU. Substrate degradation by the proteasome: A single-molecule kinetic analysis[J]. Science, 2015, 348 6231. DOI:10.1126/science.1250834
1,10-Phenanthrolinium chloride monohydrate Preparation Products And Raw materials
Raw materials
Preparation Products
1,10-Phenanthrolinium chloride monohydrate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
View Lastest Price from 1,10-Phenanthrolinium chloride monohydrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-14 | o-Phenanthroline monohydrochloride monohydrate
18851-33-7
|
$12.20-75.30 | 25g | 0.98 | 25kg | Shanghai UCHEM Inc. | |
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2026-08-20 | 1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE
18851-33-7
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
![]() |
2025-06-27 | 1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE
18851-33-7
|
1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd |
-

- o-Phenanthroline monohydrochloride monohydrate
18851-33-7
- $12.20-75.30
- 0.98
- Shanghai UCHEM Inc.
-

- 1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE
18851-33-7
- $1.10
- 99.00%
- Dideu Industries Group Limited
-

- 1,10-PHENANTHROLINIUM CHLORIDE MONOHYDRATE
18851-33-7
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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