UNC 0638
- CAS No.
- 1255517-77-1
- Chemical Name:
- UNC 0638
- Synonyms
- 4-QuinazolinaMine, 2-cyclohexyl-6-Methoxy-N-[1-(1-Methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-, hydrate;2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)piperidin-4-yl]-7-[3-(pyrrolidin-1-yl)-propoxy]-4-amino-quinazoline hydrate;2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-Quinazolinamine hydrate (1:1);4-Quinazolinamine, 2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-, hydrate (1:1)
- CBNumber:
- CB52596524
- Molecular Formula:
- C30H49N5O3
- Molecular Weight:
- 527.75
- MDL Number:
- MFCD22208587
- MOL File:
- 1255517-77-1.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300-H413 |
| Precautionary statements | P264-P270-P273-P301+P310-P405-P501 |
| WGK Germany | WGK 3 |
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
| Hazard Classifications | Acute Tox. 2 Oral Aquatic Chronic 4 |
UNC 0638 price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | U4885 | UNC0638 hydrate ≥98% (HPLC) | 1255517-77-1 | 5 mg | $236 | 2026-04-30 | Buy |
| Sigma-Aldrich | U4885 | UNC0638 hydrate ≥98% (HPLC) | 1255517-77-1 | 25 mg | $912 | 2026-04-30 | Buy |
| TRC | U712703 | UNC0638Hydrate | 1255517-77-1 | 10mg | $235 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001554 | UNC-0638 99.00% | 1255517-77-1 | 2MG | $427 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001554 | UNC-0638 99.00% | 1255517-77-1 | 1G | $4140 | 2021-12-16 | Buy |
UNC 0638 Chemical Properties, Uses, Production
Uses
UNC 0638 is a useful intermediate.
Definition
ChEBI: 2-cyclohexyl-6-methoxy-N-(1-propan-2-yl-4-piperidinyl)-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine is a member of quinazolines.
Biological Activity
UNC0638 hydrate is a histone methyltransferase (HMT) inhibitor. UNC0638 shows selectivity for G9a (EHMT2) and GLP (EHMT1) methyltransferases, which catalyze the methylation of lysine 9 of histone 3 (H3K9) as well as other non-histone substrates. For full characterization details, please visit the UNC0638 probe summary on the Structural Genomics Consortium (SGC) website.
To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
UNC 0638 Preparation Products And Raw materials
Raw materials
Preparation Products
UNC 0638 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| AdooQ Bioscience CHINA | 025-58849295 | info@adooq.cn | China | 2981 | 60 |
| Shanghai Changyan Chem & Tech Co., Ltd. | 021-20242659 18930833303 | sales@changyanchem.cn | China | 4998 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Huai Hua Binfengchem Co., Ltd | 0745-2866851 17711757908 | 3907837691@qq.com | China | 4745 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
