MPEG16-Propyne
- CAS No.
- 2169967-47-7
- Chemical Name:
- MPEG16-Propyne
- Synonyms
- MPEG16-Propyne;m-PEG16-propargyl;2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne;mPEG16-Propyne/2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxatripentacont-52-yne;Propargyl PEG17 methane,PROTAC Linkers,inhibit,PropargylPEG17methane,Inhibitor,Propargyl-PEG-17-methane
- CBNumber:
- CB52656925
- Molecular Formula:
- C36H70O17
- Molecular Weight:
- 774.93
- MDL Number:
- MFCD27977517
- MOL File:
- 2169967-47-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
MPEG16-Propyne price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemPep | 283906-250MG | mPEG16-Propyne | 250mg | $387 | 2026-06-04 | Buy | |
| ChemPep | 283906-1G | mPEG16-Propyne | 1g | $795 | 2026-06-04 | Buy | |
| ChemScene | CS-0115236 | Propargyl-PEG17-methane ≥98% | 2169967-47-7 | 25mg | $164 | 2026-06-04 | Buy |
| ChemScene | CS-0115236 | Propargyl-PEG17-methane ≥98% | 2169967-47-7 | 50mg | $261 | 2026-06-04 | Buy |
| ChemScene | CS-0115236 | Propargyl-PEG17-methane ≥98% | 2169967-47-7 | 100mg | $417 | 2026-06-04 | Buy |
MPEG16-Propyne Chemical Properties, Uses, Production
Uses
Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG17-methane is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Biological Activity
Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
MPEG16-Propyne Preparation Products And Raw materials
Raw materials
Preparation Products
MPEG16-Propyne Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChemPep, Inc. | +1 (888) 615-9178 / (561) 791-8787 | service@chempep.com | United States | 2138 | 57 |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28760 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Affinity（Wuhan）Ltd. | 15841022315 | sales@affinitytech.cn | China | 2982 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 9992 | 58 |
| Shandong fen Boyu Biotechnology Co.,LTD | 13356310019 13356310019; | boyu2024@163.com | China | 3947 | 58 |
| Hubei wei shi reagent group ltd., company | 17771898297 13125137661 | 2853877621@qq.com | China | 7992 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Shanghai Yanfen Biochemical Technology Co.,LTD | 13611955358 15002190549 | yanfen2023@126.com | China | 2573 | 58 |
View Latest Price from MPEG16-Propyne manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Propargyl-PEG17-methane
2169967-47-7
|
$33.00-75.00 | 99.69% | 10g | TargetMol Chemicals Inc. |
-
- Propargyl-PEG17-methane
2169967-47-7
- $33.00-75.00
- 99.69%
- TargetMol Chemicals Inc.
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