3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
- CAS No.
- 10128-71-9
- Chemical Name:
- 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
- Synonyms
- 3-Hydroxyisonicotinicaci;3-HYDROXYISONICOTINIC ACID;3-Hydroxy-4-carboxypyridine;3-HydroxyisonicotinicAcid>3-hydroxypyridin-4-carboxylic acid;3-Hydroxy-4-pyridinecaboxylic acid;3-HYDROXY-4-PYRIDINECARBOXYLIC ACID;3-HYDROXY PYRIDINE-4-CARBOXYLIC ACID;4-Pyridinecarboxylic acid, 3-hydroxy-;3-Hydroxy-4-pyridinecarboxylic acid ,97%
- CBNumber:
- CB5280168
- Molecular Formula:
- C6H5NO3
- Molecular Weight:
- 139.11
- MDL Number:
- MFCD00234165
- MOL File:
- 10128-71-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Hydroxyisonicotinic Acid >98.0%(HPLC)(T) | H1377 | 1g | $59 |
| 3-Hydroxyisonicotinic Acid >98.0%(HPLC)(T) | H1377 | 5g | $236 |
| 3-Hydroxyisonicotinic Acid | H943565 | 1g | $130 |
| 3-HYDROXYISONICOTINIC ACID 95.00% | CHM0023627 | 500MG | $791.52 |
| 3-HYDROXYISONICOTINIC ACID 95.00% | CHM0023627 | 1G | $866.13 |
| More product size | |||
| Melting point | 317-319(dec.) |
|---|---|
| Boiling point | 519.3±35.0 °C(Predicted) |
| Density | 1.485±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 0.51±0.10(Predicted) |
| form | Solid |
| color | Light yellow to Brown |
| Water Solubility | Soluble in methanol. Slightly soluble in water. |
| CAS DataBase Reference | 10128-71-9(CAS DataBase Reference) |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
3-HYDROXY-4-PYRIDINECARBOXYLIC ACID price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | H1377 | 3-Hydroxyisonicotinic Acid >98.0%(HPLC)(T) | 10128-71-9 | 1g | $59 | 2025-07-31 | Buy |
| TCI Chemical | H1377 | 3-Hydroxyisonicotinic Acid >98.0%(HPLC)(T) | 10128-71-9 | 5g | $236 | 2025-07-31 | Buy |
| TRC | H943565 | 3-Hydroxyisonicotinic Acid | 10128-71-9 | 1g | $130 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0023627 | 3-HYDROXYISONICOTINIC ACID 95.00% | 10128-71-9 | 500MG | $791.52 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0023627 | 3-HYDROXYISONICOTINIC ACID 95.00% | 10128-71-9 | 1G | $866.13 | 2021-12-16 | Buy |
3-HYDROXY-4-PYRIDINECARBOXYLIC ACID Chemical Properties,Uses,Production
Chemical Properties
Light yellow solid
Uses
3-Hydroxyisonicotinic Acid is used in the preparation of chelating agents for iron and aluminum.
Synthesis
7579-20-6
10128-71-9
Step B: Synthesis of 3-hydroxyisonicotinic acid: 3-aminoisonicotinic acid (108.86 g, 788.13 mmol) was dissolved in water (1740 mL), followed by slow addition of sulfuric acid (84.020 mL, 1576.3 mmol). The resulting yellow slurry was cooled to below 10°C and a solution of sodium nitrite (60.359 g, 874.83 mmol) in water (510 mL) was added dropwise while maintaining the temperature below 10°C. Subsequently, the reaction mixture was heated to 80°C, at which point a large amount of precipitate generation was observed. After the suspension was cooled to 65°C, glacial acetic acid (88 mL, continuous decantation) and concentrated ammonium hydroxide (190 mL) were added sequentially to adjust the final pH to about 4.5. The precipitate was collected by vacuum filtration and washed with cold water. The solid was dried in air for 16 h to give the final free flowing granular 3-hydroxyisonicotinic acid (99.37 g, 91% yield).
References
[1] Patent: US2007/49603, 2007, A1. Location in patent: Page/Page column 78; 30
[2] Patent: WO2008/24725, 2008, A1. Location in patent: Page/Page column 67
[3] Journal of Medicinal Chemistry, 2017, vol. 60, # 16, p. 6942 - 6990
3-HYDROXY-4-PYRIDINECARBOXYLIC ACID Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10405 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8830 | 58 |
View Lastest Price from 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
10128-71-9
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2021-10-26 | 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
10128-71-9
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2021-07-13 | 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
10128-71-9
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
10128-71-9
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
10128-71-9
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
10128-71-9
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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