3-Hydroxy-4-pyridinecarboxylic acid
- CAS No.
- 10128-71-9
- Chemical Name:
- 3-Hydroxy-4-pyridinecarboxylic acid
- Synonyms
- 3-HYDROXYISONICOTINIC ACID;3-Hydroxyisonicotinicaci;3-Hydroxy-4-carboxypyridine;3-HydroxyisonicotinicAcid>3-hydroxypyridin-4-carboxylic acid;3-Hydroxy-4-pyridinecaboxylic acid;3-Hydroxy-4-pyridinecarboxylic acid;3-HYDROXY PYRIDINE-4-CARBOXYLIC ACID;4-Pyridinecarboxylic acid, 3-hydroxy-;3-Hydroxy-4-pyridinecarboxylic acid ,97%
- CBNumber:
- CB5280168
- Molecular Formula:
- C6H5NO3
- Molecular Weight:
- 139.11
- MDL Number:
- MFCD00234165
- MOL File:
- 10128-71-9.mol
- MSDS File:
- SDS
| Melting point | 317-319(dec.) |
|---|---|
| Boiling point | 519.3±35.0 °C(Predicted) |
| Density | 1.485±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 0.51±0.10(Predicted) |
| form | Solid |
| color | Light yellow to Brown |
| Water Solubility | Soluble in methanol. Slightly soluble in water. |
| InChI | 1S/C6H5NO3/c8-5-3-7-2-1-4(5)6(9)10/h1-3,8H,(H,9,10) |
| InChIKey | JEHGATQUCUYHJL-UHFFFAOYSA-N |
| SMILES | OC(=O)c1ccncc1O |
| CAS DataBase Reference | 10128-71-9(CAS DataBase Reference) |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
3-Hydroxy-4-pyridinecarboxylic acid price More Price(66)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | H1377 | 3-Hydroxyisonicotinic Acid >98.0%(HPLC)(T) | 10128-71-9 | 1g | $85 | 2026-04-30 | Buy |
| TCI Chemical | H1377 | 3-Hydroxyisonicotinic Acid >98.0%(HPLC)(T) | 10128-71-9 | 5g | $341 | 2026-04-30 | Buy |
| AstaTech | CL0149 | 3-HYDROXY-4-PYRIDINECARBOXYLICACID 97% | 10128-71-9 | 5G | $24 | 2026-04-30 | Buy |
| AstaTech | CL0149 | 3-HYDROXY-4-PYRIDINECARBOXYLICACID 97% | 10128-71-9 | 25G | $102 | 2026-04-30 | Buy |
| Apolloscientific | OR12100 | 3-Hydroxyisonicotinic acid ≥95% | 10128-71-9 | 1g | $21 | 2026-06-04 | Buy |
3-Hydroxy-4-pyridinecarboxylic acid Chemical Properties,Uses,Production
Chemical Properties
Light yellow solid
Uses
3-Hydroxyisonicotinic Acid is used in the preparation of chelating agents for iron and aluminum.
Synthesis
7579-20-6
10128-71-9
Step B: Synthesis of 3-hydroxyisonicotinic acid: 3-aminoisonicotinic acid (108.86 g, 788.13 mmol) was dissolved in water (1740 mL), followed by slow addition of sulfuric acid (84.020 mL, 1576.3 mmol). The resulting yellow slurry was cooled to below 10°C and a solution of sodium nitrite (60.359 g, 874.83 mmol) in water (510 mL) was added dropwise while maintaining the temperature below 10°C. Subsequently, the reaction mixture was heated to 80°C, at which point a large amount of precipitate generation was observed. After the suspension was cooled to 65°C, glacial acetic acid (88 mL, continuous decantation) and concentrated ammonium hydroxide (190 mL) were added sequentially to adjust the final pH to about 4.5. The precipitate was collected by vacuum filtration and washed with cold water. The solid was dried in air for 16 h to give the final free flowing granular 3-hydroxyisonicotinic acid (99.37 g, 91% yield).
References
[1] Patent: US2007/49603, 2007, A1. Location in patent: Page/Page column 78; 30
[2] Patent: WO2008/24725, 2008, A1. Location in patent: Page/Page column 67
[3] Journal of Medicinal Chemistry, 2017, vol. 60, # 16, p. 6942 - 6990
3-Hydroxy-4-pyridinecarboxylic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
View Lastest Price from 3-Hydroxy-4-pyridinecarboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
10128-71-9
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2025-04-04 | 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
10128-71-9
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2021-07-13 | 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
10128-71-9
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
10128-71-9
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
10128-71-9
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 3-HYDROXY-4-PYRIDINECARBOXYLIC ACID
10128-71-9
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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