ChemicalBook >> CAS DataBase List >>(T-4)-[N-[(Carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO][4-[(5,6-dichloro-2-methyl-4-nitro-1H-benzimidazol-1-yl)methyl]phenyl]boron

(T-4)-[N-[(Carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO][4-[(5,6-dichloro-2-methyl-4-nitro-1H-benzimidazol-1-yl)methyl]phenyl]boron

CAS No.
1862212-48-3
Chemical Name:
(T-4)-[N-[(Carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO][4-[(5,6-dichloro-2-methyl-4-nitro-1H-benzimidazol-1-yl)methyl]phenyl]boron
Synonyms
TH 1217;3,TH1217;2-[4-[(5,6-Dichloro-2-methyl-4-nitrobenzimidazol-1-yl)methyl]phenyl]-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione;2-[4-[[5,6-Dichloro-2-methyl-4-nitro-1H-benzo[d]-imidazol-1-yl]methyl]phenyl]-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione;(T-4)-[N-[(Carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO][4-[(5,6-dichloro-2-methyl-4-nitro-1H-benzimidazol-1-yl)methyl]phenyl]boron;Boron, [N-[(carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO][4-[(5,6-dichloro-2-methyl-4-nitro-1H-benzimidazol-1-yl)methyl]phenyl]-, (T-4)-
CBNumber:
CB53155120
Molecular Formula:
C20H17BCl2N4O6
Molecular Weight:
491.09
MDL Number:
MFCD34470038
MOL File:
1862212-48-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:07
Product description Number Pack Size Price
TH1217 ≥98% 43599 5mg $105
TH1217 ≥98% 43599 10mg $168
TH1217 ≥98% 43599 25mg $314
TH1217 ≥98% 43599 50mg $523
TH1217 97.04% CS-0116236 5mg $108

(T-4)-[N-[(Carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO][4-[(5,6-dichloro-2-methyl-4-nitro-1H-benzimidazol-1-yl)methyl]phenyl]boron Properties

storage temp. Store at -20°C
solubility Soluble in DMSO
form Solid
color White to off-white

(T-4)-[N-[(Carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO][4-[(5,6-dichloro-2-methyl-4-nitro-1H-benzimidazol-1-yl)methyl]phenyl]boron price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 43599 TH1217 ≥98% 1862212-48-3 5mg $105 2026-04-30 Buy
Cayman Chemical 43599 TH1217 ≥98% 1862212-48-3 10mg $168 2026-04-30 Buy
Cayman Chemical 43599 TH1217 ≥98% 1862212-48-3 25mg $314 2026-04-30 Buy
Cayman Chemical 43599 TH1217 ≥98% 1862212-48-3 50mg $523 2026-04-30 Buy
ChemScene CS-0116236 TH1217 97.04% 1862212-48-3 5mg $108 2026-06-04 Buy
Product number Packaging Price Buy
43599 5mg $105 Buy
43599 10mg $168 Buy
43599 25mg $314 Buy
43599 50mg $523 Buy
CS-0116236 5mg $108 Buy

(T-4)-[N-[(Carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO][4-[(5,6-dichloro-2-methyl-4-nitro-1H-benzimidazol-1-yl)methyl]phenyl]boron Chemical Properties,Uses,Production

Uses

TH1217 (ZINC1775962367) is a potent and selective dCTPase pyrophosphatase 1 (dCTPase) inhibitor, with an IC50 of 47 nM. TH1217 enhances the cytotoxic effect of cytidine analogues in leukemia cells. TH1217 also could modulate SARS-Cov-2 interactors, so it shows activity of against COVID-19[1][2].

storage

Store at -20°C

References

[1] Llona-Minguez S, et, al. Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1. Med Chem. 2016 Feb 11; 59(3): 1140-1148. DOI:10.1021/acs.jmedchem.5b01741
[2] Gordon DE, et, al. A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing. bioRxiv. 2020 Mar 22; 2020.03.22.002386. DOI:10.1101/2020.03.22.002386

(T-4)-[N-[(Carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO][4-[(5,6-dichloro-2-methyl-4-nitro-1H-benzimidazol-1-yl)methyl]phenyl]boron Preparation Products And Raw materials

Raw materials

Preparation Products

(T-4)-[N-[(Carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO][4-[(5,6-dichloro-2-methyl-4-nitro-1H-benzimidazol-1-yl)methyl]phenyl]boron Suppliers

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(T-4)-[N-[(Carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO][4-[(5,6-dichloro-2-methyl-4-nitro-1H-benzimidazol-1-yl)methyl]phenyl]boron Spectrum

1862212-48-3((T-4)-[N-[(Carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO][4-[(5,6-dichloro-2-methyl-4-nitro-1H-benzimidazol-1-yl)methyl]phenyl]boron)Related Search:

2-[4-[[5,6-Dichloro-2-methyl-4-nitro-1H-benzo[d]-imidazol-1-yl]methyl]phenyl]-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione TH 1217 (T-4)-[N-[(Carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO][4-[(5,6-dichloro-2-methyl-4-nitro-1H-benzimidazol-1-yl)methyl]phenyl]boron 3,TH1217 Boron, [N-[(carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO][4-[(5,6-dichloro-2-methyl-4-nitro-1H-benzimidazol-1-yl)methyl]phenyl]-, (T-4)- 2-[4-[(5,6-Dichloro-2-methyl-4-nitrobenzimidazol-1-yl)methyl]phenyl]-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione 1862212-48-3