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ChemicalBook >> CAS DataBase List >>4,4,4-Trifluoro-1-phenyl-1,3-butanedione

4,4,4-Trifluoro-1-phenyl-1,3-butanedione

4,4,4-Trifluoro-1-phenyl-1,3-butanedione Structure
4,4,4-Trifluoro-1-phenyl-1,3-butanedione structure
CAS No.
326-06-7
Chemical Name:
4,4,4-Trifluoro-1-phenyl-1,3-butanedione
Synonyms
4,4,4-TRIFLUORO-1-PHENYLBUTANE-1,3-DIONE;BENZOYLTRIFLUOROACETONE;3-BENZOYL-1,1,1-TRIFLUOROACETONE;BENZOYL-1,1,1-TRIFLUOROACETONE;NSC 42628;NSC 405720;AKOS MSC-0330;Celecoxib Impurity 35;LABOTEST-BB LT00005189;4-Phenyl-1,1,1-trifluorobuta
CBNumber:
CB5331972
Molecular Formula:
C10H7F3O2
Molecular Weight:
216.16
MDL Number:
MFCD00000425
MOL File:
326-06-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:59:12
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4,4,4-Trifluoro-1-phenyl-1,3-butanedione Properties

Melting point 38-40 °C(lit.)
Boiling point 224 °C(lit.)
Density 1,113 g/cm3
Flash point 210 °F
storage temp. Sealed in dry,Room Temperature
solubility 95% ethanol: soluble25mg/mL, clear, colorless to yellow
form Crystalline Low Melting Solid
pka pK1: 6.35 (25°C)
color White to yellow
Water Solubility Sparingly Soluble in water (0.24 g/L) (25°C).
BRN 1875083
InChI InChI=1S/C10H7F3O2/c11-10(12,13)9(15)6-8(14)7-4-2-1-3-5-7/h1-5H,6H2
InChIKey VVXLFFIFNVKFBD-UHFFFAOYSA-N
SMILES C(C1=CC=CC=C1)(=O)CC(=O)C(F)(F)F
CAS DataBase Reference 326-06-7(CAS DataBase Reference)
EPA Substance Registry System 1,3-Butanedione, 4,4,4-trifluoro-1-phenyl- (326-06-7)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25
WGK Germany  3
TSCA  TSCA listed
HazardClass  IRRITANT
HS Code  29147000
Storage Class 11 - Combustible Solids
NFPA 704
1
2 0

4,4,4-Trifluoro-1-phenyl-1,3-butanedione price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 217042 4,4,4-Trifluoro-1-phenyl-1,3-butanedione 99% 326-06-7 25g $101 2026-04-30 Buy
TCI Chemical T0437 4,4,4-Trifluoro-1-phenyl-1,3-butanedione >98.0%(GC) 326-06-7 25g $123 2026-04-30 Buy
Strem Chemicals 09-1210 Benzoyl-1,1,1-trifluoroacetone, 98% 326-06-7 10g $45 2024-03-01 Buy
Strem Chemicals 09-1210 Benzoyl-1,1,1-trifluoroacetone, 98% 326-06-7 50g $138 2024-03-01 Buy
Apolloscientific PC1210 3-Benzoyl-1,1,1-trifluoroacetone 97% 326-06-7 5g $21 2026-06-04 Buy
Product number Packaging Price Buy
217042 25g $101 Buy
T0437 25g $123 Buy
09-1210 10g $45 Buy
09-1210 50g $138 Buy
PC1210 5g $21 Buy

4,4,4-Trifluoro-1-phenyl-1,3-butanedione Chemical Properties,Uses,Production

Chemical Properties

WHITE TO YELLOW CRYSTALLINE LOW MELTING SOLID

Uses

4,4,4-Trifluoro-1-phenyl-1,3-butanedione was used in the synthesis of series of NNO ketoimines bearing trifluoromethyl substituents via Schiff base condensation reaction. It was also used in mixed-ligand chelate extraction of trivalent lanthanides and as a ligand in the preparation of ternary lanthanide (Ln) complexes.

Synthesis

To a three-necked flask fitted with magnetic stirring, a dropping funnel and an inert gas device, 2 mL of anhydrous methanol was added with stirring and 0.230 g (10 ) of clean sodium metal crumbs were added. mmol) of clean sodium metal crumbs, and after all the sodium was dissolved, a water bath was installed to evaporate the unreacted methanol in the reaction system. After the sodium methanol was completely dried, 5 was added mL of anhydrous ether, quickly stirred well, and then cooled in an ice bath. 1.2 mL (10 mmol) of ethyl trifluoroacetate was diluted with 5 mL of anhydrous ether was diluted and added to the reaction flask. The ice bath was removed and 1.1 mL (10 mmol) acetophenone was diluted with 5 mL of anhydrous ether was diluted and added dropwise to the reaction system using a dropping funnel. The reaction was stirred at reflux for five hours and at the end of the reaction 10 was added mL of water was added to dissolve the resulting solid and the mixture was extracted with ether to remove unreacted ketones and esters. The aqueous phase was acidified with 0.5 mL (10 ) glacial acetic acid was acidified and then extracted with ether in portions, the organic phases were combined, dried with anhydrous magnesium sulfate and filtered. After the filtrate was evaporated from the ether, a light-yellow crystalline low-melting solid powder 1.691 was precipitated. g. The light yellow solid powder was recrystallized with ethanol-water to obtain light yellow pure benzoyltrifluoroacetone.

4,4,4-Trifluoro-1-phenyl-1,3-butanedione synthesis

383-63-1
98-86-2
326-06-7
Synthesis of 4,4,4-Trifluoro-1-phenyl-1,3-butanedione from Ethyl trifluoroacetate and Acetophenone

4,4,4-Trifluoro-1-phenyl-1,3-butanedione Preparation Products And Raw materials

Raw materials

Sodium Acetophenone Ethyl trifluoroacetate

Preparation Products

2-Oxo-6-phenyl-4-(trifluoromethyl)-1,2-dihydro-3-pyridinecarbonitrile methyl {[3-cyano-4-(4-methoxyphenyl)-6-phenyl-2-pyridinyl]sulfanyl}acetate

4,4,4-Trifluoro-1-phenyl-1,3-butanedione Suppliers

Global( 297)Suppliers
Supplier Tel Email Country ProdList Advantage
Fluoropharm Co., Ltd. 0571-85586753 13336034509 sales@fluoropharm.com China 1288 58
Tianjin Security-Chemical Technology Co., Ltd. 22-23128588 +86-13312123508 sale@security-chemical.com China 20 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Supplier Advantage
Fluoropharm Co., Ltd. 58
Tianjin Security-Chemical Technology Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66

View Lastest Price from 4,4,4-Trifluoro-1-phenyl-1,3-butanedione manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4,4,4-Trifluoro-1-phenyl-1,3-butanedione pictures 2025-06-11 4,4,4-Trifluoro-1-phenyl-1,3-butanedione
326-06-7
 $220.00-260.00 1kg 98% 5mt Sach biotech Co.,Ltd
4,4,4-Trifluoro-1-phenyl-1,3-butanedione pictures 2025-04-04 4,4,4-Trifluoro-1-phenyl-1,3-butanedione
326-06-7
 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
BENZOYL-1,1,1-TRIFLUOROACETONE pictures 2019-07-06 BENZOYL-1,1,1-TRIFLUOROACETONE
326-06-7
 $8.00 1kg 99% 10MT Career Henan Chemical Co

4,4,4-Trifluoro-1-phenyl-1,3-butanedione Spectrum

4,4,4-Trifluoro-1-phenyl-1,3-butanedione(326-06-7)MS4,4,4-Trifluoro-1-phenyl-1,3-butanedione(326-06-7)1HNMR4,4,4-Trifluoro-1-phenyl-1,3-butanedione(326-06-7)13CNMR4,4,4-Trifluoro-1-phenyl-1,3-butanedione(326-06-7)IR14,4,4-Trifluoro-1-phenyl-1,3-butanedione(326-06-7)IR24,4,4-Trifluoro-1-phenyl-1,3-butanedione(326-06-7)IR34,4,4-Trifluoro-1-phenyl-1,3-butanedione(326-06-7)Raman

326-06-7(4,4,4-Trifluoro-1-phenyl-1,3-butanedione)Related Search:

4,4,4-Trifluoro-1-phenyl-1,3-butanedione 4,4,4-Trifluoro-1-(p-tolyl)-1,3-butanedione Fluoroacetone Acetone 1,1,1-Trifluoroacetone
Benzoylacetone 4,4,4-Trifluoro-1-(4-methoxyphenyl)-1,3-butanedione 4,4,4-Trifluoro-1-(2-naphthyl)-1,3-butanedione 1-(4-Chlorophenyl)-4,4,4-trifluoro-1,3-butanedione 4,4,4-Trifluoro-1-(4-fluorophenyl)butane-1,3-dione
3-[3,4-(METHYLENEDIOXY)BENZOYL]-1,1,1-TRIFLUOROACETONE,3-[3,4-(METHYLENEDIXOY)BENZOYL]-1,1,1-TRIFLUOROACETONE 1-(4-DIFLUOROMETHOXY-3-METHOXY-PHENYL)-4,4,4-TRIFLUORO-BUTANE-1,3-DIONE 1-(2-CHLOROPHENYL)-4,4,4-TRIFLUOROBUTANE-1,3-DIONE 1-(4-DIFLUOROMETHOXY-PHENYL)-4,4,4-TRIFLUORO-BUTANE-1,3-DIONE 4,4,4-trifluoro-1-(4-nitrophenyl)butane-1,3-dione
1-(3,4-DIMETHOXYPHENYL)-4,4,4-TRIFLUOROBUTANE-1,3-DIONE 4,4,4-TRIFLUORO-1-(3-METHOXY-PHENYL)-BUTANE-1,3-DIONE 1-(4-BIPHENYLYL)-4,4,4-TRIFLUORO-1,3-BUTANEDIONE

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TRIFLUORO-1-PHENYL-1,3-BUTANEDIONE 1,1,1-Trifluoro-4-phenyl-2,4-butanedione 1-Benzoyl-3,3,3-trifluoro-2-propanone 1-Benzoyl-3,3,3-trifluoroacetone 4,4,4-Trifluoro-1-phenylbutane-1,3-dione ,98% ω-(Trifluoroacetyl)acetophenone 4,4,4-Trifluoro-1-phenyl-1,3-butanedione,99% 4-Phenyl-1,1,1-trifluorobuta 4,4,4-Trifluoro-1-phenyl-1,3-butanedione 99% 3-BENZOYL-1,1,1-TRIFLUOROACETONE 1,1,1-TRIFLUORO-4-PHENYLBUTANE-2,4-DIONE BENZOYL-1 1 1-TRIFLUOROACETONE 98% Benzoyltrifluoroacetone, 98+% BENZOYL-1,1,1-TRIFLUOROACETONE IN TOLUENE Benzoyl-1,1,1-trifluoroacetone,98% 3-Benzoyl 1,1,1-trifluoroacetate 3-Benzoyl-1,1,1-trifluoroacetone 98% 3-Benzoyl-1,1,1-trifluoroacetone98% 1-Phenyl-4,4,4-trifluorobutane-1,3-dione NSC 405720 NSC 42628 1-Phenyl-4,4,4-trifluoro-1,3-butanedione 4,4,4-trifluoro-1-phenyl-3-butanedione 4-Phenyl-1,1,1-trifluorobutane-2,4-dione Benzoyl(trifluoroacetyl)methane omega-(Trifluoroacetyl)acetophenone w-(Trifluoroacetyl)acetophenone BENZOYL-1,1,1-TRIFLUOROACETONE LABOTEST-BB LT00005189 AKOS MSC-0330 4,4,4-TRIFLUORO-1-PHENYL-1,3-BUTANEDIONE 1-Phenyl-4,4,4-trifluorobutane-1,3-dione, 2,4-Dioxo-4-phenyl-1,1,1-trifluorobutane Celecoxib Impurity 35 4,4,4-Trifluoro-1-phenylbutane-1,3-dione, 98%, for synthesis 4,4,4-Trifluoro-1-phenyl-1,3-butanedione > 1,3-Butanedione, 4,4,4-trifluoro-1-phenyl- 4,4,4-TRIFLUORO-1-PHENYLBUTANE-1,3-DIONE BENZOYLTRIFLUOROACETONE 326-06-7 C6H5COCH2COCF3 Organic Building Blocks Ketones KETONE Building Blocks C10 Carbonyl Compounds organofluorine compounds Miscellaneous