ChemicalBook >> CAS DataBase List >>Aprepitant Impurity 9

Aprepitant Impurity 9

CAS No.
219821-37-1
Chemical Name:
Aprepitant Impurity 9
Synonyms
Aprepitant Impurity 9;Aprepitant Impurity 47;Fosaprepitant Impurity U;Aprepitant open ring methyl ester;Aprepitant Open-Ring Methyl Ester Impurity;Aprepitant impurity 22/Aprepitant Open-Ring Methyl Ester Impurity;Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholino)-1-iminoethyl)hydrazinecarboxylate;methyl 2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate;2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylic acid methyl ester;Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester
CBNumber:
CB53358992
Molecular Formula:
C24H25F7N4O4
Molecular Weight:
566.47
MDL Number:
MOL File:
219821-37-1.mol
Last updated:2023-05-15 10:44:00
Product description Number Pack Size Price
N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant 457392 1mg $418
N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant 457392 10mg $1890
N-(Destriazolonomethyl) N-(methylcarboxyacetamidohydrazono) aprepitant UIA82137 5mg $873.25
N-(Destriazolonomethyl) N-(methylcarboxyacetamidohydrazono) aprepitant UIA82137 10mg $1397.1
N-(Destriazolonomethyl) N-(methylcarboxyacetamidohydrazono) aprepitant UIA82137 25mg $2278

Aprepitant Impurity 9 Properties

Density 1.43±0.1 g/cm3(Predicted)
solubility soluble in Chloroform, Dichloromethane, Methanol
pka 7.86±0.43(Predicted)
form Solid
color Pale-Yellow
FDA UNII TQ265G4AMC

Aprepitant Impurity 9 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 457392 N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant 219821-37-1 1mg $418 2026-06-03 Buy
Usbiological 457392 N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant 219821-37-1 10mg $1890 2026-06-03 Buy
Biosynth UIA82137 N-(Destriazolonomethyl) N-(methylcarboxyacetamidohydrazono) aprepitant 219821-37-1 5mg $873.25 2026-06-05 Buy
Biosynth UIA82137 N-(Destriazolonomethyl) N-(methylcarboxyacetamidohydrazono) aprepitant 219821-37-1 10mg $1397.1 2026-06-05 Buy
Biosynth UIA82137 N-(Destriazolonomethyl) N-(methylcarboxyacetamidohydrazono) aprepitant 219821-37-1 25mg $2278 2026-06-05 Buy
Product number Packaging Price Buy
457392 1mg $418 Buy
457392 10mg $1890 Buy
UIA82137 5mg $873.25 Buy
UIA82137 10mg $1397.1 Buy
UIA82137 25mg $2278 Buy

Aprepitant Impurity 9 Chemical Properties,Uses,Production

Uses

N-(Destriazolonomethyl), N-(Methylcarboxyacetamidohydrazono) Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1.

Aprepitant Impurity 9 Preparation Products And Raw materials

Raw materials

Preparation Products

Aprepitant Impurity 9 Suppliers

Global( 40)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14332 58
BOC Sciences
16314854226; +16314854226 inquiry@bocsci.com United States 19853 58
Labnetwork lnc.
+86-27-50766799 +8618062016861 contact@labnetwork.com China 19987 58
Moxin Chemicals
+86-17320513646 +8617320513646 anna@molcoo.com China 10000 58
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.
+undefined18603013401 jack.lin@sincopharmachem.com China 10000 58
QUALITY CONTROL SOLUTIONS LTD.
+86-0755-66853366 +8613670046396 export03@qcsrm.com China 24342 58
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18190 56
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9906 50
Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 15250997978 1511893459@qq.com China 4850 55
BOC Sciences 16314854226 info@bocsci.com United States 9923 65
Aprepitant Impurity 9 Aprepitant Open-Ring Methyl Ester Impurity 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylic acid methyl ester Aprepitant impurity 22/Aprepitant Open-Ring Methyl Ester Impurity Aprepitant Impurity 47 Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholino)-1-iminoethyl)hydrazinecarboxylate Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester methyl 2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate Fosaprepitant Impurity U Aprepitant open ring methyl ester 219821-37-1 C24H25F7N4O4