ChemicalBook >> CAS DataBase List >>2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol

2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol

2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol structure

CAS No.: 1898283-02-7

Chemical Name:: 2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol

Synonyms: CS-2805;LY-3200882;LY 3200882 ，S8772;LY-3200882 (LY3200882);LY3200882, 10 mM in DMSO;2-[4-[[4-[1-cyclopropyl-3-(oxan-4-yl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]propan-2-ol;2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol;4-[[4-[[1-Cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]oxy]-2-pyridinyl]amino]-α,α-dimethyl-2-pyridinemethanol;2-Pyridinemethanol, 4-[[4-[[1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]oxy]-2-pyridinyl]amino]-α,α-dimethyl-;2-(4-((4-((1-Cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol?, LY3200882

CBNumber:: CB53364432

Molecular Formula:: C24H29N5O3

Molecular Weight:: 435.52

MDL Number:: MFCD31619238

MOL File:: 1898283-02-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:14:52

Product description	Number	Pack Size	Price
LY3200882 ≥95%	25276	1mg	$41
LY3200882 ≥95%	25276	5mg	$178
LY3200882 ≥95%	25276	10mg	$312
LY3200882 ≥95%	25276	25mg	$680
LY3200882 ≥95%	25276	1mg	$37
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2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol Properties

Boiling point	607.2±55.0 °C(Predicted)
Density	1.36±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO:108.5(Max Conc. mg/mL);249.12(Max Conc. mM)
form	A crystalline solid
pka	13.45±0.29(Predicted)
color	Off-white to light yellow
FDA UNII	19HY34R6UN

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol price More Price(42)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	25276	LY3200882 ≥95%	1898283-02-7	1mg	$41	2026-04-30	Buy
Cayman Chemical	25276	LY3200882 ≥95%	1898283-02-7	5mg	$178	2026-04-30	Buy
Cayman Chemical	25276	LY3200882 ≥95%	1898283-02-7	10mg	$312	2026-04-30	Buy
Cayman Chemical	25276	LY3200882 ≥95%	1898283-02-7	25mg	$680	2026-04-30	Buy
Cayman Chemical	25276	LY3200882 ≥95%	1898283-02-7	1mg	$37	2024-03-01	Buy

Product number	Packaging	Price	Buy
25276	1mg	$41	Buy
25276	5mg	$178	Buy
25276	10mg	$312	Buy
25276	25mg	$680	Buy
25276	1mg	$37	Buy

2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol Chemical Properties,Uses,Production

Uses

4-[[4-[[1-Cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]oxy]-2-pyridinyl]amino]-α,α-dimethyl-2-pyridinemethanol is used to prepare aminopyridyloxypyrazole compounds as TGFβR1 inhibitors.

in vivo

LY3200882 (60 mg/kg; oral gavage; twice a day; for 21 days; BALB/C female mice) treatment significantly delays tumor growth in CT26 model^[2].
LY3200882 potently inhibits TGFβ mediated SMAD phosphorylation in vivo in subcutaneous tumors in a dose dependent fashion^[1].
LY3200882 has shown anti-metastatic activity in vivo in an experimental metastasis tumor model (intravenous EMT6-LM2 model of triple negative breast cancer)^[1].

Animal Model:	BALB/C female mice (5-8-week-old) injected with CT26 cells^[2]
Dosage:	60 mg/kg
Administration:	Oral gavage; twice a day; for 21 days
Result:	A statistically significant tumor growth delay in CT26 model was observed.

2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol Suppliers

Global( 98)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	965	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Chemia Biotechnology（Shanghai） Co., Ltd	+8613816753574	info@chemia-pharm.com	CHINA	311	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471;	sales@sarms4muscle.com	China	10473	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	24597	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39040	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Biochempartner	58
career henan chemical co	58
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Chemia Biotechnology（Shanghai） Co., Ltd	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
HANGZHOU LEAP CHEM CO., LTD.	58
TargetMol Chemicals Inc.	58

View Lastest Price from 2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-05-11	LY3200882 1898283-02-7	$39.00-147.00		99.63%	10g	TargetMol Chemicals Inc.
	2020-01-01	2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol 1898283-02-7	$1.00	1KG	99%	500kg	Career Henan Chemical Co

LY3200882
1898283-02-7
$39.00-147.00
99.63%
TargetMol Chemicals Inc.

2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol
1898283-02-7
$1.00
99%
Career Henan Chemical Co

2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol Spectrum

2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol(1898283-02-7)¹HNMR

1898283-02-7(2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol)Related Search:

LY 294002 Hydrochloride LY-2940094 LY2828360 LY-2562175 LY2228820

Etalocib LY2584702 LY 2784544 LY2409881 trihydrochloride LY-364947

LY 88074 (S)-3-fluoro-4-(4-((2-(3-fluorophenyl)pyrrolidin-1-yl)methyl)phenoxy)benzamide LY-3177833 LY3214996 LY2409881

Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2 LY3023414 LY2955303

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2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol LY-3200882 2-[4-[[4-[1-cyclopropyl-3-(oxan-4-yl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]propan-2-ol CS-2805 2-Pyridinemethanol, 4-[[4-[[1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]oxy]-2-pyridinyl]amino]-α,α-dimethyl- 4-[[4-[[1-Cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]oxy]-2-pyridinyl]amino]-α,α-dimethyl-2-pyridinemethanol Anti-cancer,ALK5,TGFβRI,ATP-competitive,inhibit,immune,phosphorylation,Transforming growth factor beta receptors,anti-metastatic,LY 3200882,TGF-β Receptor,LY-3200882,SMAD,serine-threonine,LY3200882,Inhibitor LY-3200882 (LY3200882) LY3200882, 10 mM in DMSO 2-(4-((4-((1-Cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol?, LY3200882 LY 3200882 ，S8772 1898283-02-7