N-Mal-N-bis(PEG4-acid)
- CAS No.
- 2100306-52-1
- Chemical Name:
- N-Mal-N-bis(PEG4-acid)
- Synonyms
- N-Mal-N-bis(PEG4-acid);Mal-N-bis(PEG4-C2-acid);Acid-apeg8-acid n-c3-maleimide;16-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoyl)-4,7,10,13,19,22,25,28-octaoxa-16-azahentriacontanedioic acid;4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 16-[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-
- CBNumber:
- CB53373746
- Molecular Formula:
- C29H48N2O15
- Molecular Weight:
- 664.7
- MDL Number:
- MFCD29912655
- MOL File:
- 2100306-52-1.mol
- MSDS File:
- SDS
N-Mal-N-bis(PEG4-acid) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0114301 | Mal-N-bis(PEG4-C2-acid) ≥98% | 2100306-52-1 | 250mg | $969 | 2026-06-04 | Buy |
| BroadPharm | bp-23654 | N-Mal-N-bis(PEG4-acid) 98% | 2100306-52-1 | 100MG | $310 | 2026-05-24 | Buy |
| BroadPharm | bp-23654 | N-Mal-N-bis(PEG4-acid) 98% | 2100306-52-1 | 250MG | $550 | 2026-05-24 | Buy |
| BroadPharm | bp-23654 | N-Mal-N-bis(PEG4-acid) 98% | 2100306-52-1 | 500MG | $820 | 2026-05-24 | Buy |
| aablocks | AA019EB8 | 16-[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-4,7,10,13,19,22,25,28-octaoxa-16-azahentriacontanedioic acid 95% | 2100306-52-1 | 50mg | $248 | 2026-05-29 | Buy |
N-Mal-N-bis(PEG4-acid) Chemical Properties, Uses, Production
Description
N-Mal-N-bis(PEG4-acid) is an Maleimide PEG reagent with two terminal carboxylic acids and a maleimide (Mal) group. Maleimide (Mal) reacts specifically with sulfhydryl groups to form a stable thioether linkage when the pH is between 6.5 and 7.5. The terminal carboxylic acids can conjugate with iamine-containing molecule in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Mal-N-bis(PEG4-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-Mal-N-bis(PEG4-acid) Preparation Products And Raw materials
Raw materials
Preparation Products
N-Mal-N-bis(PEG4-acid) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 54996 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Affinity（Wuhan）Ltd. | 15841022315 | sales@affinitytech.cn | China | 2980 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Shanghai Zhiyun Biotechnology Co., Ltd | 13119135307 | China | 2766 | 58 | |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 38906 | 58 |
View Latest Price from N-Mal-N-bis(PEG4-acid) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-18 | Mal-N-bis(PEG4-C2-acid)
2100306-52-1
|
$95.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-06-07 | N-Mal-N-bis(PEG4-acid)
2100306-52-1
|
250mg | >95.00% | 250mg | Xian confluore Biological Technology Co., Ltd. |
-
- Mal-N-bis(PEG4-C2-acid)
2100306-52-1
- $95.00
- TargetMol Chemicals Inc.
-
- N-Mal-N-bis(PEG4-acid)
2100306-52-1
- $0.00
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
