6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride
- CAS No.
- 20232-39-7
- Chemical Name:
- 6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride
- Synonyms
- Tetrabenazine Impurity 2;1.45 kg;Tetrabenazine Impurity 5;6,7-Dimethoxy-3,4-dihydroisoquinoline, HCl;3,4-Dihydro-6,7-dimethoxy-isoquinoline HCl;6,7-Dimethoxy-3,4-dihydroisoquinolineHClhydrate;6,7-dimethoxy-3,4-dihydroisoquinolinium chloride;3,4-dihydro-6,7-dimethoxy-isoquinolinhydrochloride;3,4-dihydro-6,7-dimethoxyisoquinolinehydrochloride;6,7-DiMethoxy-3,4-dihydroisoquinoline hydrochlorid
- CBNumber:
- CB5338375
- Molecular Formula:
- C11H14ClNO2
- Molecular Weight:
- 227.69
- MDL Number:
- MFCD00143492
- MOL File:
- 20232-39-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 198-202 °C |
|---|---|
| RTECS | NW7625000 |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Pale yellow |
| Water Solubility | soluble |
| InChI | InChI=1S/C11H13NO2.ClH/c1-13-10-5-8-3-4-12-7-9(8)6-11(10)14-2;/h5-7H,3-4H2,1-2H3;1H |
| InChIKey | PQXVEYYRJHMTEV-UHFFFAOYSA-N |
| SMILES | C12CCN=CC=1C=C(OC)C(OC)=C2.Cl |
| FDA UNII | WGL5C66P4J |
6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D4629 | 6,7-Dimethoxy-3,4-dihydroisoquinoline Hydrochloride >98.0%(HPLC)(T) | 20232-39-7 | 1g | $29 | 2026-04-30 | Buy |
| TCI Chemical | D4629 | 6,7-Dimethoxy-3,4-dihydroisoquinoline Hydrochloride >98.0%(HPLC)(T) | 20232-39-7 | 5g | $81 | 2026-04-30 | Buy |
| TRC | TRC-D470630-5G | 6,7-Dimethoxy-3,4-dihydroisoquinoline Hydrochloride Hydrate | 20232-39-7 | 5g | $65 | 2026-06-03 | Buy |
| TRC | TRC-D470630-25G | 6,7-Dimethoxy-3,4-dihydroisoquinoline Hydrochloride Hydrate | 20232-39-7 | 25g | $120 | 2026-06-03 | Buy |
| TRC | TRC-D470630-10G | 6,7-Dimethoxy-3,4-dihydroisoquinoline Hydrochloride Hydrate | 20232-39-7 | 10g | $72 | 2026-06-03 | Buy |
6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride Chemical Properties,Uses,Production
Chemical Properties
light yellow to yellow crystalline powder
Uses
6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride is used in the synthesis of Tetrabenazine (T284000).
Uses
6,7-Dimethoxy-3,4-dihydroisoquinoline is used in the synthesis of Tetrabenazine (T284000).
Synthesis
First, 3,4-dimethoxyphenethylamine (18.1 g, 0.1 mol) and ethyl formate (22.1 g) were added to a 100 mL three-necked flask protected by nitrogen, and the reaction was held at 60 C with stirring for 24 hours. Decompression and concentration to obtain N-(3,4-dimethoxyphenethyl)formamide crude product. The above crude product was dissolved in 180 mL of dichloromethane, phthaloyl dichloride (20.3 g, 0.1 mol) was added, and the reaction was stirred at 20C for 4 h. The solid was gradually precipitated. Cooled to 10 , filtered to obtain 6,7-dimethoxy-3,4-dihydroisoquinoline hydrochloride crude product (mother liquor was washed twice with 50mL water, concentrated to recover dichloromethane, the residue was added to 100mL water, filtered to recover phthalic anhydride). Add the above crude product to isopropanol (180mL), heating to 70 , stirring 0.5-1h until all the solids are dissolved; add activated charcoal 1.8g, 80 continue to stir for 2-3h, 50 keep warm and filtration, filtrate re-warming to 70 , stirring for 0.5h; naturally cooled to 20 , it takes about 2h, filtration to get 6,7-dimethoxy-3,4-dihydroisoquinoline hydrochloride The finished product was 19.0 g. Yield 83%, HPLC purity 99.61%.
6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Vcare PharmaTech Co., Ltd. | 025-58741518 13327700685 | sales@vcarepharmatech.com | China | 281 | 61 |
| Anhui Yuanman Chemical Products Sales Co., Ltd. | +86-13816842796; 13816814028 | xena@yi-mu.com | China | 243 | 58 |
| Suzhou Jinglige Technology Co., Ltd | 18551175068 | jinglige888@163.com | China | 248 | 58 |
| Enlian Biomedical (Chongqing) Co., Ltd. | 023-023-63134718 13983849334 | 1501533472@qq.com | China | 31 | 58 |
| Suzhou aihua pharmaceutical technology Co.,Ltd | 13814852116 13814852116 | 373953886@qq.com | China | 22 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Lastest Price from 6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | 6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride
20232-39-7
|
1kg | 995 | 20mt | Jinan Finer Chemical Co., Ltd | ||
 |
2026-08-20 | 6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride
20232-39-7
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2026-07-22 | 6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride
20232-39-7
|
1kg | 99% | 20MT | Watson Biotechnology Co.,Ltd |
-
- 6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride
20232-39-7
- $0.00
- 995
- Jinan Finer Chemical Co., Ltd
-
- 6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride
20232-39-7
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride
20232-39-7
- 99%
- Watson Biotechnology Co.,Ltd
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