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3,4-Dihydroisoquinoline

3,4-Dihydroisoquinoline Structure
3,4-Dihydroisoquinoline structure
CAS No.
3230-65-7
Chemical Name:
3,4-Dihydroisoquinoline
Synonyms
AKOS 213-252;3,4-DihydroisoquinoL;4-DIHYDROISOQUINOLINE;3,4-Dihydroisoquinoline;Isoquinoline, 3,4-dihydro-;3,4-Dihydroisoquinoline ,97%;3,4-Dihydroisoquinoline >=97.5% (GC);3,4-DIHYDROISOQUINOLINE ISO 9001：2015 REACH
CBNumber:
CB8674610
Molecular Formula:
C9H9N
Molecular Weight:
131.17
MDL Number:
MFCD00033714
MOL File:
3230-65-7.mol
MSDS File:
SDS
Last updated:2026-09-12 18:55:49
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3,4-Dihydroisoquinoline Properties

Melting point 251-254℃
Boiling point 241.8±20.0℃ (760 Torr)
Density 1.05±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 1.6041 (589.3 nm 30℃)
Flash point 91.6±22.6℃
storage temp. 2-8°C
form solid
pka 5.80±0.20(Predicted)
Appearance White to off-white Solid
InChI InChI=1S/C9H9N/c1-2-4-9-7-10-6-5-8(9)3-1/h1-4,7H,5-6H2
InChIKey NKSZCPBUWGZONP-UHFFFAOYSA-N
SMILES C1C2=C(C=CC=C2)CCN=1
FDA UNII 2K2ZCG3PSZ
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H302-H310-H315-H319
Precautionary statements  P262-P280-P301+P312+P330-P302+P352+P310-P305+P351+P338
Hazard Codes  T
Risk Statements  22-24-36/38
Safety Statements  26-36/37-45
RIDADR  UN 2811 6.1 / PGII
WGK Germany  3
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications Acute Tox. 2 Dermal
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2

3,4-Dihydroisoquinoline price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 779385 3,4-Dihydroisoquinoline ≥97.5% (GC) 3230-65-7 1g $168.75 2026-04-30 Buy
Sigma-Aldrich 779385 3,4-Dihydroisoquinoline ≥97.5% (GC) 3230-65-7 5g $1050 2026-04-30 Buy
TCI Chemical D6367 3,4-Dihydroisoquinoline 3230-65-7 200MG $133 2026-04-30 Buy
TCI Chemical D6367 3,4-Dihydroisoquinoline 3230-65-7 1G $400 2026-04-30 Buy
Biosynth DAA23065 3,4-Dihydroisoquinoline 3230-65-7 5g $354 2026-06-04 Buy
Product number Packaging Price Buy
779385 1g $168.75 Buy
779385 5g $1050 Buy
D6367 200MG $133 Buy
D6367 1G $400 Buy
DAA23065 5g $354 Buy

3,4-Dihydroisoquinoline Chemical Properties, Uses, Production

Uses

3,4-Dihydroisoquinoline is derived from 1,2,3,4-Tetrahydroisoquinoline (T293820), which is used as a reagent in the preparation of 4-(1,2,4-oxadiazol-5-yl)piperidine-1-carboxamides as antiproliferative tubulin inhibitors.

Uses

3,4-Dihydroisoquinoline can be used as a reactant to synthesize:

  • 5,6-Dihydro-8H-isoquino[1,2-b]quinazolin-8-one by decarboxylative cyclization reaction with isatoic anhydride using tetrabutylammonium iodide (TBAI).
  • 1-naphtholyl tetrahydroisoquinoline by aza-Friedel-Crafts reaction with various naphthols.
  • 3,4-dihydroisoquinoline pseudo bases, which are employed as starting materials for the preperation of 3-benzazepine derivatives.

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 6567, 1994 DOI: 10.1016/S0040-4039(00)78274-8

3,4-Dihydroisoquinoline synthesis

128-08-5
91-21-4
3230-65-7
Synthesis of 3,4-Dihydroisoquinoline from N-Bromosuccinimide and 1,2,3,4-Tetrahydroisoquinoline

3,4-Dihydroisoquinoline Preparation Products And Raw materials

Raw materials

2-PhenylethylaMine Ethyl formate Formic acid Chloroform polyphosphoric acid
Sodium carbonate 1-(Morpholin-4-yl-phenyl-methyl)-naphthalen-2-ol Formamide, N-(2-phenylethyl)- Isoquinoline, 1,2,3,4-tetrahydro-2-hydroxy- Isoquinoline,3,4-dihydro-, 2-oxide
3-(Trifluoromethyl)benzaldehyde Isoquinoline N-Bromosuccinimide 1,2,3,4-Tetrahydroisoquinoline

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Preparation Products

Praziquantel Diazirino[3,1-a]isoquinoline, 1,3,4,8b-tetrahydro-

3,4-Dihydroisoquinoline Suppliers

Global Suppliers ( 84)
Supplier Tel Email Country ProdList Advantage
Anhui Yongsheng Pharmaceutical Technology Co., Ltd 3307 18017383231 983544897@qq.com China 942 58
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Wuhan Haizheng Industry & Trade Development Co. Ltd 027-8866 0053/88660577/88660578 China 1070 55
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9335 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
ShangHai AmK Pharmaceutical Technology Co., Ltd. 微信 18019252918 18019252918 sale@amkchem.com China 14982 55
Supplier Advantage
Anhui Yongsheng Pharmaceutical Technology Co., Ltd 58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Energy Chemical 61
Adamas Reagent, Ltd. 59
Nanjing Chemlin Chemical Co., Ltd 64
Syntechem Co.,Ltd 57
Wuhan Haizheng Industry & Trade Development Co. Ltd 55
Shanghai Jian Chao Chemical Technology Co., Ltd. 55
Bide Pharmatech Ltd. 60
ShangHai AmK Pharmaceutical Technology Co., Ltd. 55

View Latest Price from 3,4-Dihydroisoquinoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,4-DIHYDROISOQUINOLINE pictures 2026-08-20 3,4-DIHYDROISOQUINOLINE
3230-65-7
 $1.10 1g 99.00% 100 Tons Dideu Industries Group Limited

3,4-Dihydroisoquinoline Spectrum

3,4-DIHYDROISOQUINOLINE(3230-65-7)1HNMR3,4-DIHYDROISOQUINOLINE(3230-65-7)IR1

3230-65-7 (3,4-Dihydroisoquinoline) Related Search:

1-Phenyl-3,4-dihydroisoquinoline 3,4-Dihydro-2H-isoquinolin-1-one 1-[(3,4-Dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxyisoquinoline 6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride 7-Hydroxy-6-methoxy-3,4-dihydroisoquinoline
7-Amino-1,2-dihydroisoquinolin-3-(4H)-one 6-Methoxy-3(2H)-isoquinolinone 6,7-Dimethoxy-3,4-dihydroisoquinoline Isocarbostyril 3,4-Dihydroisoquinoline
tert-Butyl 6-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylate 2-tert-Butyl 6-methyl 3,4-dihydroisoquinoline-2,6(1H)-dicarboxylate 1-Methyl-6,7-dimethoxy-3,4-dihydroisoquinoline tert-Butyl 5-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylate 1-Cyano-2-benzoyl-1,2-dihydroisoquinoline
2-Benzyl-2,3-dihydroisoquinolin-4(1H)-one hydrochloride 7-Amino-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 1-Methyl-6,7-dihydroxy-3,4-dihydroisoquinoline monohydrate

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AKOS 213-252 3,4-Dihydroisoquinoline >=97.5% (GC) 3,4-Dihydroisoquinoline ,97% Isoquinoline, 3,4-dihydro- 3,4-DihydroisoquinoL 3,4-DIHYDROISOQUINOLINE ISO 9001：2015 REACH 4-DIHYDROISOQUINOLINE 3,4-Dihydroisoquinoline 3230-65-7