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Algestone acetophenide

Algestone acetophenide Structure
Algestone acetophenide structure
CAS No.
24356-94-3
Chemical Name:
Algestone acetophenide
Synonyms
droxone;DIHYDROXYPROGESTERONE ACETOPHENIDE;p-dhp;bovitrol;SQ-15101;deladroxone;Acetophenide;Neolutin Depositum;Benzoic progesterone;alphasoneacetophenide
CBNumber:
CB5357071
Molecular Formula:
C29H36O4
Molecular Weight:
448.6
MDL Number:
MFCD00056835
MOL File:
24356-94-3.mol
MSDS File:
SDS
Last updated:2026-04-21 10:31:43
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Algestone acetophenide Properties

Melting point 150-151°
alpha D23 +51° (CHCl3)
Boiling point 477.29°C (rough estimate)
Density 1.0455 (rough estimate)
refractive index 1.4800 (estimate)
storage temp. Refrigerator
solubility Chloroform (Sparingly), Methanol (Slightly)
form Solid
color White to Off-White
CAS DataBase Reference 24356-94-3(CAS DataBase Reference)
FDA UNII OL7KC2O3OT

SAFETY

Risk and Safety Statements

Hazard Codes  Xi

Algestone acetophenide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 260000 Algestone acetophenide ≥99% 24356-94-3 5mg $326 2026-06-03 Buy
Usbiological 260000 Algestone acetophenide ≥99% 24356-94-3 10mg $439 2026-06-03 Buy
Usbiological 260000 Algestone acetophenide ≥99% 24356-94-3 25mg $602 2026-06-03 Buy
Usbiological 260000 Algestone acetophenide ≥99% 24356-94-3 50mg $814 2026-06-03 Buy
Usbiological 260000 Algestone acetophenide ≥99% 24356-94-3 100mg $1238 2026-06-03 Buy
Product number Packaging Price Buy
260000 5mg $326 Buy
260000 10mg $439 Buy
260000 25mg $602 Buy
260000 50mg $814 Buy
260000 100mg $1238 Buy

Algestone acetophenide Chemical Properties,Uses,Production

Synthesis

Using dienolone acetate (Ⅰ) as a raw material and acetone as a solvent, potassium permanganate was added at room temperature under formic acid catalysis for oxidation reaction. After the reaction was completed, the mixture was filtered and concentrated under reduced pressure to obtain compound (Ⅱ). Compound (Ⅱ) was condensed with acetophenone at room temperature in the presence of perchloric acid. After the reaction was completed, the mixture was concentrated under pressure to obtain compound (Ⅲ). Compound (Ⅲ) was hydrolyzed with potassium hydroxide methanol solution at room temperature and concentrated under reduced pressure to obtain 3-acetyl group to yield 3-hydroxyl group (Ⅳ). Compound (Ⅳ) was oxidized with chromium trioxide in methanol solvent, refluxed with toluene for 1 h, and purified by cooling crystallization to obtain the target compound phenylprogesterone (Ⅴ).

Synthetic Process Route Diagram of Algestone acetophenide

Originator

Neolutin Depo, Medici ,Italy ,1982

Uses

Progestin.

Uses

Algestone Acetophenide is a progestational steroid that has been shown to increase the proteins in milk and serum in goats and decrease the weight gain of kids. Algestone Acetophenide is used as an injectable steroid contraceptive in Chile and Mexico.

Definition

ChEBI: Algestone acetophenide is a 16alpha,17alpha-dihydroxyprogesterone acetophenide. It has a role as an anti-inflammatory drug and a synthetic oral contraceptive.

Manufacturing Process

To a suspension of 500 mg of 16α,17α-dihydroxyprogesterone in 25 ml of freshly redistilled acetophenone is added 0.125 ml of 72% perchloric acid and the mixture is agitated at room temperature for one hour. The clear solution is washed with dilute sodium bicarbonate to remove excess acid and the acetophenone layer, after addition of chloroform is separated from the aqueous phase. The organic layer is dried over sodium sulfate and after removal of the chloroform and acetophenone in high vacuum the residue is crystallized from 95% alcohol. The pure acetophenone derivative has a melting point of about 142°C to 144°C.

brand name

Deladroxone (Bristol-Myers Squibb); Droxone (Bristol-Myers Squibb).

Therapeutic Function

Progestin, Contraceptive

Algestone acetophenide Preparation Products And Raw materials

Raw materials

Acetophenone

Preparation Products

Algestone acetophenide Suppliers

Global( 172)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Beijing Yisiyan Technology Research Center 010-56645598 13366904824; bjkaida@163.com China 1596 59
Nanjing Sunlida Biological Technology Co., Ltd. 025-57798810 18652991625 sales@sunlidabio.com China 3223 55
Xunteng International Trading Co.,Limited China Hong Kong 876 55
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Finetech Industry Limited 027-87465837 19945049750 sales@finetechnology-ind.com China 9334 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
TAIYUAN RHF CO.,LTD. 56
Capot Chemical Co., Ltd 66
Chemsky（shanghai）International Co.,Ltd. 50
China DongFan Chemical Co.,LTD 66
Beijing Yisiyan Technology Research Center 59
Nanjing Sunlida Biological Technology Co., Ltd. 55
Xunteng International Trading Co.,Limited 55
Quality Control Solutions Ltd. 56
Finetech Industry Limited 58

View Lastest Price from Algestone acetophenide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Algestone acetophenide pictures 2026-08-25 Algestone acetophenide
24356-94-3
 1KG 0.99 1000KG Shaanxi Xianhe Biotech Co., Ltd
Algestone acetophenide pictures 2026-08-08 Algestone acetophenide
24356-94-3
 1g 99% 100kg Hangzhou ICH Biofarm Co., Ltd
Algestone acetophenide pictures 2026-06-30 Algestone acetophenide
24356-94-3
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd

Algestone acetophenide Spectrum

Algestone acetophenide(24356-94-3)1HNMR

24356-94-3(Algestone acetophenide)Related Search:

4-Nitroacetophenone 2-Bromoacetophenone 2'-Hydroxyacetophenone Medroxyprogesterone Acetate 4'-Methylacetophenone
4'-Hydroxyacetophenone Progesterone 3-Nitroacetophenone Algestone Chalcone
Acetophenone Conjugated Estrogen ACETALDEHYDE DI-N-HEXYL ACETAL CIS-1,2-CYCLOPENTANEDIOL Alphasone acetonide
(S)-Glyceraldehyde acetonide 2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde DIPENTOXYETHANE

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16,17-((1-phenylethylidene)bis(oxy))pregn-4-ene-3,20-dione 16-alpha,17-alpha-dihydroxyprogesteroneacetophenide 16-alpha,17-dihydroxypregn-4-ene-3,20-dionecyclicacetalwithacetophenone 17-((1-phenylethylidene)bis(oxy))-20-dion(16-alpha(r))-pregn-4-ene-16 20-dione,16-alpha,17-dihydroxy-pregn-4-ene-cyclicacetalwithacetophenone 3,5-DIETHYL-1,2 DIHYDRO-1-PHENYL-2-PROPYLPYRIDINE (PDHP) alphasoneacetophenide bovitrol deladroxone p-dhp 4-PREGNEN-16-ALPHA, 17-DIOL-3,20-DIONE ACETOPHENIDE 4-PREGNEN-16ALPHA,17ALPHA-DIOL-3,20-DIONE 16,17-ACETOPHENIDE ALGESTONE ACETOPHENIDE (16alpha(r))-16,17-((1-phenylethylidene)bis(oxy))-pregn-4-ene-3,20-dione (R)-16alpha,17-[(1-phenylethylidene)dioxy]pregn-4-ene-3,20-dione 16α,17-Dihydroxyprogesterone acetophenide Neolutin Depositum Pregn-4-ene-3,20-dione, 16,17-[[(1R)-1-phenylethylidene]bis(oxy)]-, (16a)- Pregn-4-ene-3,20-dione, 16a,17-dihydroxy-, cyclic acetal with acetophenone, (R)- 16α,17-[[(R)-1-Phenylethylidene]bis(oxy)]pregn-4-ene-3,20-dione SQ-15101 Algestone acetophonide Algestone acetophenide (16alpha(R))-16,17-((1-Phenylethylidene)bis(oxy))-pregn-4-ene-3,20-dione Benzoic progesterone Pregn-4-ene-3,20-dione, 16,17-[[(1R)-1-phenylethylidene]bis(oxy)]-, (16α)- Acetophenide Algestone acetophenide Estrogen Hormone Raw Powder 4-PREGNEN-16α, 17-DIOL-3, 20-DIONE ACETOPHENIDE Algestone acetophenide, 10 mM in DMSO DIHYDROXYPROGESTERONE ACETOPHENIDE droxone 24356-94-3 56-94-3 34562-31-2 C29H36O4