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Rhodamine B hydrazide

CAS No.
74317-53-6
Chemical Name:
Rhodamine B hydrazide
Synonyms
RhodaMine B Cu2+ sensor;Rhodamine B hydrazide;2-AMINO-3',6'-BIS(DIETHYLAMINO)SPIRO[ISOINDOLE-1,9'-XANTHENE]-3-ONE;2-amino-3',6'-bis(diethylamino)spiro[isoindole-3,9'-xanthene]-1-one;2-Amino-3',6'-bis(diethylamino)spiro[isoindoline-1,9'-xanthen]-3-one;Spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one, 2-aMino-3',6'-bis(diethylaMino)-
CBNumber:
CB5375912
Molecular Formula:
C28H32N4O2
Molecular Weight:
456.58
MDL Number:
MFCD07808762
MOL File:
74317-53-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:53:31

Rhodamine B hydrazide Properties

Melting point 176-177 °C
Boiling point 643.3±65.0 °C(Predicted)
Density 1.27±0.1 g/cm3(Predicted)
solubility DMF: 30 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 20 mg/ml; Ethanol: 0.1 mg/ml
form A crystalline solid
pka 6.44±0.20(Predicted)
color Off-white to yellow
InChI InChI=1S/C28H32N4O2/c1-5-30(6-2)19-13-15-23-25(17-19)34-26-18-20(31(7-3)8-4)14-16-24(26)28(23)22-12-10-9-11-21(22)27(33)32(28)29/h9-18H,5-8,29H2,1-4H3
InChIKey WTDHTIVYKKLOTC-UHFFFAOYSA-N
SMILES C12(C3=C(C=C(N(CC)CC)C=C3)OC3=C1C=CC(N(CC)CC)=C3)C1=C(C=CC=C1)C(=O)N2N

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Corrosion (GHS05)
GHS07,GHS05
Signal word  Danger
Hazard statements  H335-H318-H302-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P280-P305+P351+P338-P310-P264-P270-P301+P312-P330-P501
Hazard Codes  Xn
Risk Statements  22-37/38-41
Safety Statements  26-36
WGK Germany  3
HS Code  32049010
NFPA 704
0
3 0

Rhodamine B hydrazide price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical R0260 Rhodamine B Hydrazide 74317-53-6 200MG $80 2026-04-30 Buy
TCI Chemical R0260 Rhodamine B Hydrazide 74317-53-6 1G $240 2026-04-30 Buy
Cayman Chemical 23133 Rhodamine B hydrazide ≥98% 74317-53-6 5mg $36 2026-04-30 Buy
Cayman Chemical 23133 Rhodamine B hydrazide ≥98% 74317-53-6 10mg $63 2026-04-30 Buy
Cayman Chemical 23133 Rhodamine B hydrazide ≥98% 74317-53-6 25mg $110 2026-04-30 Buy
Product number Packaging Price Buy
R0260 200MG $80 Buy
R0260 1G $240 Buy
23133 5mg $36 Buy
23133 10mg $63 Buy
23133 25mg $110 Buy

Rhodamine B hydrazide Chemical Properties, Uses, Production

Uses

Rhodamine B hydrazide is a good probe for sulfite, with colorless and non-fluorescent properties. While the emission is related to the concentration of sulfite (5-800 ng/mL; detection limit=1.4 ng/mL (3σ)). Sulfite reduces dissolved oxygen to yield superoxide radicals, which binds to Rhodamine B hydrazide to form Rhodamine B. Rhodamine B hydrazide gives Rhodamine B-like fluorescence in the presence of sulfite, which is enhanced by Tween 80 surfactant micelles. Rhodamine B hydrazide has an absorption maximum at 554 nm and a fluorescence emission maximum at 574 nm[1].

References

[1] Yang X F, et al. Novel spectrofluorimetric method for the determination of sulfite with rhodamine B hydrazide in a micellar medium[J]. Analytica Chimica Acta, 2002, 456(1): 121-128.

Rhodamine B hydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

Rhodamine B hydrazide Suppliers

Global Suppliers ( 85)
Supplier Tel Email Country ProdList Advantage
Heliosense Biotechnologies,Inc 0592-5667290 18649641090 info@heliosense.com China 98 58
Jinan Kewei Biotechnology Co., LTD 15315592897 xmxingbjlg@163.com China 201 58
Changzhou Yinghao Technology Development Co., Ltd 15151934985 sales@yingsapharm.com China 5452 58
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Chengdu HappySyn Pharmaceutical Technology Co., Ltd. 85114309 18982182443 yangli@happysyn.com China 2297 55
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai ChuangYan Chemical Technology Co., Ltd. 021-11111111 11111111111 546919421@qq.com China 3769 55
Shanghai Xingui Biotechnology Co., Ltd. 15121041756 xingui2022@126.com China 9954 58
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939 shenlinxing@macklin.cn China 15775 55
Spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one, 2-aMino-3',6'-bis(diethylaMino)- 2-amino-3',6'-bis(diethylamino)spiro[isoindole-3,9'-xanthene]-1-one 2-AMINO-3',6'-BIS(DIETHYLAMINO)SPIRO[ISOINDOLE-1,9'-XANTHENE]-3-ONE 2-Amino-3',6'-bis(diethylamino)spiro[isoindoline-1,9'-xanthen]-3-one RhodaMine B Cu2+ sensor Rhodamine B hydrazide 74317-53-6 C28H32N4O2