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2-Methyl-5-nitronicotinic acid

2-Methyl-5-nitronicotinic acid Structure
2-Methyl-5-nitronicotinic acid structure
CAS No.
59290-81-2
Chemical Name:
2-Methyl-5-nitronicotinic acid
Synonyms
IFLAB-BB F2124-0617;2-Methyl-5-nitronicotinic acid;2-Methyl-5-nitro-3-pyridinecarboxylic acid;2-methyl-5-nitropyridine-3-carboxylic acid;3-Pyridinecarboxylicacid, 2-Methyl-5-nitro-
CBNumber:
CB5405581
Molecular Formula:
C7H6N2O4
Molecular Weight:
182.13
MDL Number:
MFCD07339171
MOL File:
59290-81-2.mol
MSDS File:
SDS
Last updated:2026-09-12 18:53:31
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2-Methyl-5-nitronicotinic acid Properties

Melting point 215-215.5 °C
Boiling point 370.1±42.0 °C(Predicted)
Density 1.477±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 2.47±0.10(Predicted)
Appearance Light brown to brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H335-H315-H302
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501
Hazard Codes  Xi
HazardClass  IRRITANT

2-Methyl-5-nitronicotinic acid price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 027200 2-Methyl-5-nitronicotinic acid 59290-81-2 250.00mg $49 2026-05-18 Buy
Matrix Scientific 027200 2-Methyl-5-nitronicotinic acid 59290-81-2 1.00g $59 2026-05-18 Buy
Matrix Scientific 027200 2-Methyl-5-nitronicotinic acid 59290-81-2 5.00g $282 2026-05-18 Buy
Synthonix M12906 2-Methyl-5-nitronicotinic acid 95+% 59290-81-2 100mg $55 2026-05-06 Buy
Synthonix M12906 2-Methyl-5-nitronicotinic acid 95+% 59290-81-2 250mg $59 2026-05-06 Buy
Product number Packaging Price Buy
027200 250.00mg $49 Buy
027200 1.00g $59 Buy
027200 5.00g $282 Buy
M12906 100mg $55 Buy
M12906 250mg $59 Buy

2-Methyl-5-nitronicotinic acid Chemical Properties, Uses, Production

Synthesis

ETHYL 2-METHYL-5-NITRONICOTINATE

51984-71-5

2-METHYL-5-NITRONICOTINIC ACID

59290-81-2

General procedure for the synthesis of 2-methyl-5-nitronicotinic acid from ethyl 2-methyl-5-nitronicotinate: compound D4 (300 g, 1.4 mol) was dissolved in a mixture of 800 mL hydrochloric acid and 800 mL water. The reaction mixture was heated under reflux conditions for 1 hour. Upon completion of the reaction, it was cooled to room temperature, the reaction solution was diluted with 2.0 L of water and slowly neutralized with the addition of solid sodium bicarbonate to pH=5.0. During this process, a precipitate was gradually formed. The mixture was further cooled and the precipitate was collected by filtration. After drying, brown solid D5 (223 g, 85.7% yield) was obtained. The product was characterized by 1H NMR (DMSO-d6, 300 MHz): δ = 2.84 (s, 3H), 8.74-8.75 (d, 1H), 9.35-9.36 (d, 1H), 13.90 (s, 1H).LC-MS analysis showed that the [M-1]+ peak was located at 180.9.

References

[1] Patent: WO2008/88881, 2008, A1. Location in patent: Page/Page column 33-34
[2] Journal of the American Chemical Society, 1953, vol. 75, p. 737
[3] Patent: WO2007/56016, 2007, A2. Location in patent: Page/Page column 105

2-Methyl-5-nitronicotinic acid Preparation Products And Raw materials

Raw materials

Ethyl 2-methyl-5-nitronicotinate

Preparation Products

tert-Butyl (6-Methyl-5-nitropyridin-3-yl)carbaMate

2-Methyl-5-nitronicotinic acid Suppliers

Global Suppliers ( 72)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Shangchem Co., Ltd. +86-21-68182121 China 881 52
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
skychemical Co.Ltd 021-20958197 20965099 sales@skychemical.com China 1182 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Chiba Pharmaceutical Science and technology Co, Ltd. 0531-81313138 13066006660 chibapharm@foxmail.com China 3996 55
SynAsst Chemical. 021-60343070 China 12731 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Worldyang Chemical Co.,Ltd. 021-56795766 sales@worldyachem.com China 9475 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Shangchem Co., Ltd. 52
Pure Chemistry Scientific Inc. 62
Shandong Xiya Chemical Co., Ltd 57
skychemical Co.Ltd 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Chiba Pharmaceutical Science and technology Co, Ltd. 55
SynAsst Chemical. 55
Bide Pharmatech Ltd. 60
Shanghai Worldyang Chemical Co.,Ltd. 58

View Latest Price from 2-Methyl-5-nitronicotinic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-METHYL-5-NITRONICOTINIC ACID pictures 2020-01-03 2-METHYL-5-NITRONICOTINIC ACID
59290-81-2
 $6.60 1KG 97%-99% 1kg -1000kg Career Henan Chemical Co

2-Methyl-5-nitronicotinic acid Spectrum

2-METHYL-5-NITRONICOTINIC ACID(59290-81-2)1HNMR

59290-81-2 (2-Methyl-5-nitronicotinic acid) Related Search:

Nicotinic acid Ethyl 2-ethyl-5-nitronicotinate Ethyl 5-nitro-2-propylnicotinate Ethyl 2-methyl-5-nitronicotinate 2-Methyl-5-nitronicotinic acid
5,6-Dimethyl-pyridin-3-ylamine 5-Nitronicotinic acid

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2-Methyl-5-nitro-3-pyridinecarboxylic acid 3-Pyridinecarboxylicacid, 2-Methyl-5-nitro- 2-methyl-5-nitropyridine-3-carboxylic acid IFLAB-BB F2124-0617 2-Methyl-5-nitronicotinic acid 59290-81-2 Heterocycle-Pyridine series