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ETHYL 2-METHYL-5-NITRONICOTINATE

CAS No.
51984-71-5
Chemical Name:
ETHYL 2-METHYL-5-NITRONICOTINATE
Synonyms
ETHYL 2-METHYL-5-NITRONICOTITE;ETHYL 2-METHYL-5-NITRONICOTINATE;2-Methyl-5-nitro-nicotinic acid ethyl ester;ethyl 2-Methyl-5-nitropyridine-3-carboxylate;Ethyl 2-methyl-5-nitro-3-pyridinecarboxylate;Pyridinecarboxylicacid,2-Methyl-5-nitro-,ethylester;3-Pyridinecarboxylicacid, 2-Methyl-5-nitro-, ethyl ester
CBNumber:
CB9263479
Molecular Formula:
C9H10N2O4
Molecular Weight:
210.19
MDL Number:
MFCD00753850
MOL File:
51984-71-5.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:47
Product description Number Pack Size Price
Ethyl 2-methyl-5-nitro-3-pyridinecarboxylate 072202 250.00mg $231
Ethyl 2-methyl-5-nitro-3-pyridinecarboxylate 072202 1.00g $500
Ethyl 2-methyl-5-nitro-3-pyridinecarboxylate 072202 5.00g $1340
Ethyl 2-methyl-5-nitronicotinate 95+% E15191 1g $26
Ethyl 2-methyl-5-nitronicotinate 95+% E15191 250mg $30
More product size

ETHYL 2-METHYL-5-NITRONICOTINATE Properties

Melting point 64-65 °C
Boiling point 309.6±37.0 °C(Predicted)
Density 1.272±0.06 g/cm3(Predicted)
storage temp. Store at room temperature
pka -0.02±0.20(Predicted)
Appearance White to yellow Solid

ETHYL 2-METHYL-5-NITRONICOTINATE price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 072202 Ethyl 2-methyl-5-nitro-3-pyridinecarboxylate 51984-71-5 250.00mg $231 2026-05-18 Buy
Matrix Scientific 072202 Ethyl 2-methyl-5-nitro-3-pyridinecarboxylate 51984-71-5 1.00g $500 2026-05-18 Buy
Matrix Scientific 072202 Ethyl 2-methyl-5-nitro-3-pyridinecarboxylate 51984-71-5 5.00g $1340 2026-05-18 Buy
Synthonix E15191 Ethyl 2-methyl-5-nitronicotinate 95+% 51984-71-5 1g $26 2026-05-06 Buy
Synthonix E15191 Ethyl 2-methyl-5-nitronicotinate 95+% 51984-71-5 250mg $30 2026-05-06 Buy
Product number Packaging Price Buy
072202 250.00mg $231 Buy
072202 1.00g $500 Buy
072202 5.00g $1340 Buy
E15191 1g $26 Buy
E15191 250mg $30 Buy

ETHYL 2-METHYL-5-NITRONICOTINATE Chemical Properties,Uses,Production

Synthesis

NITROMALONALDEHYDE

609-32-5

ETHYL 3-AMINOCROTONATE

626-34-6

ETHYL 2-METHYL-5-NITRONICOTINATE

51984-71-5

General procedure for the synthesis of ethyl 2-methyl-5-nitronicotinate from nitromalonaldehyde and ethyl 3-aminocrotonate: nitromalonaldehyde (416 g, 3.6 mol) and ethyl 3-aminocrotonate (339 g, 2.6 mol) were added to a solvent mixture consisting of ethanol (1.9 L), water (1.9 L) and glacial acetic acid (240 mL). The reaction mixture was stirred and reacted at 50 °C overnight. Upon completion of the reaction, the reaction solution was concentrated by distillation under reduced pressure. The concentrated residue was dissolved in dichloromethane (5.0 L) and filtered to remove insoluble matter. The filtrate was concentrated and purified by column chromatography (eluent ratio: ethyl acetate:petroleum ether = 1:10) to afford the target product ethyl 2-methyl-5-nitronicotinate (165 g, 30% yield) as a white solid. The product was characterized by 1H NMR (CDCl3, 300 MHz): δ= 1.23-1.26 (t, 3H), 2.25 (s, 3H), 4.14-4.21 (q, 2H), 8.91-8.92 (t, 1H), 9.37-9.38 (d, 1H).LC-MS analysis showed that the [M + 1]+ peak was located at 210.2.

References

[1] Patent: WO2008/88881, 2008, A1. Location in patent: Page/Page column 33-34

ETHYL 2-METHYL-5-NITRONICOTINATE Preparation Products And Raw materials

Global( 121)Suppliers
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ATK CHEMICAL COMPANY LIMITED
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+86-0571-88938639 +8617705817739 info@dycnchem.com China 52705 58

View Lastest Price from ETHYL 2-METHYL-5-NITRONICOTINATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ETHYL 2-METHYL-5-NITRONICOTINATE pictures 2025-04-04 ETHYL 2-METHYL-5-NITRONICOTINATE
51984-71-5
1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
ETHYL 2-METHYL-5-NITRONICOTINATE pictures 2019-12-26 ETHYL 2-METHYL-5-NITRONICOTINATE
51984-71-5
$2.00 1KG 98%MIN Career Henan Chemical Co

ETHYL 2-METHYL-5-NITRONICOTINATE Spectrum

Ethyl 2-methyl-5-nitro-3-pyridinecarboxylate Pyridinecarboxylicacid,2-Methyl-5-nitro-,ethylester 2-Methyl-5-nitro-nicotinic acid ethyl ester ETHYL 2-METHYL-5-NITRONICOTINATE ethyl 2-Methyl-5-nitropyridine-3-carboxylate 3-Pyridinecarboxylicacid, 2-Methyl-5-nitro-, ethyl ester ETHYL 2-METHYL-5-NITRONICOTITE 51984-71-5 Heterocycle-Pyridine series