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1-Boc-4-(4-bromo-benzoyl)-piperidine

1-Boc-4-(4-bromo-benzoyl)-piperidine Structure
1-Boc-4-(4-bromo-benzoyl)-piperidine structure
CAS No.
439811-37-7
Chemical Name:
1-Boc-4-(4-bromo-benzoyl)-piperidine
Synonyms
1-Boc-4-(4-bromo-benzoyl)-piperidine;tert-butyl 4-(4-broMobenzoyl)piperidine-1-carboxylate;tert-butyl 4-[(4-broMophenyl)carbonyl]piperidine-1-carboxylate;4-(4-bromobenzoyl)piperidine-1-carboxylic acid tert-butyl ester;1-Piperidinecarboxylic acid, 4-(4-bromobenzoyl)-, 1,1-dimethylethyl ester
CBNumber:
CB5413232
Molecular Formula:
C17H22BrNO3
Molecular Weight:
368.27
MDL Number:
MFCD04114991
MOL File:
439811-37-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:53:31
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1-Boc-4-(4-bromo-benzoyl)-piperidine Properties

Boiling point 452.3±40.0 °C(Predicted)
Density 1.325±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka -2.47±0.40(Predicted)
Appearance Off-white to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501

1-Boc-4-(4-bromo-benzoyl)-piperidine price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 265866 1-Boc-4-(4-bromo-benzoyl)piperidine Asreported 439811-37-7 50mg $346 2026-06-03 Buy
Usbiological 265866 1-Boc-4-(4-bromo-benzoyl)piperidine Asreported 439811-37-7 100mg $476 2026-06-03 Buy
Usbiological 265866 1-Boc-4-(4-bromo-benzoyl)piperidine Asreported 439811-37-7 250mg $583 2026-06-03 Buy
Usbiological 265866 1-Boc-4-(4-bromo-benzoyl)piperidine Asreported 439811-37-7 500mg $772 2026-06-03 Buy
Usbiological 265866 1-Boc-4-(4-bromo-benzoyl)piperidine Asreported 439811-37-7 1g $1185 2026-06-03 Buy
Product number Packaging Price Buy
265866 50mg $346 Buy
265866 100mg $476 Buy
265866 250mg $583 Buy
265866 500mg $772 Buy
265866 1g $1185 Buy

1-Boc-4-(4-bromo-benzoyl)-piperidine Chemical Properties, Uses, Production

Synthesis

(4-bromophenyl)(piperidin-4-yl)methanone

746550-66-3

Di-tert-butyl dicarbonate

24424-99-5

1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE

439811-37-7

Step 1. Synthesis of tert-butyl 4-(4-bromobenzoyl)-piperidine-1-carboxylate. To a 250 mL round bottom flask was added 4-(4-bromobenzoyl)piperidine (5 g, 20 mmol), tetrahydrofuran (30 mL), water (30 mL), sodium carbonate (10 g, 90 mmol) and di-tert-butyl dicarbonate (4.35 g, 20.0 mmol). The reaction mixture was stirred at room temperature for 2 h and then partitioned with ethyl acetate and water. The aqueous layer was extracted twice with ethyl acetate, the organic phases were combined, washed with brine, dried, filtered and concentrated to give 7.1 g (100% yield) of tert-butyl 4-(4-bromobenzoyl)-piperidine-1-carboxylate.

References

[1] Patent: WO2016/205590, 2016, A1. Location in patent: Paragraph 00596
[2] Patent: WO2013/147711, 2013, A1. Location in patent: Page/Page column 231
[3] Patent: US2014/371199, 2014, A1. Location in patent: Paragraph 0801
[4] Patent: US2005/54628, 2005, A1. Location in patent: Page/Page column 23-24
[5] Patent: US2005/49269, 2005, A1. Location in patent: Page/Page column 12; 21

1-Boc-4-(4-bromo-benzoyl)-piperidine Preparation Products And Raw materials

Raw materials

(4-bromophenyl)(piperidin-4-yl)methanone tert-butyl 4-(2-tosylhydrazono)piperidine-1-carboxylate 4-Bromobenzaldehyde Di-tert-butyl dicarbonate Sodium carbonate
Tetrahydrofuran Water

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Preparation Products

1-Boc-4-(4-bromo-benzoyl)-piperidine Suppliers

Global Suppliers ( 72)
Supplier Tel Email Country ProdList Advantage
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Shanghai Sphchem Co., Ltd. 021-56491756 13512199871 2819742715@qq.com China 3994 55
Chengdu HappySyn Pharmaceutical Technology Co., Ltd. 85114309 18982182443 yangli@happysyn.com China 2284 55
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
Shanghai Yolne Chemical Co., Ltd. 021-62960152 934678158@qq.com China 9886 55
Taizhou Tongxin Bio-Tech Co., Ltd 0523-86818997 18652728585 sales@allyrise.com China 2986 60
Supplier Advantage
Pure Chemistry Scientific Inc. 62
Accela ChemBio Co.,Ltd. 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky（shanghai）International Co.,Ltd. 50
Shanghai Sphchem Co., Ltd. 55
Chengdu HappySyn Pharmaceutical Technology Co., Ltd. 55
Shanghai Topbiochem Technology Co., Ltd 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Shanghai Yolne Chemical Co., Ltd. 55
Taizhou Tongxin Bio-Tech Co., Ltd 60

View Latest Price from 1-Boc-4-(4-bromo-benzoyl)-piperidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE pictures 2020-01-09 1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE
439811-37-7
 $9.80 1g ≥99% 100kg Career Henan Chemical Co
1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE pictures 2020-01-09 1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE
439811-37-7
 $1.00 1KG 95-99% 1ton Career Henan Chemical Co

1-Boc-4-(4-bromo-benzoyl)-piperidine Spectrum

1-BOC-4-(4-BROMO-BENZOYL)-PIPERIDINE(439811-37-7)1HNMR

439811-37-7 (1-Boc-4-(4-bromo-benzoyl)-piperidine) Related Search:

1-Benzhydrylazetane-3-carbonitrile 1-Boc-4-hydroxy-4-(hydroxymethyl)-piperidine 1-Boc-2-phenyl-piperidin-4-one 1-Boc-4-(4-bromo-benzoyl)-piperidine (4-Oxo-4-phenyl-butyl)-carbamic acid tert-butyl ester
(4-bromophenyl)(piperidin-4-yl)methanone 4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester

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tert-butyl 4-(4-broMobenzoyl)piperidine-1-carboxylate tert-butyl 4-[(4-broMophenyl)carbonyl]piperidine-1-carboxylate 1-Piperidinecarboxylic acid, 4-(4-bromobenzoyl)-, 1,1-dimethylethyl ester 4-(4-bromobenzoyl)piperidine-1-carboxylic acid tert-butyl ester 1-Boc-4-(4-bromo-benzoyl)-piperidine 439811-37-7