2-Chloro-3-methoxypyridine
- CAS No.
- 52605-96-6
- Chemical Name:
- 2-Chloro-3-methoxypyridine
- Synonyms
- 2-CHLORO-3-METHOXYPYRIDINE;Pyridine, 2-chloro-3-Methoxy-;2-Chloro-3-methoxypyridine ,98%;2-chloro-3-methoxypyridine(SALTDATA: FREE);2-Chloro-3-methoxypyridine ISO 9001：2015 REACH
- CBNumber:
- CB5482933
- Molecular Formula:
- C6H6ClNO
- Molecular Weight:
- 143.57
- MDL Number:
- MFCD03426022
- MOL File:
- 52605-96-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 90-92°C |
|---|---|
| Boiling point | 210.6±20.0 °C(Predicted) |
| Density | 1.210±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | -0.51±0.10(Predicted) |
| form | crystalline solid |
| color | Light orange |
| Water Solubility | Insoluble in water. |
| BRN | 115568 |
| InChI | InChI=1S/C6H6ClNO/c1-9-5-3-2-4-8-6(5)7/h2-4H,1H3 |
| InChIKey | CCVNZKGBNUPYPG-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC=CC=C1OC |
| CAS DataBase Reference | 52605-96-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335-H302 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36/37/39-37 | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
2-Chloro-3-methoxypyridine price More Price(81)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS21906 | 2-Chloro-3-methoxypyridine 97% | 52605-96-6 | 1g | $20 | 2026-06-04 | Buy |
| Activate Scientific | AS21906 | 2-Chloro-3-methoxypyridine 97% | 52605-96-6 | 5g | $48 | 2026-06-04 | Buy |
| Activate Scientific | AS21906 | 2-Chloro-3-methoxypyridine 97% | 52605-96-6 | 25g | $106 | 2026-06-04 | Buy |
| Activate Scientific | AS21906 | 2-Chloro-3-methoxypyridine 97% | 52605-96-6 | 100g | $252 | 2026-06-04 | Buy |
| Apolloscientific | OR2800 | 2-Chloro-3-methoxypyridine ≥95% | 52605-96-6 | 1g | $21 | 2026-06-04 | Buy |
2-Chloro-3-methoxypyridine Chemical Properties,Uses,Production
Chemical Properties
White to off-white solid
Uses
It is a pharmaceutical raw material and also used in medicine.
Synthesis
6636-78-8
74-88-4
52605-96-6
Step 1: 2-Chloro-3-hydroxypyridine (2.59 g, 20 mmol), iodomethane (2.98 g, 21 mmol) and potassium carbonate (K2CO3, 5.52 g, 40 mmol) were added to N,N-dimethylformamide (DMF, 50 mL). The reaction mixture was stirred at 60 °C for 4 hours. After completion of the reaction, it was cooled to room temperature and the mixture was poured into water and extracted with ethyl acetate. The organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography to afford 2-chloro-3-methoxypyridine (2.58 g, 90% yield). Mass spectrum (ESI) m/z: 144.0 [M + H]+.
References
[1] Patent: CN107286084, 2017, A. Location in patent: Paragraph 0008
[2] European Journal of Organic Chemistry, 2012, # 31, p. 6248 - 6259,12
[3] European Journal of Organic Chemistry, 2012, # 31, p. 6248 - 6259
[4] Patent: EP2952510, 2015, A1. Location in patent: Paragraph 0120
[5] Patent: WO2011/33265, 2011, A1. Location in patent: Page/Page column 107
2-Chloro-3-methoxypyridine Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai yirong biology science and technology co., ltd | 18049974220 | 3060526242@qq.com | China | 999 | 60 |
| Anhui Jianzhu Biotechnology Co., Ltd. | 15855184105 | 3150278607@qq.com | China | 64 | 58 |
| LEADMEDPHARM CO.,LTD | 13674959855 13674959855 | sales@synthontech.com | China | 3025 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
View Lastest Price from 2-Chloro-3-methoxypyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-09 | 2-Chloro-3-methoxypyridine
52605-96-6
|
1kg | 99%min | 1 tons | Shanghai Yongzeng Technology Co.,Ltd | ||
 |
2026-09-02 | 2-Chloro-3-methoxypyridine
52605-96-6
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-20 | 2-Chloro-3-methoxypyridine
52605-96-6
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- 2-Chloro-3-methoxypyridine
52605-96-6
- 99%min
- Shanghai Yongzeng Technology Co.,Ltd
-
- 2-Chloro-3-methoxypyridine
52605-96-6
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 2-Chloro-3-methoxypyridine
52605-96-6
- $1.10
- 99.00%
- Dideu Industries Group Limited
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