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3-(Methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate

3-(Methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate structure

CAS No.: 890409-87-7

Chemical Name:: 3-(Methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate

Synonyms: NO2-SPP-sulfo-Me;3-(Methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate;3-(methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfaneyl)pentanoate;Pentanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 3-(methylsulfonyl)-2,5-dioxo-1-pyrrolidinyl ester

CBNumber:: CB54903476

Molecular Formula:: C15H17N3O8S3

Molecular Weight:: 463.51

MDL Number:: MFCD20226789

MOL File:: 890409-87-7.mol

Last updated:2025-04-17 18:22:24

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3-(Methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate Properties

Boiling point	687.5±65.0 °C(Predicted)
Density	1.59±0.1 g/cm3(Predicted)
pka	-2.22±0.29(Predicted)

3-(Methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
aablocks	AA01EMXL	3-(METHYLSULFONYL)-2,5-DIOXOPYRROLIDIN-1-YL 4-((5-NITROPYRIDIN-2-YL)DISULFANYL)PENTANOATE >96%	890409-87-7	100mg	$1134	2026-05-30	Buy
aablocks	AA01EMXL	3-(METHYLSULFONYL)-2,5-DIOXOPYRROLIDIN-1-YL 4-((5-NITROPYRIDIN-2-YL)DISULFANYL)PENTANOATE >96%	890409-87-7	250mg	$2071	2026-05-30	Buy
aablocks	AA01EMXL	3-(METHYLSULFONYL)-2,5-DIOXOPYRROLIDIN-1-YL 4-((5-NITROPYRIDIN-2-YL)DISULFANYL)PENTANOATE >96%	890409-87-7	500mg	$3083	2026-05-30	Buy
aablocks	AA01EMXL	3-(METHYLSULFONYL)-2,5-DIOXOPYRROLIDIN-1-YL 4-((5-NITROPYRIDIN-2-YL)DISULFANYL)PENTANOATE >96%	890409-87-7	1g	$4602	2026-05-30	Buy
Crysdot	CD35000009	3-(methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate 95+%	890409-87-7	1g	$2426	2026-05-27	Buy

Product number	Packaging	Price	Buy
AA01EMXL	100mg	$1134	Buy
AA01EMXL	250mg	$2071	Buy
AA01EMXL	500mg	$3083	Buy
AA01EMXL	1g	$4602	Buy
CD35000009	1g	$2426	Buy

3-(Methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate Chemical Properties, Uses, Production

Uses

NO2-SPP-sulfo-Me is a cleavable linker that is used for making antibody-drug conjugate (ADC)[1].

IC 50

Disulfide Cleavable Linker; Cleavable Linker

References

[1] Robert J. Lutz, et al.Methods for decreasing ocular toxicity of antibody drug conjugates. WO2012138749A1.

3-(Methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate Preparation Products And Raw materials

Raw materials

Preparation Products

3-(Methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate Suppliers

Global Suppliers ( 11)

Supplier	Tel	Email	Country	ProdList	Advantage
Fan De(Beijing) Biotechnology Co., Ltd.	15911056312	liming@bio-fount.com	China	9718	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3147	58
Affinity（Wuhan）Ltd.	15841022315	sales@affinitytech.cn	China	2980	58
Jilin Chinese Academy of Sciences-yanshen Technology	18143011203	ET-market@chemextension.com	China	38904	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
Henan Mengtai Pharmaceutical Technology Co., Ltd	17634413542	1959525201@qq.com	China	9011	58
Affinity Linkers Ltd.	15841022315 15841022315	sales@affinitytech.cn	China	7039	58

Supplier	Advantage
Fan De(Beijing) Biotechnology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Hangzhou Huarong Pharm Co., Ltd.	58
Affinity（Wuhan）Ltd.	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
TargetMol Chemicals Inc.	58
Henan Mengtai Pharmaceutical Technology Co., Ltd	58
Affinity Linkers Ltd.	58

890409-87-7 (3-(Methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate) Related Search:

SNPB SNPB-sulfo-Me Pentanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester Pentanoic acid, 4-methyl-4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester Butanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester

2,5-Dioxopyrrolidin-1-yl 4-methyl-4-((5-nitropyridin-2-yl)disulfanyl)pentanoate

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3-(Methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate NO2-SPP-sulfo-Me Pentanoic acid, 4-[(5-nitro-2-pyridinyl)dithio]-, 3-(methylsulfonyl)-2,5-dioxo-1-pyrrolidinyl ester 3-(methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfaneyl)pentanoate 890409-87-7