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GW284543

CAS No.
790186-68-4
Chemical Name:
GW284543
Synonyms
GW284543;UNC10225170;GW284543 HCl;GW284543 (UNC10225170);GW284543, 10 mM in DMSO;6,7-Dimethoxy-N-(3-phenoxyphenyl)quinolin-4-amine;4-Quinolinamine, 6,7-dimethoxy-N-(3-phenoxyphenyl)-;Inhibitor,inhibit,GW 284543,GW284543,UNC 10225170,MIA PaCa-2,GW-284543,Mitogen-activated protein kinase kinase,MEK,MAPKK,UNC-10225170,MAP2K
CBNumber:
CB55419749
Molecular Formula:
C23H20N2O3
Molecular Weight:
372.42
MDL Number:
MFCD32067894
MOL File:
790186-68-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:19:04

GW284543 Properties

storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO:67.0(Max Conc. mg/mL);179.9(Max Conc. mM)
form Solid
color Off-white to gray

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

GW284543 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0078813 GW284543 99.94% 790186-68-4 5mg $92 2026-06-04 Buy
ChemScene CS-0078813 GW284543 99.94% 790186-68-4 10mg $141 2026-06-04 Buy
ChemScene CS-0078813 GW284543 99.94% 790186-68-4 50mg $433 2026-06-04 Buy
ChemScene CS-0078813 GW284543 99.94% 790186-68-4 100mg $693 2026-06-04 Buy
Ambeed A1176981 GW284543 98% 790186-68-4 10mg $98 2026-06-05 Buy
Product number Packaging Price Buy
CS-0078813 5mg $92 Buy
CS-0078813 10mg $141 Buy
CS-0078813 50mg $433 Buy
CS-0078813 100mg $693 Buy
A1176981 10mg $98 Buy

GW284543 Chemical Properties,Uses,Production

Uses

GW284543 (UNC10225170) is a selective MEK5 inhibitor. GW284543 reduces pERK5, and decreases endogenous MYC protein[1].

IC 50

MEK5

References

[1] Vaseva AV, et al. KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism. Cancer Cell. 2018 Nov 12;34(5):807-822.e7. DOI:10.1016/j.ccell.2018.10.001

GW284543 Preparation Products And Raw materials

Raw materials

Preparation Products

GW284543 Suppliers

Global( 42)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4861 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9796 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 10000 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9718 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
InvivoChem +1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6378 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58

View Lastest Price from GW284543 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
GW284543 pictures 2026-04-22 GW284543
790186-68-4
$30.00-106.00 99.75% 10g TargetMol Chemicals Inc.
  • GW284543 pictures
  • GW284543
    790186-68-4
  • $30.00-106.00
  • 99.75%
  • TargetMol Chemicals Inc.

GW284543 Spectrum

GW284543 GW284543 (UNC10225170) UNC10225170 4-Quinolinamine, 6,7-dimethoxy-N-(3-phenoxyphenyl)- 6,7-Dimethoxy-N-(3-phenoxyphenyl)quinolin-4-amine Inhibitor,inhibit,GW 284543,GW284543,UNC 10225170,MIA PaCa-2,GW-284543,Mitogen-activated protein kinase kinase,MEK,MAPKK,UNC-10225170,MAP2K GW284543 HCl GW284543, 10 mM in DMSO 790186-68-4