ChemicalBook >> CAS DataBase List >>(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido-

(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido-

CAS No.
945628-66-0
Chemical Name:
(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido-
Synonyms
CET-rG(ibu) Phosphoramidite;S-cEt-G(ibu) phosphoramidite;S-cEt-G(iBu)-CE-Phosphoramidite;(S)-cEt-G(ibu)-3'-CE-phosphoramidite;5’-O-DMTr-cEt-G(iBu) Phosphoramidite;DMT-CET rG (iBu) phosphoramidite monomer;N6-Bz-2'-O-4'-G-Locked-Gr-CET-Phosphoramidite;(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl);(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido-;((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen (1H-imidazol-1-yl)phosphonate
CBNumber:
CB55839756
Molecular Formula:
C46H56N7O9P
Molecular Weight:
881.95
MDL Number:
MOL File:
945628-66-0.mol
MSDS File:
SDS
Last updated:2026-05-28 04:57:32

(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido- Properties

pka 8.68±0.20(Predicted)
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth PO184478 5’-O-DMT cET-N2-isopropylguanosine 3’-OCE amidite 945628-66-0 250mg $687.5 2026-06-04 Buy
ChemScene CS-0628989 5'-ODMT cEt G Phosphoramidite Amidite 99.43% 945628-66-0 100mg $54 2026-06-04 Buy
ChemScene CS-0628989 5'-ODMT cEt G Phosphoramidite Amidite 99.43% 945628-66-0 250mg $108 2026-06-04 Buy
aablocks AA02AP6B (1S,3R,4R,6S,7S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(2-isobutyramido-6-oxo-1H-purin-9(6H)-yl)-6-methyl-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite ≥98%(mixtureofisomers) 945628-66-0 250mg $34 2026-06-02 Buy
ACHEMBLOCK AD282270 5'-ODMT cEt G phosphoramidite (amidite) 95% 945628-66-0 250MG $145 2026-05-27 Buy
Product number Packaging Price Buy
PO184478 250mg $687.5 Buy
CS-0628989 100mg $54 Buy
CS-0628989 250mg $108 Buy
AA02AP6B 250mg $34 Buy
AD282270 250MG $145 Buy

(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido- Chemical Properties, Uses, Production

Uses

5'-ODMT cEt G Phosphoramidite Amidite is a potent nucleic acid analog. 5'-ODMT cEt G Phosphoramidite Amidite shows excellent safety and antisense activity[1][2].

References

[1] Vasquez G, et al. Site-specific incorporation of 5'-methyl DNA enhances the therapeutic profile of gapmer ASOs. Nucleic Acids Res. 2021 Feb 26;49(4):1828-1839. DOI:10.1093/nar/gkab047
[2] Seth PP, et al. Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analogues. J Org Chem. 2010 Mar 5;75(5):1569-81. DOI:10.1021/jo902560f
[3] Vasquez G, et al., Site-specific incorporation of 5'-methyl DNA enhances the therapeutic profile of gapmer ASOs. Nucleic Acids Res. 2021 Feb 26;49(4):1828-1839. DOI:10.1093/nar/gkab047

(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido- Preparation Products And Raw materials

Raw materials

Preparation Products

(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido- Suppliers

Global Suppliers ( 30)
Supplier Tel Email Country ProdList Advantage
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Wuhu Nuowei Chemical Technology Co., Ltd 0553-8233716 18055326116 sales@nuowei-chem.com China 742 55
Hangzhou Dingyan Chem Co., LTD 0571-87157530-8002 15267169049 sales@dingyanchem.com China 2611 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Wuhu Huaren Science and Technology Co., Ltd. 5842013 18155347026 xujuan@hdpharm.com China 547 58
Dideu Industries Group Limited +8617392712697 1022@dideu.com China 29089 58
NewCan Biotech Limited +86-571-86912261 19975279805 sales@newcanbio.com China 9984 58
Beijing xinyanhui pharmaceutical research and development co., LTD 13969155946 1461866103@qq.com China 16103 58
Block Chemical Technology (Shanghai) Co., Ltd. 021-20432219 13918097649 li_jinfei@acblock-lab.com China 10032 58
Wuhan Tangzhi Pharmaceutical Co., Ltd. 027-63498076 13658392159 sale@glycogene.com China 838 58

945628-66-0 ((1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido-) Related Search:

(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido- Propanamide, N-[9-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-6-deoxy-α-L-mannofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methyl- N6-Bz-2'-O-4'-G-Locked-Gr-CET-Phosphoramidite (1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) (1s,3r,4r,6s,7s)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(2-isobutyramido-6-oxo-1h-purin-9(6h)-yl)-6-methyl-2,5-dioxabicyclo[2.2.1]heptan-7-yl 2-cyanoethyl diisopropylphosphoramidite CET-rG(ibu) Phosphoramidite S-cEt-G(iBu)-CE-Phosphoramidite S-cEt-G(ibu) phosphoramidite (S)-cEt-G(ibu)-3'-CE-phosphoramidite DMT-CET rG (iBu) phosphoramidite monomer 5’-O-DMTr-cEt-G(iBu) Phosphoramidite ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen (1H-imidazol-1-yl)phosphonate 945628-66-0 C46H56N7O9P Amidite