(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido-
- CAS No.
- 945628-66-0
- Chemical Name:
- (1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido-
- Synonyms
- CET-rG(ibu) Phosphoramidite;S-cEt-G(ibu) phosphoramidite;S-cEt-G(iBu)-CE-Phosphoramidite;(S)-cEt-G(ibu)-3'-CE-phosphoramidite;5’-O-DMTr-cEt-G(iBu) Phosphoramidite;DMT-CET rG (iBu) phosphoramidite monomer;N6-Bz-2'-O-4'-G-Locked-Gr-CET-Phosphoramidite;(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl);(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido-;((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen (1H-imidazol-1-yl)phosphonate
- CBNumber:
- CB55839756
- Molecular Formula:
- C46H56N7O9P
- Molecular Weight:
- 881.95
- MDL Number:
- MOL File:
- 945628-66-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | PO184478 | 5’-O-DMT cET-N2-isopropylguanosine 3’-OCE amidite | 945628-66-0 | 250mg | $687.5 | 2026-06-04 | Buy |
| ChemScene | CS-0628989 | 5'-ODMT cEt G Phosphoramidite Amidite 99.43% | 945628-66-0 | 100mg | $54 | 2026-06-04 | Buy |
| ChemScene | CS-0628989 | 5'-ODMT cEt G Phosphoramidite Amidite 99.43% | 945628-66-0 | 250mg | $108 | 2026-06-04 | Buy |
| aablocks | AA02AP6B | (1S,3R,4R,6S,7S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(2-isobutyramido-6-oxo-1H-purin-9(6H)-yl)-6-methyl-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite ≥98%(mixtureofisomers) | 945628-66-0 | 250mg | $34 | 2026-06-02 | Buy |
| ACHEMBLOCK | AD282270 | 5'-ODMT cEt G phosphoramidite (amidite) 95% | 945628-66-0 | 250MG | $145 | 2026-05-27 | Buy |
(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido- Chemical Properties, Uses, Production
Uses
5'-ODMT cEt G Phosphoramidite Amidite is a potent nucleic acid analog. 5'-ODMT cEt G Phosphoramidite Amidite shows excellent safety and antisense activity[1][2].
References
[1] Vasquez G, et al. Site-specific incorporation of 5'-methyl DNA enhances the therapeutic profile of gapmer ASOs. Nucleic Acids Res. 2021 Feb 26;49(4):1828-1839. DOI:10.1093/nar/gkab047
[2] Seth PP, et al. Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analogues. J Org Chem. 2010 Mar 5;75(5):1569-81. DOI:10.1021/jo902560f
[3] Vasquez G, et al., Site-specific incorporation of 5'-methyl DNA enhances the therapeutic profile of gapmer ASOs. Nucleic Acids Res. 2021 Feb 26;49(4):1828-1839. DOI:10.1093/nar/gkab047
(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido- Preparation Products And Raw materials
Raw materials
Preparation Products
(1S, 3R, 4R, 6S, 7S) - 1- ((Bis(4- Methoxyphenyl) (Phenyl) Methoxy) Methyl) - 3- (2- Isobutyramido- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Wuhu Nuowei Chemical Technology Co., Ltd | 0553-8233716 18055326116 | sales@nuowei-chem.com | China | 742 | 55 |
| Hangzhou Dingyan Chem Co., LTD | 0571-87157530-8002 15267169049 | sales@dingyanchem.com | China | 2611 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Wuhu Huaren Science and Technology Co., Ltd. | 5842013 18155347026 | xujuan@hdpharm.com | China | 547 | 58 |
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29089 | 58 |
| NewCan Biotech Limited | +86-571-86912261 19975279805 | sales@newcanbio.com | China | 9984 | 58 |
| Beijing xinyanhui pharmaceutical research and development co., LTD | 13969155946 | 1461866103@qq.com | China | 16103 | 58 |
| Block Chemical Technology (Shanghai) Co., Ltd. | 021-20432219 13918097649 | li_jinfei@acblock-lab.com | China | 10032 | 58 |
| Wuhan Tangzhi Pharmaceutical Co., Ltd. | 027-63498076 13658392159 | sale@glycogene.com | China | 838 | 58 |





