Dodeca-2(E),4(E)-dienoic acid isobutylamide(p)
- CAS No.
- 24738-51-0
- Chemical Name:
- Dodeca-2(E),4(E)-dienoic acid isobutylamide(p)
- Synonyms
- 2,4-Dodecadienoic acid isobutylamide;Dienamide A2;DODECA-2(E)-DIENOIC ACID ISOBUTYLAMIDE;(2E,4E)-N-isobutyldodeca-2,4-dienamide;Dodeca-2(E),4(E)-dienoic acid isobutlamide;Dodeca-2(E),4(E)-dienoic acid isobutylamide(p);2,4-Dodecadienamide, N-(2-methylpropyl)-, (2E,4E)-
- CBNumber:
- CB5655029
- Molecular Formula:
- C16H29NO
- Molecular Weight:
- 251.41
- MDL Number:
- MOL File:
- 24738-51-0.mol
| Melting point | 74-75 °C |
|---|---|
| Boiling point | 396.896±15.00 °C(Press: 760.00 Torr)(predicted) |
| Density | 0.878±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (up to 25 mg/ml) on in Ethanol (up to 25 mg/ml) |
| pka | 14.716±0.46(predicted) |
| form | solid |
| color | White |
| Stability | Stable for 1 year from date of purchsae as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
| LogP | 4.962 (est) |
| FDA UNII | 5F4WO3BVS9 |
Dodeca-2(E),4(E)-dienoic acid isobutylamide(p) price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FD171294 | Dodeca-2(E),4(E)-dienoic acid isobutlamide | 24738-51-0 | 5mg | $324.5 | 2026-06-04 | Buy |
| Biosynth | FD171294 | Dodeca-2(E),4(E)-dienoic acid isobutlamide | 24738-51-0 | 25mg | $1168.25 | 2026-06-04 | Buy |
| ChemScene | CS-0146224 | Kalecide 98.61% | 24738-51-0 | 1mg | $182 | 2026-06-04 | Buy |
| aablocks | AA00C4CN | Kalecide >98% | 24738-51-0 | 1mg | $222 | 2026-05-28 | Buy |
| TRC | K445015 | Kalecide | 24738-51-0 | 50mg | $1540 | 2021-12-16 | Buy |
Dodeca-2(E),4(E)-dienoic acid isobutylamide(p) Chemical Properties, Uses, Production
Description
Dienamide A2 (24738-51-0) is an analog of the natural amides occurring in Echinacea which represent a new class of cannabinomimetic compounds. This class of compounds modulates TNFα mRNA expression in human monocytes/macrophages via the CB2 receptor.1Dienamide A2 binds to cannabinoid receptors with greater affinity than endogenous cannabinoids (Ki= ~60 and >1500 nM for CB2 and CB1 respectively)2. It elevates intracellular Ca2+ levels in CB2-positive but not in CB2-negative cells and this effect was blocked by SR144528.2It significantly inhibits LPS-induced TNFα and IL-1β expression in a CB2-independent manner.2
Uses
Kalecide is a natural pesticide of Echinacea angustifolia, Echinacea atrorubens and Piper sarmentosum.
Definition
ChEBI: (2E,4E)-N-isobutyl-2,4-dodecadienamide is a fatty amide. It has a role as a metabolite.
References
[1] JUERG GERTSCH. Echinacea alkylamides modulate TNF-α gene expression via cannabinoid receptor CB2 and multiple signal transduction pathways[J]. FEBS Letters, 2004, 577 3: 563-569. DOI:10.1016/j.febslet.2004.10.064
[2] STEFAN RADUNER. Alkylamides from Echinacea are a new class of cannabinomimetics. Cannabinoid type 2 receptor-dependent and -independent immunomodulatory effects.[J]. The Journal of Biological Chemistry, 2006, 281 20: 14192-14206. DOI:10.1074/jbc.m601074200
Dodeca-2(E),4(E)-dienoic acid isobutylamide(p) Preparation Products And Raw materials
Raw materials
Preparation Products
Dodeca-2(E),4(E)-dienoic acid isobutylamide(p) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Haohong Scientific Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39718 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | rose.shi@synzest.com | China | 6204 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| uchtechcn | 13916276291 | songjinshi@nuchtechcn.com | China | 2069 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 17717235263 | offer.de@lgcgroup.com | China | 38135 | 58 |
| Shaanxi Xihua Chemical Industry Co., Ltd. | 18161915376 | 1096@dideu.com | China | 1316 | 58 |
