1-(CHLOROMETHYL)-3,5-BIS(METHYLSULFONYL)BENZENE
- CAS No.
- 39552-81-3
- Chemical Name:
- 1-(CHLOROMETHYL)-3,5-BIS(METHYLSULFONYL)BENZENE
- Synonyms
- 2-(4-aminophenyl)propanoate;Benzocaine Impurity 14;METHYL P-AMINOPHENYLACETATE;Methyl 4-aminobenzeneacetate;METHYL-(4-AMINOPHENYL)ACETATE;p-(Methoxycarbonylmethyl)aniline;4-Aminophenylacetic acid methyl ester;Benzeneacetic acid, 4-amino-, methyl ester;1-(CHLOROMETHYL)-3,5-BIS(METHYLSULFONYL)BENZENE;1-(CHLOROMETHYL)-3,5-BIS(METHYLSULPHONYL)BENZENE
- CBNumber:
- CB5672534
- Molecular Formula:
- C9H11NO2
- Molecular Weight:
- 165.19
- MDL Number:
- MFCD06200783
- MOL File:
- 39552-81-3.mol
| Product description | Number | Pack Size | Price |
| Methyl 4-aminophenylacetate 98% | OR0171 | 1g | $21 |
| Methyl 4-aminophenylacetate 98% | OR0171 | 5g | $24 |
| Methyl-(4-aminophenyl)acetate | 012593 | 25.00g | $38 |
| Methyl-(4-aminophenyl)acetate | 012593 | 100.00g | $123 |
| Methyl-(4-aminophenyl)acetate | 012593 | 500.00g | $606 |
| Melting point | 197-200°C |
|---|---|
| Boiling point | 96-100/0.07mm |
| Density | 1.143±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| pka | 4.36±0.10(Predicted) |
| form | liquid |
| color | Brown |
| InChI | 1S/C9H11NO2/c1-12-9(11)6-7-2-4-8(10)5-3-7/h2-5H,6,10H2,1H3 |
| InChIKey | TVIVLENJTXGRAM-UHFFFAOYSA-N |
| SMILES | COC(=O)Cc1ccc(N)cc1 |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| Hazard Codes | Xi |
| Risk Statements | 43-52 |
| Safety Statements | 36-37 |
| WGK Germany | WGK 3 |
| HazardClass | IRRITANT |
| HS Code | 2922290090 |
| Storage Class | 11 - Combustible Solids |
1-(CHLOROMETHYL)-3,5-BIS(METHYLSULFONYL)BENZENE price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR0171 | Methyl 4-aminophenylacetate 98% | 39552-81-3 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR0171 | Methyl 4-aminophenylacetate 98% | 39552-81-3 | 5g | $24 | 2026-06-04 | Buy |
| Matrix Scientific | 012593 | Methyl-(4-aminophenyl)acetate | 39552-81-3 | 25.00g | $38 | 2026-05-18 | Buy |
| Matrix Scientific | 012593 | Methyl-(4-aminophenyl)acetate | 39552-81-3 | 100.00g | $123 | 2026-05-18 | Buy |
| Matrix Scientific | 012593 | Methyl-(4-aminophenyl)acetate | 39552-81-3 | 500.00g | $606 | 2026-05-18 | Buy |
1-(CHLOROMETHYL)-3,5-BIS(METHYLSULFONYL)BENZENE Chemical Properties,Uses,Production
Synthesis
67-56-1
1197-55-3
39552-81-3
Synthesis of Intermediate 8a: Methyl 2-(4-aminophenyl)acetate 4-Aminophenylacetic acid (10.0 g, 66.6 mmol) was dissolved in methanol (350 mL), stirred and concentrated. Concentrated sulfuric acid (3.88 mL, 72.77 mmol) was added slowly and dropwise. The reaction mixture was stirred at 50 °C overnight and subsequently cooled to room temperature and concentrated under vacuum. The concentrated mixture was diluted with water, neutralized with sodium carbonate (Na2CO3) until the solid precipitated, and then extracted with dichloromethane (DCM). The organic layer was dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated to give methyl 2-(4-aminophenyl)acetate (9.75 g, 59.02 mmol, 89% yield). Method 2: RT: 0.60 min, m/z 165.9 [M + H]+.
References
[1] Patent: US2014/303218, 2014, A1. Location in patent: Paragraph 0088-0089
[2] Dalton Transactions, 2018, vol. 47, # 15, p. 5259 - 5268
[3] Patent: WO2016/51193, 2016, A1. Location in patent: Paragraph 00249; 00250; 00251
[4] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 6, p. 1784 - 1789
[5] Journal of Medicinal Chemistry, 1997, vol. 40, # 7, p. 1049 - 1062
1-(CHLOROMETHYL)-3,5-BIS(METHYLSULFONYL)BENZENE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1-(CHLOROMETHYL)-3,5-BIS(METHYLSULFONYL)BENZENE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 | CB@aromsyn.com | China | 19183 | 58 |
View Lastest Price from 1-(CHLOROMETHYL)-3,5-BIS(METHYLSULFONYL)BENZENE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-08 | 39552-81-3
39552-81-3
|
1KG | 98%; 99% | 1kg; 10kg; 25kg | Career Henan Chemical Co |
-
- 39552-81-3
39552-81-3
- $0.01
- 98%; 99%
- Career Henan Chemical Co
39552-81-3(1-(CHLOROMETHYL)-3,5-BIS(METHYLSULFONYL)BENZENE)Related Search:
1of4
