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Tetranor-12(S)-hete

Tetranor-12(S)-hete Structure
Tetranor-12(S)-hete structure
CAS No.
121842-79-3
Chemical Name:
Tetranor-12(S)-hete
Synonyms
Tetranor-12(S)-hete;KBOVKDIBOBQLRS-ONCCEEIJSA-N;4,6,10-Hexadecatrienoic acid, 8-hydroxy-, [S-(E,Z,Z)]- (9CI)
CBNumber:
CB5673889
Molecular Formula:
C16H26O3
Molecular Weight:
266.38
MDL Number:
MFCD08457913
MOL File:
121842-79-3.mol
MSDS File:
SDS
Last updated:2026-09-12 18:53:38
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Tetranor-12(S)-hete Properties

storage temp. Store at -20°C
solubility 0.1 M Na2CO3: 2 mg/ml; DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): .5 mg/ml

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

Tetranor-12(S)-hete price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10007207 tetranor-12(S)-HETE ≥98% 121842-79-3 25μg $179 2026-04-30 Buy
Cayman Chemical 10007207 tetranor-12(S)-HETE ≥98% 121842-79-3 50μg $337 2026-04-30 Buy
Cayman Chemical 10007207 tetranor-12(S)-HETE ≥98% 121842-79-3 100μg $636 2026-04-30 Buy
ChemScene CS-0374549 Tetranor-12(S)-HETE 121842-79-3 25μg $386 2026-06-04 Buy
ChemScene CS-0374549 Tetranor-12(S)-HETE 121842-79-3 50μg $729 2026-06-04 Buy
Product number Packaging Price Buy
10007207 25μg $179 Buy
10007207 50μg $337 Buy
10007207 100μg $636 Buy
CS-0374549 25μg $386 Buy
CS-0374549 50μg $729 Buy

Tetranor-12(S)-hete Chemical Properties, Uses, Production

Description

12(S)-HETE is a product of arachidonic acid metabolism through the 12-lipoxygenase pathway. It is primarily found in platelets, leukocytes, and to a lesser extent in smooth muscle cells. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix. tetranor-12(S)-HETE is the major β-oxidation product resulting from peroxisomal metabolism of 12(S)-HETE in numerous tissues, and Lewis lung carcinoma cells. No biological function has yet been determined for tetranor-12(S)-HETE. Some data indicate it may play a role in controlling the inflammatory response in injured corneas. In some diseases (e.g., Zellweger’s Syndrome) peroxisomal abnormalities result in the inability of cells to metabolize 12(S)-HETE, which may be responsible for symptoms of the disease. The tetranor derivative of 12(S)-HETE is available as a research tool for the elucidation of the metabolic fate of its parent compound.

Uses

Tetranor-12(S)-HETE is the major β-oxidation product resulting from peroxisomal metabolism of 12(S)-HETE (HY-124404A) in numerous tissues. 12(S)‐HETE to tetranor‐12(S)‐HETE conversion could be a marker for psoriasis[1].

Definition

ChEBI: Tetranor 12-HETE is a hydroxy fatty acid.

References

[1] Setkowicz M, et al. Lack of association of ALOX12 and ALOX15B polymorphisms with psoriasis despite altered urinary excretion of 12(S)-hydroxyeicosatetraenoic acid. Br J Dermatol. 2015 Feb;172(2):337-44. DOI:10.1111/bjd.13225

Tetranor-12(S)-hete Preparation Products And Raw materials

Raw materials

Preparation Products

Tetranor-12(S)-hete Suppliers

Global Suppliers ( 17)
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
SHANGHAI ZZBIO CO., LTD. 18019219489 18901678489 tech@zzbioco.com China 12062 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
TargetMol Chemicals Inc. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
SHANGHAI ZZBIO CO., LTD. 58

View Latest Price from Tetranor-12(S)-hete manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
tetranor-12(S)-HETE pictures 2026-05-11 tetranor-12(S)-HETE
121842-79-3
 $1980.00 10g TargetMol Chemicals Inc.

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KBOVKDIBOBQLRS-ONCCEEIJSA-N 4,6,10-Hexadecatrienoic acid, 8-hydroxy-, [S-(E,Z,Z)]- (9CI) Tetranor-12(S)-hete 121842-79-3