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H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH

H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH structure

CAS No.: 143413-47-2

Chemical Name:: H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH

Synonyms: (ARG)9;RRRRRRRRR;Poly Arginine 9;Peptide R9;R 9 peptide;Nonaarginine;(Arg)9 peptide;Nona-L-arginine;H-RRRRRRRRR-NH2;R9/Nonaarginine

CBNumber:: CB5706464

Molecular Formula:: C54H110N36O10

Molecular Weight:: 1423.69

MDL Number:: MFCD08458590

MOL File:: 143413-47-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:53:40

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H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH Properties

Density	1.60±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
Sequence	H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH
FDA UNII	PK7O6W0U44

H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	FA109774	H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH trifluoroacetate salt	143413-47-2	50mg	$900	2026-06-04	Buy
Biosynth	FA109774	H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH trifluoroacetate salt	143413-47-2	25mg	$900	2026-06-04	Buy
Biosynth	FA109774	H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH trifluoroacetate salt	143413-47-2	100mg	$1080	2026-06-04	Buy
Biosynth	FA109774	H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH trifluoroacetate salt	143413-47-2	250mg	$1440	2026-06-04	Buy
Biosynth	FA109774	H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH trifluoroacetate salt	143413-47-2	500mg	$1805	2026-06-04	Buy

Product number	Packaging	Price	Buy
FA109774	50mg	$900	Buy
FA109774	25mg	$900	Buy
FA109774	100mg	$1080	Buy
FA109774	250mg	$1440	Buy
FA109774	500mg	$1805	Buy

H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH Chemical Properties, Uses, Production

Uses

(Arg)9 (Nona-L-arginine) is a cell-penetrating peptide (CPP) made up of 9 arginine residues, which is an inhibitor of serine endoprotease Furin. (Arg)9 has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model[1][2].

Biological Activity

(Arg)9 (Nona-L-arginine; Peptide R9) is a cell-permeable polypeptide with IC50 value of 0.78 μM for neuroprotection in a glutamate model experimental model.

in vitro

Poly-arginine (eg (Arg)9) and arginine-rich peptides (eg TAT, penetratin), which belong to a class of peptides with cell-penetrating properties are neuroprotective. It provides significant neuroprotection in a dose–response manner following glutamic acid exposure (IC ₅₀ =0.78 μM). Following kainic acid exposure, (Arg)9 is neuroprotective, but less effective than in the glutamic acid model (IC ₅₀ =0.81 μM). (Arg)9 also shows neuroprotection following in vitro ischemia (IC ₅₀ =6 μM).

in vivo

(Arg)9) (D-isoform) is neuroprotective in rat stroke models. (Arg)9) is highly neuroprotective, with efficacy increasing with increasing arginine content, has the capacity to reduce glutamic acid-induced neuronal calcium influx and requires heparan sulfate preotoglycan-mediated endocytosis to induce a neuroprotective effect. (Arg)9) (D-isoform) administered intravenously at a dose of 1000 nmol/kg 30 min after reduces permanent middle cerebral artery occlusion (MCAO) infarct volume .

target

IC50: 0.78 μM (neuroprotection)

References

[1] Cameron A, et al. Polyarginines are potent furin inhibitors. J Biol Chem. 2000 Nov 24;275(47):36741-9. DOI:10.1074/jbc.M003848200
[2] Meloni BP, et, al. The neuroprotective efficacy of cell-penetrating peptides TAT, penetratin, Arg-9, and Pep-1 in glutamic acid, kainic acid, and in vitro ischemia injury models using primary cortical neuronal cultures. Cell Mol Neurobiol. 2014 Mar;34(2):173-81. DOI:10.1007/s10571-013-9999-3
[3] Meloni BP, et, al. Poly-arginine and arginine-rich peptides are neuroprotective in stroke models. J Cereb Blood Flow Metab. 2015 Jun;35(6):993-1004. DOI:10.1038/jcbfm.2015.11

H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH Preparation Products And Raw materials

Raw materials

Preparation Products

H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH Suppliers

Global Suppliers ( 96)

Supplier	Tel	Email	Country	ProdList	Advantage
Beijing HwrkChemical Technology Co., Ltd	89508211 18501085097	sales.bj@hwrkchemical.com	China	9407	55
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4853	58
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632;	sales@reading-chemicals.com	China	15165	58
Creative Peptides		info@creative-peptides.com	United States	6083	56
Pharmacodia (Beijing) Co.,Ltd	+86-400-851-9921	sales@pharmacodia.com	China	2308	55
Avantpbc Chemical Tech(Shanghai) Co,Ltd.	17802107445		China	185	55
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58

Supplier	Advantage
Beijing HwrkChemical Technology Co., Ltd	55
GL Biochem (Shanghai) Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60
MedChemexpress LLC	58
Wuxi Zhongkun Biochemical Technology Co., Ltd.	58
Creative Peptides	56
Pharmacodia (Beijing) Co.,Ltd	55
Avantpbc Chemical Tech(Shanghai) Co,Ltd.	55
Amadis Chemical Company Limited	58

View Latest Price from H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-05-11	(Arg)9 143413-47-2				10g	TargetMol Chemicals Inc.
	2020-02-14	H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH 143413-47-2	$7.00	1KG	99%	100kg	Career Henan Chemical Co

(Arg)9
143413-47-2
$0.00
TargetMol Chemicals Inc.

H-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-ARG-OH
143413-47-2
$7.00
99%
Career Henan Chemical Co

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(Arg)9, FAM-labeled (Arg)9, TAMRA-labeled H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH

1of4

H-RRRRRRRRR-NH2 Nonaarginine H(-Arg)9-OH, Nonaarginine (Arg)9 peptide Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg Poly Arginine 9|(Arg)9 peptide|RRRRRRRRR Poly Arginine 9|(Arg)9 NJ-Peptide L-Arginine,L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl- Nona-L-arginine Peptide R9 L-Arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginine R 9 peptide (6S,9S,12S,15S,18S,21S,24S,27S,30S)-1,6-Diamino-9,12,15,18,21,24,27,30-octakis(3-guanidinopropyl)-1-imino-7,10,13,16,19,22,25,28-octaoxo-2,8,11,14,17,20,23,26,29-nonaazahentriacontan-31-oic acid R9/Nonaarginine (ARG)9 Poly Arginine 9 RRRRRRRRR H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH 143413-47-2 C54H110N36O10 peptide