(Arg)9 NEW
| Price | Get Latest Price |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-21 |
Product Details
| Product Name: (Arg)9 | CAS No.: 143413-47-2 |
| Supply Ability: 10g | Release date: 2025/08/21 |
Product Introduction
Bioactivity
| Name | (Arg)9 |
| Description | (Arg)9 (Nona-L-arginine;Peptide R9) is a cell-penetrating peptide,and exhibits neuroprotective activity(IC50 of 0.78 μM, in the glutamic acid model). |
| In vitro | Poly-arginine (e.g. (Arg)9) with cell-penetrating properties are neuroprotective. (Arg)9 provides significant neuroprotection in a dose–response manner following glutamic acid exposure with IC50 of 0.78 μM. Following kainic acid exposure, (Arg)9 is neuroprotective, but less effective than in the glutamic acid model with IC50 of 0.81 μM. (Arg)9 also shows neuroprotection following in vitro ischemia with IC50 of 6 μM[1]. |
| In vivo | In rat stroke models, (Arg)9) (D-isoform) is neuroprotective. (Arg)9) is highly neuroprotective, with efficacy increasing with increasing arginine content, has the capacity to reduce glutamic acid-induced neuronal calcium influx and requires heparan sulfate preotoglycan-mediated endocytosis to induce a neuroprotective effect[2]. (Arg) 9) (D-isoform) was administered intravenously at a dose of 1000 nmol/kg 30 minutes after permanent middle cerebral artery occlusion (MCAO) [3]. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | neuroprotection | (Arg)9 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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