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Methyl 2,6-dichloroisonicotinate

Methyl 2,6-dichloroisonicotinate structure

CAS No.: 42521-09-5

Chemical Name:: Methyl 2,6-dichloroisonicotinate

Synonyms: Methyl 2,6-dichloroi;6-dichloropyridine-4-carboxylate;Methyl 2,6-dichloroisonicotinate;Methyl 2,6-dichloroisonicotinoate;methyl 2,6-dichloropyridine-4-carboxylate;Methyl 2,6-dichloro-4-pyridinecarboxylate;2,6-Dichloro-isonicotinic acid methyl ester;Methyl 2,6-dichloro-isopyridin-3-carboxylate;Methyl 2,6-dichloropyridine-4-carboxylate 97%;METHYL 2,6-DICHLORO-4-PYRIDINE-CARBOXYLIC ACID

CBNumber:: CB5708903

Molecular Formula:: C7H5Cl2NO2

Molecular Weight:: 206.03

MDL Number:: MFCD00044409

MOL File:: 42521-09-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:53:40

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Methyl 2,6-dichloroisonicotinate Properties

Melting point	82 °C
Boiling point	298℃
Density	1.426
Flash point	134℃
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Sparingly Soluble (0.13 g/L) (25°C)
pka	-4.32±0.10(Predicted)
form	powder
color	White
InChI	InChI=1S/C7H5Cl2NO2/c1-12-7(11)4-2-5(8)10-6(9)3-4/h2-3H,1H3
InChIKey	XSKGHSUHOYEBTK-UHFFFAOYSA-N
SMILES	C1(Cl)=NC(Cl)=CC(C(OC)=O)=C1
CAS DataBase Reference	42521-09-5(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

WGK Germany

HazardClass

IRRITANT

HS Code

2933399990

Storage Class

11 - Combustible Solids

NFPA 704

	1
2		0

Methyl 2,6-dichloroisonicotinate price More Price(56)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	675962	Methyl 2,6-dichloropyridine-4-carboxylate 97%	42521-09-5	5g	$407	2023-06-20	Buy
Biosynth	FM144316	Methyl 2,6-dichloroisonicotinate	42521-09-5	5g	$900	2026-06-04	Buy
Biosynth	FM144316	Methyl 2,6-dichloroisonicotinate	42521-09-5	2g	$900	2026-06-04	Buy
Biosynth	FM144316	Methyl 2,6-dichloroisonicotinate	42521-09-5	25g	$900	2026-06-04	Buy
Biosynth	FM144316	Methyl 2,6-dichloroisonicotinate	42521-09-5	1g	$900	2026-06-04	Buy

Product number	Packaging	Price	Buy
675962	5g	$407	Buy
FM144316	5g	$900	Buy
FM144316	2g	$900	Buy
FM144316	25g	$900	Buy
FM144316	1g	$900	Buy

Methyl 2,6-dichloroisonicotinate Chemical Properties, Uses, Production

Uses

It is used as pharmaceutical intermediates.

Synthesis

5398-44-7

42521-09-5

Step I. Preparation of methyl 2,6-dichloroisonicotinate A mixed solution of 187 g (0.974 mol) of 2,6-dichloroisonicotinic acid, 1650 ml of methanol and 5 ml of concentrated sulfuric acid was heated and refluxed for 24 hours. After completion of the reaction, most of the solvent was evaporated under reduced pressure to give the crude product. The crude product was dissolved in 750 ml of dichloromethane and washed sequentially with water and 1N sodium hydroxide solution. The organic layer was separated and dried with anhydrous sodium sulfate, followed by evaporation of the solvent under reduced pressure to give 174 g (86.7% yield) of methyl 2,6-dichloroisonicotinate with a melting point of 205 °C.

References

[1] Patent: US4474602, 1984, A

Methyl 2,6-dichloroisonicotinate Preparation Products And Raw materials

Raw materials

2,6-Dichloroisonicotinic acid Methanol Sulfuric acid Dichloromethane

Preparation Products

2-Methoxy-4-pyridinecarboxylic acid 2,6-Dichloro-3-nitro-4-aminopyridine 3,5-Bis(methylsulfonyl)aniline N-tert-butyl-2,6-dichloroisonicotinamide 4-AMino-6-chloro-3-nitro-2-pyridinecarbonitrile

ethyl 2,6-dimethoxyisonicotinate

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Methyl 2,6-dichloroisonicotinate Suppliers

Global Suppliers ( 180)

Supplier	Tel	Email	Country	ProdList	Advantage
Tianjin Hexin Chengsai Science and Technology Development Co., Ltd.	022-23410962 13752273685	suna@hisyntech.com	China	299	58
Shanghai Boyle Chemical Co., Ltd.	021-50182298 021-50180596	sales@boylechem.com	China	2202	55
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64

Supplier	Advantage
Tianjin Hexin Chengsai Science and Technology Development Co., Ltd.	58
Shanghai Boyle Chemical Co., Ltd.	55
J & K SCIENTIFIC LTD.	76
Alfa Aesar	84
Energy Chemical	61
Wuhan Chemwish Technology Co., Ltd	56
Capot Chemical Co., Ltd	66
Beijing Ouhe Technology Co., Ltd	60
Accela ChemBio Co.,Ltd.	64
Nanjing Chemlin Chemical Co., Ltd	64

View Latest Price from Methyl 2,6-dichloroisonicotinate manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-08-20	METHYL 2,6-DICHLOROISONICOTINATE 42521-09-5	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
	2019-09-02	METHYL 2,6-DICHLOROISONICOTINATE 42521-09-5	$1.00	1KG	≥98%	200kg	Career Henan Chemical Co

METHYL 2,6-DICHLOROISONICOTINATE
42521-09-5
$1.10
99.00%
Dideu Industries Group Limited

METHYL 2,6-DICHLOROISONICOTINATE
42521-09-5
$1.00
≥98%
Career Henan Chemical Co

Methyl 2,6-dichloroisonicotinate Spectrum

METHYL 2,6-DICHLOROISONICOTINATE(42521-09-5)MS METHYL 2,6-DICHLOROISONICOTINATE(42521-09-5)¹HNMR METHYL 2,6-DICHLOROISONICOTINATE(42521-09-5)¹³CNMR METHYL 2,6-DICHLOROISONICOTINATE(42521-09-5)IR1 METHYL 2,6-DICHLOROISONICOTINATE(42521-09-5)IR2

42521-09-5 (Methyl 2,6-dichloroisonicotinate) Related Search:

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METHYL 2,6-DICHLORO-4-PYRIDINE-CARBOXYLIC ACID 2,6-CHLORO-4-PYRIDINECARBOXYLIC ACID METHYL ESTER 4-PYRIDINECARBOXYLIC ACID, 2,6-DICHLORO-, METHYL ESTER 2,6-Dichloro-isonicotinic acid methyl ester 2,6-Dichloro-4-pyridinecarboxylic acid methyl ester 2,6-Dichloropyridine-4-carboxylic acid methyl ester Methyl 2,6-dichloro-4-pyridinecarboxylate 6-dichloropyridine-4-carboxylate methyl 2,6-dichloropyridine-4-carboxylate Methyl 2,6-dichloropyridine-4-carboxylate, 2,6-Dichloro-4-(methoxycarbonyl)pyridine Methyl 2,6-dichloropyridine-4-carboxylate 97% Methyl 2,6-dichloroisonicotinoate METHYL 2,6-DICHLOROISONICOTINATE ISO 9001：2015 REACH Methyl 2,6-dichloroi 4-Pyridinecarboxylic acid, 2,6-dichloro-, methyl ester (9CI, ACI) 2,6-dichloro-4-Pyridinecarboxylic acid methyl ester (9CI ACI) 4-Pyridinecarboxylicacid, 2,6-dichloro-, methyl est.. Methyl 2,6-dichloro-isopyridin-3-carboxylate Methyl 2,6-dichloroisonicotinate 42521-09-5 Pyridines Halogenated Heterocycles Building Blocks Heterocyclic Building Blocks Esters Pyridines