tert-Butyl 2,6-dichloroisonicotinate
- CAS No.
- 75308-46-2
- Chemical Name:
- tert-Butyl 2,6-dichloroisonicotinate
- Synonyms
- TERT-BUTYL 2,6-DICHLOROISONICOTINATE;tert-Butyl 2,6-Dichloroisonicotinate >tert-Butyl 2,6-Dichloroisonicotinate;2,6-Dichloroisonicotinic Acid t-butyl ester;tert-Butyl 2,6-Dichloropyridine-4-carboxylate;tert-Butyl 2,6-dichloro-4-pyridinecarboxylate;2,6-Dichloroisonicotinic acid tert-butyl ester;2,6-dichloro-4-pyridinecarboxylic acid tert-butyl ester;2,6-dichloro-4-pyridinecarboxylic acid 1,1-dimethylethyl ester;4-Pyridinecarboxylic acid, 2,6-dichloro-, 1,1-dimethylethyl ester
- CBNumber:
- CB4669250
- Molecular Formula:
- C10H11Cl2NO2
- Molecular Weight:
- 248.11
- MDL Number:
- MFCD08445655
- MOL File:
- 75308-46-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 80.0 to 84.0 °C |
|---|---|
| Boiling point | 326°C |
| Density | 1.278 |
| Flash point | 151°C |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | powder to crystal |
| pka | -4.43±0.10(Predicted) |
| color | White to Light yellow to Light orange |
| CAS DataBase Reference | 75308-46-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933399990 |
tert-Butyl 2,6-dichloroisonicotinate price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B3595 | tert-Butyl 2,6-Dichloroisonicotinate >98.0%(GC) | 75308-46-2 | 5g | $115 | 2026-04-30 | Buy |
| Chem-Impex | 44689 | tert-Butyl 2,6-Dichloroisonicotinate ≥98%(GC) | 75308-46-2 | 5G | $224.04 | 2026-05-19 | Buy |
| Synthonix | D38650 | tert-Butyl 2,6-dichloroisonicotinate 95+% | 75308-46-2 | 250mg | $25 | 2026-05-06 | Buy |
| Synthonix | D38650 | tert-Butyl 2,6-dichloroisonicotinate 95+% | 75308-46-2 | 1g | $30 | 2026-05-06 | Buy |
| Synthonix | D38650 | tert-Butyl 2,6-dichloroisonicotinate 95+% | 75308-46-2 | 5g | $80 | 2026-05-06 | Buy |
tert-Butyl 2,6-dichloroisonicotinate Chemical Properties, Uses, Production
Synthesis
To a solution of 2,6-dichloroisonicotinic acid (2 g, 10.4 mmol) in toluene (50 mL) N, N- dimethylformamide di-fert-butil acetal (15 mL, 62.5 mmol) was added under nitrogen atmosphere and mixture heated at 80°C overnight. Ethyl acetate was added, and the organic layer was washed with water and brine, dried (MgS04), filtered and concentrated to yield tert-Butyl 2,6-dichloroisonicotinate (2.34 g, 87 per cent) as a solid.
References
[1] Patent: WO2008/11499, 2008, A1. Location in patent: Page/Page column 37-38
[2] Organic Process Research and Development, 2009, vol. 13, # 6, p. 1145 - 1155
[3] Patent: WO2010/111058, 2010, A1. Location in patent: Page/Page column 79
tert-Butyl 2,6-dichloroisonicotinate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai civi chemical technology co.,Ltd | 86-21-34053660 | sale@labgogo.com | China | 9853 | 52 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
View Latest Price from tert-Butyl 2,6-dichloroisonicotinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-01-09 | tert-Butyl 2,6-dichloroisonicotinate
75308-46-2
|
$2.00 | 1g | 98%min | Career Henan Chemical Co |
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- tert-Butyl 2,6-dichloroisonicotinate
75308-46-2
- $2.00
- 98%min
- Career Henan Chemical Co





