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tert-Butyl 2,6-dichloroisonicotinate

CAS No.
75308-46-2
Chemical Name:
tert-Butyl 2,6-dichloroisonicotinate
Synonyms
TERT-BUTYL 2,6-DICHLOROISONICOTINATE;tert-Butyl 2,6-Dichloroisonicotinate >tert-Butyl 2,6-Dichloroisonicotinate;2,6-Dichloroisonicotinic Acid t-butyl ester;tert-Butyl 2,6-Dichloropyridine-4-carboxylate;tert-Butyl 2,6-dichloro-4-pyridinecarboxylate;2,6-Dichloroisonicotinic acid tert-butyl ester;2,6-dichloro-4-pyridinecarboxylic acid tert-butyl ester;2,6-dichloro-4-pyridinecarboxylic acid 1,1-dimethylethyl ester;4-Pyridinecarboxylic acid, 2,6-dichloro-, 1,1-dimethylethyl ester
CBNumber:
CB4669250
Molecular Formula:
C10H11Cl2NO2
Molecular Weight:
248.11
MDL Number:
MFCD08445655
MOL File:
75308-46-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 06:05:33

tert-Butyl 2,6-dichloroisonicotinate Properties

Melting point 80.0 to 84.0 °C
Boiling point 326°C
Density 1.278
Flash point 151°C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form powder to crystal
pka -4.43±0.10(Predicted)
color White to Light yellow to Light orange
CAS DataBase Reference 75308-46-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933399990

tert-Butyl 2,6-dichloroisonicotinate price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B3595 tert-Butyl 2,6-Dichloroisonicotinate >98.0%(GC) 75308-46-2 5g $115 2026-04-30 Buy
Chem-Impex 44689 tert-Butyl 2,6-Dichloroisonicotinate ≥98%(GC) 75308-46-2 5G $224.04 2026-05-19 Buy
Synthonix D38650 tert-Butyl 2,6-dichloroisonicotinate 95+% 75308-46-2 250mg $25 2026-05-06 Buy
Synthonix D38650 tert-Butyl 2,6-dichloroisonicotinate 95+% 75308-46-2 1g $30 2026-05-06 Buy
Synthonix D38650 tert-Butyl 2,6-dichloroisonicotinate 95+% 75308-46-2 5g $80 2026-05-06 Buy
Product number Packaging Price Buy
B3595 5g $115 Buy
44689 5G $224.04 Buy
D38650 250mg $25 Buy
D38650 1g $30 Buy
D38650 5g $80 Buy

tert-Butyl 2,6-dichloroisonicotinate Chemical Properties, Uses, Production

Synthesis

To a solution of 2,6-dichloroisonicotinic acid (2 g, 10.4 mmol) in toluene (50 mL) N, N- dimethylformamide di-fert-butil acetal (15 mL, 62.5 mmol) was added under nitrogen atmosphere and mixture heated at 80°C overnight. Ethyl acetate was added, and the organic layer was washed with water and brine, dried (MgS04), filtered and concentrated to yield tert-Butyl 2,6-dichloroisonicotinate (2.34 g, 87 per cent) as a solid.

References

[1] Patent: WO2008/11499, 2008, A1. Location in patent: Page/Page column 37-38
[2] Organic Process Research and Development, 2009, vol. 13, # 6, p. 1145 - 1155
[3] Patent: WO2010/111058, 2010, A1. Location in patent: Page/Page column 79

tert-Butyl 2,6-dichloroisonicotinate Preparation Products And Raw materials

Global Suppliers ( 111)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Ark Pharm, Inc. 847-367-3680 sales@arkpharminc.com United States 1669 56
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai civi chemical technology co.,Ltd 86-21-34053660 sale@labgogo.com China 9853 52
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80
TCI Europe 320-37350700 sales@tcieurope.eu Europe 23654 75

View Latest Price from tert-Butyl 2,6-dichloroisonicotinate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
tert-Butyl 2,6-dichloroisonicotinate pictures 2020-01-09 tert-Butyl 2,6-dichloroisonicotinate
75308-46-2
$2.00 1g 98%min Career Henan Chemical Co

tert-Butyl 2,6-dichloroisonicotinate Spectrum

tert-Butyl 2,6-dichloro-4-pyridinecarboxylate TERT-BUTYL 2,6-DICHLOROISONICOTINATE 2,6-dichloro-4-pyridinecarboxylic acid 1,1-dimethylethyl ester 2,6-Dichloroisonicotinic acid tert-butyl ester 2,6-Dichloroisonicotinic Acid t-butyl ester tert-Butyl 2,6-Dichloroisonicotinate tert-Butyl 2,6-Dichloropyridine-4-carboxylate 2,6-Dichloroisonicotinic Acid tert-Butyl Ester tert-Butyl 2,6-Dichloro-4-pyridinecarboxylate 2,6-Dichloro-4-pyridinecarboxylic Acid tert-Butyl Ester 2,6-dichloro-4-pyridinecarboxylic acid tert-butyl ester tert-Butyl 2,6-Dichloroisonicotinate > 4-Pyridinecarboxylic acid, 2,6-dichloro-, 1,1-dimethylethyl ester 75308-46-2