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6-(Z-amino)-1-hexanol

6-(Z-amino)-1-hexanol structure

CAS No.: 17996-12-2

Chemical Name:: 6-(Z-amino)-1-hexanol

Synonyms: Benzyl (6-hydroxyhexyl)carbamate;Z-ACP(6)-OL;Z-NH-(CH2)6-OH;Carbamic acid, (6-hy;6-(2-Amino)-1-hexanol;6-(Z-amino)-1-hexanol;CBZ-6-AMINO-HEXAN-1-OL;Benzyl (6-hydroxyhexyl);6-(Cbz-amino)-1-hexanol;N-CBZ-6-AMINO-HEXAN-1-OL

CBNumber:: CB5752618

Molecular Formula:: C14H21NO3

Molecular Weight:: 251.32

MDL Number:: MFCD00859036

MOL File:: 17996-12-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:53:40

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6-(Z-amino)-1-hexanol Properties

Melting point	80-82 °C
Boiling point	419.6±38.0 °C(Predicted)
Density	1.087±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	12.71±0.46(Predicted)
form	powder
Appearance	White to off-white Solid
BRN	2121987
InChI	InChI=1S/C14H21NO3/c16-11-7-2-1-6-10-15-14(17)18-12-13-8-4-3-5-9-13/h3-5,8-9,16H,1-2,6-7,10-12H2,(H,15,17)
InChIKey	JMOQYRXPJQMWRQ-UHFFFAOYSA-N
SMILES	C(OCC1=CC=CC=C1)(=O)NCCCCCCO
UNSPSC Code	12352200
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
PPE	Eyeshields, Gloves, type N95 (US)
Safety Statements	22-24/25
WGK Germany	3
Storage Class	11 - Combustible Solids

6-(Z-amino)-1-hexanol price More Price(56)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	95895	6-(Z-Amino)-1-hexanol ≥98.0%	17996-12-2	1g	$130	2023-06-20	Buy
TCI Chemical	B6075	6-(N-Benzyloxycarbonylamino)-1-hexanol	17996-12-2	1G	$57	2026-04-30	Buy
TCI Chemical	B6075	6-(N-Benzyloxycarbonylamino)-1-hexanol	17996-12-2	5G	$181	2026-04-30	Buy
AstaTech	57166	N-CBZ-6-AMINO-HEXAN-1-OL 97%	17996-12-2	1G	$10	2026-04-30	Buy
AstaTech	57166	N-CBZ-6-AMINO-HEXAN-1-OL 97%	17996-12-2	5G	$13	2026-04-30	Buy

Product number	Packaging	Price	Buy
95895	1g	$130	Buy
B6075	1G	$57	Buy
B6075	5G	$181	Buy
57166	1G	$10	Buy
57166	5G	$13	Buy

6-(Z-amino)-1-hexanol Chemical Properties, Uses, Production

reaction suitability

reagent type: cross-linking reagent

Synthesis

4048-33-3

501-53-1

17996-12-2

General procedure: 6-amino-1-hexanol (5.0 g, 42.7 mmol) was dissolved in a solvent mixture of tetrahydrofuran (50 mL) and water (15 mL), and benzyl chloroformate (7.3 mL, 51.2 mmol) was added slowly and dropwise at 0°C. The pH of the reaction solution was adjusted to 8-9 by adding 1N sodium hydroxide solution (12 mL). Under the condition of maintaining the temperature of the reaction system at 0 °C, 1N sodium hydroxide solution (12 mL) was slowly added to adjust the pH of the reaction solution to 8-9, a process that took about 30 min. Subsequently, the reaction mixture was continued to be stirred at room temperature for 30 minutes. Upon completion of the reaction, the reaction was extracted with ether (30 mL x 3), the organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The resulting crude product was recrystallized by solvent recrystallization of a mixture of dichloromethane and hexane to afford N-Cbz-6-amino-1-hexanol as a white crystalline solid (3.85 g, 90% yield). The structure of the product was confirmed by 1H NMR and 13C NMR: 1H NMR (400 MHz, CDCl3): δ7.34 (m, 5H, Ar-H), 5.07 (s, 2H, PhCH2), 4.73 (br, 1H, NH), 3.61 (t, J=6.4Hz, 2H, CH2O), 3.16 (dt, J=6.8,6.8 Hz, 2H, NCH2), 1.61-1.32 (m, 8H, CH2); 13C NMR (100 MHz, CDCl3): δ 156.4 (C=O), 136.6,128.5,128.1 (Ar-C), 66.6 (PhCH2), 62.7 (CH2OH), 40.9 (NHCH2), 32.5 ( CH2CH2OH), 29.9 (NHCH2CH2), 26.3 (CH2CH2CH2OH), 25.3 (NCH2CH2CH2).

References

[1] Organic and Biomolecular Chemistry, 2016, vol. 14, # 41, p. 9716 - 9719
[2] Canadian Journal of Chemistry, 1988, vol. 66, p. 1651 - 1655
[3] Chemistry - An Asian Journal, 2011, vol. 6, # 7, p. 1800 - 1810
[4] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 4, p. 912 - 921
[5] Organic and Biomolecular Chemistry, 2018, vol. 16, # 8, p. 1343 - 1350

6-(Z-amino)-1-hexanol synthesis

Synthesis of 6-(Z-amino)-1-hexanol from N-(Benzyloxycarbonyloxy)succinimide and 6-Amino-1-hexanol

6-(Z-amino)-1-hexanol Preparation Products And Raw materials

Raw materials

methyl 6-(benzyloxycarbonylamino)hexanoate Phenyl chloroformate Sodium hydroxide Water Tetrahydrofuran

N-(Benzyloxycarbonyloxy)succinimide 6-Amino-1-hexanol Benzyl chloroformate

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Preparation Products

6-(Z-amino)-1-hexanol Suppliers

Global Suppliers ( 95)

Supplier	Tel	Email	Country	ProdList	Advantage
Sangel Pharmaceutical & Chemical Factory	0571-0571-85773987 13505717485	1610413282@qq.com	China	70	58
Jinan Samuel Pharmaceutical Co., Ltd.	0531-88821801 15192360884	605818151@qq.com	China	479	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
shanghai science Bio-Pharmceutical.co,ltd.	021-021-57872719 13761402923	245662540@qq.com	China	299	60
Shanghai Topbiochem Technology Co., Ltd	021-58170097	info@topbiochem.com	China	9509	58
TOKYO CHEMICAL INDUSTRY CO., LTD.	03-36680489	Sales-JP@TCIchemicals.com	Japan	28364	80
TCI Europe	320-37350700	sales@tcieurope.eu	Europe	23654	75
TCI AMERICA	800-4238616	sales@tciamerica.com	Americas	23636	75
Wulechem Co., Ltd.	13761914825	wulesian@wulechem.com	China	285	58

Supplier	Advantage
Sangel Pharmaceutical & Chemical Factory	58
Jinan Samuel Pharmaceutical Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Energy Chemical	61
shanghai science Bio-Pharmceutical.co,ltd.	60
Shanghai Topbiochem Technology Co., Ltd	58
TOKYO CHEMICAL INDUSTRY CO., LTD.	80
TCI Europe	75
TCI AMERICA	75
Wulechem Co., Ltd.	58

View Latest Price from 6-(Z-amino)-1-hexanol manufacturers

Update time	Product	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-18	Benzyl (6-Hydroxyhexyl)carbamate 17996-12-2	1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-06-30	6-(Z-AMINO)-1-HEXANOL 17996-12-2	1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-06-27	6-(Z-AMINO)-1-HEXANOL 17996-12-2	1KG	99%	500000kg	Hebei Chuanghai Biotechnology Co., Ltd

Benzyl (6-Hydroxyhexyl)carbamate
17996-12-2
$0.00
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

6-(Z-AMINO)-1-HEXANOL
17996-12-2
98.0%
Shaanxi Dideu New Materials Co. Ltd

6-(Z-AMINO)-1-HEXANOL
17996-12-2
99%
Hebei Chuanghai Biotechnology Co., Ltd

6-(Z-amino)-1-hexanol Spectrum

6-(Z-AMINO)-1-HEXANOL(17996-12-2)¹HNMR

17996-12-2 (6-(Z-amino)-1-hexanol) Related Search:

6-Amino-1-hexanol N-Benzyloxycarbonyl-6-aminohexanoic acid N,N'-Dibenzyloxycarbonyl-D-lysine N-Boc-N'-(2-chlorobenzyloxycarbonyl)-L-lysine N-Boc-N'-Cbz-L-lysine

Z-Lys(Z)-OH H-Lys(Z)-OMe HCl N6-Cbz-L-Lysine H-Lys(Z)-OBzl HCl H-D-Lys(Z)-OBzl HCl

Boc-Lys(Z)-ONp Boc-D-Lys(Z)-OH Z-Lys(Z)-OSu Z-D-Val-Lys(Z)-OH H-D-Lys(Z)-OH

Boc-Lys(Z)-OSu Z-Lys(Z)-ONp H-Lys(Z)-OtBu.HCl

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CBZ-6-AMINO-HEXAN-1-OL BENZYL N-(6-HYDROXYHEXYL)CARBAMATE Z-NH-(CH2)6-OH Z-ACP(6)-OL N-CARBOBENZOXY-6-AMINO-1-HEXANOL N-CARBOBENZOXY-DELTA-AMINOHEXYL ALCOHOL Carbamic acid, (6-hydroxyhexyl)-, phenylmethyl ester N-CBZ-6-AMINO-HEXAN-1-OL 6-(2-Amino)-1-hexanol Carbamic acid, (6-hy N-Cbz-6-hydroxyhexylamine Benzyl (6-hydroxyhexyl) Carbamic acid, N-(6-hydroxyhexyl)-, phenylmethyl ester 6-(N-Benzyloxycarbonylamino)-1-hexanol 6-(Carbobenzoxyamino)-1-hexanol 6-(Cbz-amino)-1-hexanol N-benzyloxycarbonyl-6-amino-1-hexanol Benzyl (6-hydroxyhexyl)carbamate 6-(Z-amino)-1-hexanol 17996-12-2 C6H5CH2O2CNHCH25OH Oxygen Compounds Organic Building Blocks Building Blocks Amino Alcohols Other