4-Iodo-1-methyl-1H-imidazole
- CAS No.
- 71759-87-0
- Chemical Name:
- 4-Iodo-1-methyl-1H-imidazole
- Synonyms
- 4-IODO-1-METHYLIMIDAZOLE;EOS-60756;1-Methyl-4-iodoimidazole;4-Iodine-1-methylimidazole;4(5)-IODO-1-METHYLIMIDAZOLE;4-Iodo-1-Methyl-1H-iMidaz...;4-IODO-1-METHYL-1H-IMIDAZOLE;1H-IMIDAZOLE, 4-IODO-1-METHYL-;4-Iodo-1-methyl-1H-imidazole 98%min
- CBNumber:
- CB5754223
- Molecular Formula:
- C4H5IN2
- Molecular Weight:
- 208
- MDL Number:
- MFCD01632214
- MOL File:
- 71759-87-0.mol
- MSDS File:
- SDS
| Melting point | 51-54°C |
|---|---|
| Boiling point | 299.0±13.0 °C(Predicted) |
| Density | 2.07±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| solubility | Dichlomethane (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 4.46±0.61(Predicted) |
| color | Pale Beige |
| InChI | InChI=1S/C4H5IN2/c1-7-2-4(5)6-3-7/h2-3H,1H3 |
| InChIKey | HUQSHNLGOKQVHA-UHFFFAOYSA-N |
| SMILES | C1N(C)C=C(I)N=1 |
| CAS DataBase Reference | 71759-87-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P271-P261-P280 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| Hazard Note | Irritant |
| HS Code | 2933299090 |
4-Iodo-1-methyl-1H-imidazole price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-I708450-250MG | 4-Iodo-1-methylimidazole | 71759-87-0 | 250mg | $91 | 2026-06-03 | Buy |
| TRC | TRC-I708450-2.5G | 4-Iodo-1-methylimidazole | 71759-87-0 | 2.5g | $205 | 2026-06-03 | Buy |
| TRC | TRC-I708450-1G | 4-Iodo-1-methylimidazole | 71759-87-0 | 1g | $186 | 2026-06-03 | Buy |
| Biosynth | FI140075 | 4-Iodo-1-methyl-1H-imidazole | 71759-87-0 | 50g | $900 | 2026-06-04 | Buy |
| Biosynth | FI140075 | 4-Iodo-1-methyl-1H-imidazole | 71759-87-0 | 100g | $1925 | 2026-06-04 | Buy |
4-Iodo-1-methyl-1H-imidazole Chemical Properties, Uses, Production
Uses
4-Iodo-1-methylimidazole is a chemical reagent used in the synthesis of PET (positron emission tomography) tracers for imaging brain enzymes.
Synthesis
37067-96-2
71759-87-0
General procedure for the synthesis of 4-iodo-1-methyl-1H-imidazole from 4,5-diiodo-1-methyl-1H-imidazole: At room temperature, EtMgBr (3.0 M ether solution, 11.00 mL, 32.9 mmol) was slowly added dropwise to 4,5-diiodo-1-methyl-1H-imidazole (10.00 g, 29.9 mmol) in anhydrous CH2Cl2 ( 150 mL) solution for more than 15 minutes dropwise. The reaction mixture was then stirred for 20 minutes. After confirming complete consumption of the feedstock by TLC monitoring, the reaction was quenched by adding water (20 mL) to the reaction mixture. The organic and aqueous layers were separated and the aqueous layer was extracted with CH2Cl2 (3 x 50 mL). All organic layers were combined, dried with anhydrous Na2SO4 and concentrated under reduced pressure to afford 4-iodo-1-methylimidazole (15) as a light brown oil (5.86 g, 94% yield).
References
[1] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 5, p. 1608 - 1621
[2] Journal of Organometallic Chemistry, 2012, vol. 697, # 1, p. 33 - 40
[3] Heterocycles, 2003, vol. 60, # 1, p. 1 - 7
[4] Polish Journal of Chemistry, 1981, vol. 55, # 7/8, p. 1659 - 1665
[5] Journal of Organic Chemistry, 2007, vol. 72, # 10, p. 3741 - 3749
4-Iodo-1-methyl-1H-imidazole Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing xiangrui technology co. LTD | 021-021-00000000 15715199582 | njrich168@163.com | China | 502 | 58 |
| Gill polypeptide biopharmaceutical (dalian) co., LTD | 021-61263455 13167021076 | amy@glschina.com | China | 9699 | 58 |
| Xuchang Fengfei New Materials Technology Co., Ltd | 19713077352; 19713077352 | 1038096457@qq.com | China | 2330 | 58 |
| Chongqing Xingcan Pharmaceutical Technology Co., Ltd. | 13594048950 19923294409 | xingcanyaoye@sina.com | China | 1591 | 58 |
| Shanghai Fengluan Biotechnology Co., LTD | 13357659136 | jing.z@fengluanbiotech.com | China | 497 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
View Latest Price from 4-Iodo-1-methyl-1H-imidazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-13 | 4-Iodo-1-methyl-1H-imidazole
71759-87-0
|
1KG | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | ||
 |
2026-06-30 | 4-Iodo-1-methyl-1H-imidazole
71759-87-0
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2019-07-06 | 4-Iodo-1-methyl-1H-imidazole
71759-87-0
|
$1.00 | 1kg | 99% | 200kg | Career Henan Chemical Co |
-
- 4-Iodo-1-methyl-1H-imidazole
71759-87-0
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
-
- 4-Iodo-1-methyl-1H-imidazole
71759-87-0
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 4-Iodo-1-methyl-1H-imidazole
71759-87-0
- $1.00
- 99%
- Career Henan Chemical Co
