2,4-DICHLORO-3-NITRO-QUINOLINE
- CAS No.
- 132521-66-5
- Chemical Name:
- 2,4-DICHLORO-3-NITRO-QUINOLINE
- Synonyms
- Zinc02551827;AURORA KA-4144;2,4-Dichlor-3-nitro-chinolin;3-NITRO-2,4-DICHLORO QUINOLINE;2,4-DICHLORO-3-NITRO-QUINOLINE;Quinoline, 2,4-dichloro-3-nitro-;2,4-Dichloro-3-nitroquinoline 95%;Benzaldehyde,4-methoxy-4-(phenylmethoxy)-;2,4-DICHLORO-3-NITRO-QUINOLINE ISO 9001：2015 REACH
- CBNumber:
- CB5773772
- Molecular Formula:
- C9H4Cl2N2O2
- Molecular Weight:
- 243.05
- MDL Number:
- MFCD05666285
- MOL File:
- 132521-66-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2,4-Dichloro-3-nitroquinoline | D439308 | 50mg | $125 |
| 2,4-Dichloro-3-nitroquinoline | 4H54-5-2U | 250mg | $376 |
| 2,4-Dichloro-3-nitroquinoline | 4H54-5-2U | 1g | $824 |
| 2,4-DICHLORO-3-NITRO-QUINOLINE 97.00% | HCH0142593 | 1G | $1022.18 |
| 2,4-Dichloro-3-nitroquinoline 97% | 128520 | 1g | $495 |
| More product size | |||
| Melting point | 102 °C(Solv: methanol (67-56-1); ethyl acetate (141-78-6)) |
|---|---|
| Boiling point | 359.7±37.0 °C(Predicted) |
| Density | 1.593±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | -4.98±0.50(Predicted) |
| color | White to Off-White |
| InChI | InChI=1S/C9H4Cl2N2O2/c10-7-5-3-1-2-4-6(5)12-9(11)8(7)13(14)15/h1-4H |
| InChIKey | RSFJVCHKGRUCIC-UHFFFAOYSA-N |
| SMILES | N1C2C(=CC=CC=2)C(Cl)=C([N+]([O-])=O)C=1Cl |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933499090 |
2,4-DICHLORO-3-NITRO-QUINOLINE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | D439308 | 2,4-Dichloro-3-nitroquinoline | 132521-66-5 | 50mg | $125 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H54-5-2U | 2,4-Dichloro-3-nitroquinoline | 132521-66-5 | 250mg | $376 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H54-5-2U | 2,4-Dichloro-3-nitroquinoline | 132521-66-5 | 1g | $824 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0142593 | 2,4-DICHLORO-3-NITRO-QUINOLINE 97.00% | 132521-66-5 | 1G | $1022.18 | 2021-12-16 | Buy |
| Matrix Scientific | 128520 | 2,4-Dichloro-3-nitroquinoline 97% | 132521-66-5 | 1g | $495 | 2021-12-16 | Buy |
2,4-DICHLORO-3-NITRO-QUINOLINE Chemical Properties,Uses,Production
Uses
2,4-Dichloro-3-nitroquinoline has antitumor activity.
Uses
2,4-Dichloro-3-nitroquinoline has antitumor activity.
Synthesis
15151-57-2
132521-66-5
(2) Synthesis of 2,4-dichloro-3-nitroquinoline: In a 20 mL round-bottomed flask, 3-nitroquinoline-2,4-diol (1 g, 4.85 mmol), phosphorus trichloride (appropriate amount) and N,N-dimethylaniline (0.19 mL) were added sequentially. The reaction mixture was stirred at 90 °C for 2 hours. Upon completion of the reaction, the reaction solution was cooled to room temperature, slowly poured into ice water, and stirring was continued for 0.5 hours. The precipitate precipitated was collected by filtration and dried under vacuum overnight. The crude product was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate=5:1, v/v) to give 0.7 g of white solid product in 59.4% yield.
References
[1] Medicinal Chemistry Research, 2014, vol. 23, # 6, p. 2964 - 2975
[2] Journal of Medicinal Chemistry, 2010, vol. 53, # 11, p. 4450 - 4465
[3] Patent: WO2013/67597, 2013, A1. Location in patent: Page/Page column 78
[4] Patent: WO2018/191746, 2018, A1. Location in patent: Paragraph 0391
[5] ACS Medicinal Chemistry Letters, 2014, vol. 5, # 8, p. 921 - 926
2,4-DICHLORO-3-NITRO-QUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Zhonghan Chemical Technology Co., LTD. | +undefined15066662237 | 3281004549@qq.com | China | 291 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4017 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20284 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
View Lastest Price from 2,4-DICHLORO-3-NITRO-QUINOLINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-25 | 2,4-DICHLORO-3-NITRO-QUINOLINE
132521-66-5
|
US $0.00 / kg | 1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | |
 |
2022-03-17 | 2,4-DICHLORO-3-NITRO-QUINOLINE
132521-66-5
|
US $1.10 / g | 1g | 99.00% | 5760-20-3 | Dideu Industries Group Limited | |
 |
2019-07-06 | 2,4-DICHLORO-3-NITRO-QUINOLINE
132521-66-5
|
US $1.00 / KG | 1KG | 97% | 200KG | Career Henan Chemical Co |
-
- 2,4-DICHLORO-3-NITRO-QUINOLINE
132521-66-5
- US $0.00 / kg
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 2,4-DICHLORO-3-NITRO-QUINOLINE
132521-66-5
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 2,4-DICHLORO-3-NITRO-QUINOLINE
132521-66-5
- US $1.00 / KG
- 97%
- Career Henan Chemical Co
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