5-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE
- CAS No.
- 114744-50-2
- Chemical Name:
- 5-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE
- Synonyms
- 5-bromo-1,2,3,4-tetrahydroquinoline;Quinoline, 5-bromo-1,2,3,4-tetrahydro-;5-bromo-1,2,3,4-tetrahydroquinoline HCl;5-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE1HCL SALT;5-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE
- CBNumber:
- CB5802137
- Molecular Formula:
- C9H10BrN
- Molecular Weight:
- 212.09
- MDL Number:
- MFCD08544260
- MOL File:
- 114744-50-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-Bromo-1,2,3,4-tetrahydroquinoline | 125239 | 1.00g | $826 |
| 5-Bromo-1,2,3,4-tetrahydroquinoline 95+% | B14750 | 100mg | $35 |
| 5-Bromo-1,2,3,4-tetrahydroquinoline 95+% | B14750 | 250mg | $39 |
| 5-Bromo-1,2,3,4-tetrahydroquinoline 95+% | B14750 | 1g | $41 |
| 5-Bromo-1,2,3,4-tetrahydroquinoline 95+% | B14750 | 5g | $100 |
| More product size | |||
| Boiling point | 300℃ |
|---|---|
| Density | 1.428 |
| Flash point | 135℃ |
| storage temp. | 2-8°C(protect from light) |
| pka | 4.19±0.20(Predicted) |
| Appearance | Light yellow to brown Liquid |
| InChI | InChI=1S/C9H10BrN/c10-8-4-1-5-9-7(8)3-2-6-11-9/h1,4-5,11H,2-3,6H2 |
| InChIKey | WTZQIKXLRRDMCP-UHFFFAOYSA-N |
| SMILES | N1C2=C(C(Br)=CC=C2)CCC1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H315 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
5-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 125239 | 5-Bromo-1,2,3,4-tetrahydroquinoline | 114744-50-2 | 1.00g | $826 | 2026-05-18 | Buy |
| Synthonix | B14750 | 5-Bromo-1,2,3,4-tetrahydroquinoline 95+% | 114744-50-2 | 100mg | $35 | 2026-05-06 | Buy |
| Synthonix | B14750 | 5-Bromo-1,2,3,4-tetrahydroquinoline 95+% | 114744-50-2 | 250mg | $39 | 2026-05-06 | Buy |
| Synthonix | B14750 | 5-Bromo-1,2,3,4-tetrahydroquinoline 95+% | 114744-50-2 | 1g | $41 | 2026-05-06 | Buy |
| Synthonix | B14750 | 5-Bromo-1,2,3,4-tetrahydroquinoline 95+% | 114744-50-2 | 5g | $100 | 2026-05-06 | Buy |
5-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE Chemical Properties,Uses,Production
Synthesis
15115-60-3
114744-50-2
General procedure for the synthesis of 5-bromo-1,2,3,4-tetrahydroquinoline from 4-bromoinden-1-one: 4-bromoinden-1-one (1.05 g, 5 mmol) was dissolved in methanol (14 ml), hydroxylamine hydrochloride (1.4 g, 20 mmol) was added, and the reaction was carried out at reflux for 1 hour. After completion of the reaction, vacuum concentration was carried out followed by addition of dichloromethane and 50% sodium bicarbonate solution and stirring for 20 min. The organic layer was separated, dried with anhydrous sodium sulfate and concentrated to give a white solid in 99% yield. The white solid (5 mmol) obtained above was dissolved in dichloromethane (30 ml), cooled to 0 °C and diisobutylaluminum hydride (20 ml, 30 mmol, 1.5 M toluene solution) was added slowly. The reaction mixture was stirred at 0°C for 30 min, then moved to room temperature and continued stirring overnight. After completion of the reaction, the reaction was quenched with water under ice bath conditions, extracted with dichloromethane, the organic layer was washed with saturated brine and dried over anhydrous sodium sulfate. After concentration, it was purified by silica gel column chromatography (petroleum ether: ethyl acetate = 3:1) to give 600 mg of 5-bromo-1,2,3,4-tetrahydroquinoline as a pale yellow solid in 56.6% yield.
References
[1] Patent: CN107814785, 2018, A. Location in patent: Paragraph 0062; 0081; 0082; 0083
5-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29094 | 58 |
| Jiangsu Harvechem Ltd. | +86-0519-88784888 13912348604 | inquiry@harvechem.com | China | 311 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +8619957148339 | market18@leapchem.com | China | 24569 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +86-18168183658 | sales1@artkmedchem.com | China | 39007 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Suzhou Crst Pharmatech Co., Ltd. | 0512-62910395 17751098781 | sales@crstpharma.com | China | 497 | 58 |
View Lastest Price from 5-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-01-13 | 5-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE
114744-50-2
|
$1.00 | 1g | 99% | 10000KGS | Career Henan Chemical Co |
-
- 5-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE
114744-50-2
- $1.00
- 99%
- Career Henan Chemical Co
