β-Tocopherol
- CAS No.
- 148-03-8
- Chemical Name:
- β-Tocopherol
- Synonyms
- beta-tocopherol;5,8-DIMETHYLTOCOL;(2R)-2,5,8-trimethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol;β-Tocopherol;Neotocopherol;Cumotocopherol;Bata-Tocopherol;rac-β-Tocopherol;p-Xylotocopherol;(±)-β-Tocopherol
- CBNumber:
- CB5822456
- Molecular Formula:
- C28H48O2
- Molecular Weight:
- 416.68
- MDL Number:
- MFCD00036171
- MOL File:
- 148-03-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| rac-β-Tocopherol solution 50?mg/mL in hexane, analytical standard | 46401-U | 1mL | $298 |
| rac-β-Tocopherol solution | 46401-U | u | $223 |
| (±)-β-Tocopherol ≥95% | 26758 | 50mg | $283 |
| β-Tocopherol (Racemic Mixture) | 167293 | 5mg | $531 |
| β-Tocopherol | XT183473 | 1g | $2855.6 |
| More product size | |||
| Melting point | <25℃ |
|---|---|
| Boiling point | 474.94°C (rough estimate) |
| Density | 0.9882 (rough estimate) |
| refractive index | 1.4480 (estimate) |
| Flash point | -23 °C |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), Ethanol (Slightly), Ethyl Acetate (Slightly), Methanol ( |
| pka | 11.05±0.40(Predicted) |
| form | Oil |
| color | Colourless to Yellow |
| InChI | InChI=1/C28H48O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-24(6)26(29)19-23(5)27(25)30-28/h19-22,29H,8-18H2,1-7H3/t21-,22-,28-/s3 |
| InChIKey | WGVKWNUPNGFDFJ-UHFFFAOYSA-N |
| SMILES | [C@@]1(C)(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)OC2=C(C)C=C(O)C(C)=C2CC1 |&1:0,5,10,r| |
| LogP | 10.724 (est) |
| FDA UNII | 8K9365K9PX |
| EPA Substance Registry System | 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)-rel- (148-03-8) |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS02,GHS07,GHS08,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H225-H304-H315-H336-H361f-H373-H411 |
| Precautionary statements | P210-P260-P280-P301+P310-P370+P378-P403+P235 |
| target organs | Eyes,Central nervous system |
| Hazard Codes | F,Xn,N |
| Risk Statements | 11-38-48/20-51/53-62-67-65 |
| Safety Statements | 36/37-61-62-16 |
| RIDADR | UN1208 3/PG 2 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Acute Tox. 3 Dermal Acute Tox. 3 Inhalation Acute Tox. 3 Oral Flam. Liq. 2 STOT SE 1 |
β-Tocopherol price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 46401-U | rac-β-Tocopherol solution 50?mg/mL in hexane, analytical standard | 148-03-8 | 1mL | $298 | 2024-03-01 | Buy |
| Sigma-Aldrich | 46401-U | rac-β-Tocopherol solution | 148-03-8 | u | $223 | 2021-12-16 | Buy |
| Cayman Chemical | 26758 | (±)-β-Tocopherol ≥95% | 148-03-8 | 50mg | $283 | 2026-04-30 | Buy |
| Usbiological | 167293 | β-Tocopherol (Racemic Mixture) | 148-03-8 | 5mg | $531 | 2026-06-03 | Buy |
| Biosynth | XT183473 | β-Tocopherol | 148-03-8 | 1g | $2855.6 | 2026-06-05 | Buy |
β-Tocopherol Chemical Properties,Uses,Production
Description
(±)-β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals with an EC50 value of 68.2 μM. (±)-β-Tocopherol (100 μM) inhibits LPS-induced COX-2 gene expression in mouse RAW 264.7 macrophage cells. Unlike (±)-α-tocopherol , (±)-β-tocopherol does not inhibit smooth muscle cell proliferation, decrease PKC activity, increase phosphoprotein phosphatase 2A (PP2A) activity, or modify expression of the α-tropomyosin gene. [Matreya, LLC. Catalog No. 1071]
Uses
One of the naturally occurring forms of Vitamin E. Is biologically less active than α-Tocopherol. This is the racemic mixture of all stereoisomers.
Definition
ChEBI: Beta-tocopherol is a tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 5 and 8. While it is found in low concentrations in many vegetable oils, only cottonseed oil contains significant amounts. It has a role as a plant metabolite and a food component. It is a vitamin E and a tocopherol.
References
[1] REGINA BRIGELIUS-FLOHé Maret G T. Vitamin E: function and metabolism[J]. FASEB Journal, 1999, 13 10: 1145-1155. DOI: 10.1096/fasebj.13.10.1145
[2] CHIY-RONG CHEN. Tocopherols and Triterpenoids from Sida acuta[C]//54 1. 2013: 41-45. DOI: 10.1002/jccs.200700008
[3] YUKIO MURAKAMI. Inhibitory effects of tocopherols on expression of the cyclooxygenase-2 gene in RAW264.7 cells stimulated by lipopolysaccharide, tumor necrosis factor-α or Porphyromonas gingivalis fimbriae.[J]. In vivo, 2013, 27 4: 451-458.
β-Tocopherol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +86-18080483897 | sales@biopurify.com | China | 4616 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9984 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49709 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501 | product@acmec-e.com | China | 33301 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | info@chemextension.com | China | 42052 | 58 |
View Lastest Price from β-Tocopherol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Beta-Tocopherol
148-03-8
|
$40.00-89.00 | 99.88% | 10g | TargetMol Chemicals Inc. |
-
- Beta-Tocopherol
148-03-8
- $40.00-89.00
- 99.88%
- TargetMol Chemicals Inc.
