4,4'-Difluorobenzil
- CAS No.
- 579-39-5
- Chemical Name:
- 4,4'-Difluorobenzil
- Synonyms
- 4,4'-FLUOROBENZIL;p,p'-Difluorobenzil;4,4'-Difluorobenzil;4,4'- difluorobenzoyl;4,4'-Difluorobenzil>4,4'-DIFLUOROBIBENZOYL;4,4'-Difluorodibenzoyl;4,4'-Difluorobenzil,99%;4,4'-Difluorobenzil, 98+%;BIS(P-FLUOROPHENYL)ETHANEDIONE
- CBNumber:
- CB6112871
- Molecular Formula:
- C14H8F2O2
- Molecular Weight:
- 246.21
- MDL Number:
- MFCD00134541
- MOL File:
- 579-39-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 120-122 °C (lit.) |
|---|---|
| Boiling point | 370.2±27.0 °C(Predicted) |
| Density | 1.3163 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| color | Light orange to Yellow to Green |
| Water Solubility | Soluble in water. |
| BRN | 1971736 |
| InChI | InChI=1S/C14H8F2O2/c15-11-5-1-9(2-6-11)13(17)14(18)10-3-7-12(16)8-4-10/h1-8H |
| InChIKey | BRKULQOUSCHDGS-UHFFFAOYSA-N |
| SMILES | C(C1=CC=C(F)C=C1)(=O)C(C1=CC=C(F)C=C1)=O |
| CAS DataBase Reference | 579-39-5(CAS DataBase Reference) |
| EPA Substance Registry System | Ethanedione, bis(4-fluorophenyl)- (579-39-5) |
| UNSPSC Code | 12352100 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280a-P304+P340-P405-P501a | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29147000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
4,4'-Difluorobenzil price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D2292 | 4,4'-Difluorobenzil >98.0%(GC) | 579-39-5 | 5g | $45 | 2026-04-30 | Buy |
| Apolloscientific | PC2534 | 4,4'-Difluorobenzil 98% | 579-39-5 | 5g | $47 | 2026-06-04 | Buy |
| Apolloscientific | PC2534 | 4,4'-Difluorobenzil 98% | 579-39-5 | 25g | $170 | 2026-06-04 | Buy |
| Chem-Impex | 45634 | 4,4'-Difluorobenzil ≥98%(GC) | 579-39-5 | 5G | $91.1 | 2026-05-19 | Buy |
| Matrix Scientific | 097754 | 1,2-Bis(4-fluorophenyl)ethane-1,2-dione | 579-39-5 | 1.00g | $38 | 2026-05-18 | Buy |
4,4'-Difluorobenzil Chemical Properties, Uses, Production
Chemical Properties
pale yellow powder
Uses
4,4′-Difluorobenzil is suitable for use in the preparation of 2,3-bis(4-fluorophenyl)thieno[3,4-b]pyrazine. It may be used in the synthesis of following:
- poly(ether-α-diketone)s, via nucleophilic substitution reaction with bisphenol A
- 4,4′-difluoro-2,3-diphenylpyrazine (DPPF) and 4,4′-difluoro-5-methyl 2,3-diphenylpyrazine (MDPPF), via direct condensation with ethylenediamine and 1,2-diaminopropane, respectively
- 2,3-bis(4-fluorophenyl)quinoxaline, via direct condensation with 1,2-phenylenediamine
Synthesis Reference(s)
Tetrahedron Letters, 35, p. 2959, 1994 DOI: 10.1016/S0040-4039(00)76671-8
General Description
4,4′-Difluorobenzil is a benzil derivative. Its reaction with benzylurea and phenethylurea has been investigated. It is reported to undergo condensation with Fe2(SH)2(CO)6 to afford the adduct Fe2[S2C2(OH)2(C6H4-4-F)2](CO)6.
4,4'-Difluorobenzil Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan Shangang Biopharmaceutical Technology Co., Ltd | 13990000934,13076045191 13990000934 | 7109671@qq.com | China | 308 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 |
View Latest Price from 4,4'-Difluorobenzil manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-05-26 | 4,4'-DIFLUOROBENZIL
579-39-5
|
$120.00 | 1kg | 0.99 | 1000000 | Hebei Fengjia New Material Co., Ltd | |
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2025-04-04 | 4,4'-Difluorobenzil
579-39-5
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
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2022-01-18 | 4,4'-DIFLUOROBENZIL
579-39-5
|
1KG | 97.8% | 100 tons | Honest Joy Holdings Limited |
-

- 4,4'-DIFLUOROBENZIL
579-39-5
- $120.00
- 0.99
- Hebei Fengjia New Material Co., Ltd
-

- 4,4'-Difluorobenzil
579-39-5
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-

- 4,4'-DIFLUOROBENZIL
579-39-5
- $0.00
- 97.8%
- Honest Joy Holdings Limited







