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4-CHLORO-6-METHYLTHIOPYRIMIDINE

4-CHLORO-6-METHYLTHIOPYRIMIDINE Structure
4-CHLORO-6-METHYLTHIOPYRIMIDINE structure
CAS No.
89283-48-7
Chemical Name:
4-CHLORO-6-METHYLTHIOPYRIMIDINE
Synonyms
4-CHLORO-6-METHYLTHIOPYRIMIDINE;4-chloro-6-MethylpyriMidine-1-thiol;Pyrimidine, 4-chloro-6-(methylthio)-;4-Chloro-6-methylsulfanyl-pyrimidine;4-CHLORO-6-METHYLTHIOPYRIMIDINE ISO 9001：2015 REACH
CBNumber:
CB61215962
Molecular Formula:
C5H5ClN2S
Molecular Weight:
160.62
MDL Number:
MFCD09870036
MOL File:
89283-48-7.mol
MSDS File:
SDS
Last updated:2026-05-28 01:59:14
Product description Number Pack Size Price
4-Chloro-6-methylthiopyrimidine Aldrich SYX00015 1g $191
4-Chloro-6-methylthiopyrimidine 97% OR960614 1g $21
4-Chloro-6-methylthiopyrimidine 97% OR960614 5g $70
4-Chloro-6-methylthiopyrimidine 97% OR960614 25g $225
4-Chloro-6-methylthiopyrimidine 97% OR960614 100g $872
Request For Quotation

4-CHLORO-6-METHYLTHIOPYRIMIDINE Properties

Melting point 50-51 °C
Boiling point 260 ºC
Density 1.37
Flash point 111 ºC
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form solid
pka -1.50±0.17(Predicted)
Appearance Light yellow to yellow Solid
InChI 1S/C5H5ClN2S/c1-9-5-2-4(6)7-3-8-5/h2-3H,1H3
InChIKey BMQSAIGMUNXTKZ-UHFFFAOYSA-N
SMILES CSc1cc(Cl)ncn1
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280
Risk Statements  43
Safety Statements  36/37
WGK Germany  3
HS Code  2933599590
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Skin Sens. 1

4-CHLORO-6-METHYLTHIOPYRIMIDINE price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SYX00015 4-Chloro-6-methylthiopyrimidine Aldrich 89283-48-7 1g $191 2026-04-30 Buy
Apolloscientific OR960614 4-Chloro-6-methylthiopyrimidine 97% 89283-48-7 1g $21 2026-06-04 Buy
Apolloscientific OR960614 4-Chloro-6-methylthiopyrimidine 97% 89283-48-7 5g $70 2026-06-04 Buy
Apolloscientific OR960614 4-Chloro-6-methylthiopyrimidine 97% 89283-48-7 25g $225 2026-06-04 Buy
Apolloscientific OR960614 4-Chloro-6-methylthiopyrimidine 97% 89283-48-7 100g $872 2026-06-04 Buy
Product number Packaging Price Buy
SYX00015 1g $191 Buy
OR960614 1g $21 Buy
OR960614 5g $70 Buy
OR960614 25g $225 Buy
OR960614 100g $872 Buy

4-CHLORO-6-METHYLTHIOPYRIMIDINE Chemical Properties,Uses,Production

Synthesis

4,6-Dichloropyrimidine

1193-21-1

Sodium thiomethoxide

5188-07-8

4-CHLORO-6-METHYLTHIOPYRIMIDINE

89283-48-7

Example 12: Synthesis of 4-chloro-6-(methylthio)pyrimidine. 4,6-Dichloropyrimidine (15.4 g, 0.10 mol) was dissolved in THF (120 mL) at room temperature, followed by the addition of solid sodium methanethiol (NaSMe, 8.5 g, 0.12 mol). The reaction mixture was heated to 60 °C and maintained for 16 hours. After completion of the reaction, the mixture was cooled to room temperature and diluted with ethyl acetate (300 mL) and water (300 mL). The organic layer was separated, washed with brine, dried over anhydrous sodium sulfate and concentrated to give an orange colored oil. Recrystallization by hexane gave the light yellow solid product 4-chloro-6-(methylthio)pyrimidine (9.85 g, 0.061 mol, 61% yield).1H NMR (500 MHz, CDCl3) δ: 8.74 (s, 1H), 7.23 (s, 1H), 2.58 (s, 3H).

References

[1] Patent: WO2006/52913, 2006, A1. Location in patent: Page/Page column 236-237
[2] Patent: WO2008/77548, 2008, A1. Location in patent: Page/Page column 46
[3] Patent: WO2009/85913, 2009, A1. Location in patent: Page/Page column 64-65
[4] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 23, p. 6529 - 6533
[5] Patent: WO2011/45353, 2011, A1. Location in patent: Page/Page column 42-43

4-CHLORO-6-METHYLTHIOPYRIMIDINE Preparation Products And Raw materials

Raw materials

4,6-Dichloropyrimidine Sodium thiomethoxide

Preparation Products

4-CHLORO-6-METHYLTHIOPYRIMIDINE Suppliers

Global( 87)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED 		sales@conier.com China 49906 58
Fuxin Pharmaceutical 		+86-021-021-50872116 contact@fuxinpharm.com China 9976 58
Career Henan Chemica Co 		+86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
Win-Win chemical CO., Limited 		+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14301 58
Dideu Industries Group Limited 		+8617392712697 1022@dideu.com China 29091 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 17705817739 info@dycnchem.com China 52693 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 +86-15355479329 market18@leapchem.com China 43303 58
Aladdin Scientific 		tp@aladdinsci.com United States 54746 58
Suzhou ARTK Medchem Co., Ltd. 		+86-18168183658 sales1@artkmedchem.com China 39007 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131885 58
Supplier Advantage
CONIER CHEM AND PHARMA LIMITED 		58
Fuxin Pharmaceutical 		58
Career Henan Chemica Co 		58
Win-Win chemical CO., Limited 		58
Dideu Industries Group Limited 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Aladdin Scientific 		58
Suzhou ARTK Medchem Co., Ltd. 		58
Amadis Chemical Company Limited 		58

View Lastest Price from 4-CHLORO-6-METHYLTHIOPYRIMIDINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-CHLORO-6-METHYLTHIOPYRIMIDINE pictures 2026-08-20 4-CHLORO-6-METHYLTHIOPYRIMIDINE
89283-48-7
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited

4-CHLORO-6-METHYLTHIOPYRIMIDINE Spectrum

4-CHLORO-6-METHYLTHIOPYRIMIDINE(89283-48-7)1HNMR

89283-48-7(4-CHLORO-6-METHYLTHIOPYRIMIDINE)Related Search:

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4-CHLORO-6-METHYLTHIOPYRIMIDINE 4-chloro-6-MethylpyriMidine-1-thiol 4-Chloro-6-methylsulfanyl-pyrimidine Pyrimidine, 4-chloro-6-(methylthio)- 4-CHLORO-6-METHYLTHIOPYRIMIDINE ISO 9001：2015 REACH 89283-48-7 Heterocycle-Pyrimidine series