Marbofloxacin
- CAS No.
- 115550-35-1
- Chemical Name:
- Marbofloxacin
- Synonyms
- Marbofloxacine;9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,3,4]oxadiazino[6,5,4-ij]quinoline-6-carboxylic acid;CS-939;zeniquin;Marbocyl;ZENIQUIN(R);Ma Bo effect;Mapofloxacin;MARBOFLOXACIN;Marbifloxacin
- CBNumber:
- CB6125860
- Molecular Formula:
- C17H19FN4O4
- Molecular Weight:
- 362.36
- MDL Number:
- MFCD00864820
- MOL File:
- 115550-35-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Marbofloxacin European Pharmacopoeia (EP) Reference Standard | Y0000819 | 10 mg | $241 |
| Marbofloxacin VETRANAL?, analytical standard | 34039 | 100MG | $147 |
| Marbofloxacin European Pharmacopoeia (EP) Reference Standard | Y0000819 | y0000819 | $220 |
| Marbofloxacin >98.0%(HPLC)(T) | M2240 | 1g | $142 |
| Marbofloxacin >98.0%(HPLC)(T) | M2240 | 5g | $419 |
| More product size | |||
| Melting point | 268-269°C (dec.) |
|---|---|
| Boiling point | 571℃ |
| Density | 1.55±0.1 g/cm3(Predicted) |
| Flash point | >110°(230°F) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly, Heated) |
| form | Solid |
| pka | 6.02±0.20(Predicted) |
| color | Light Yellow |
| Water Solubility | Soluble in DMSO at 2mg/ml. Soluble in water or ethanol at <1mg/ml |
| Merck | 14,5750 |
| InChI | InChI=1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25) |
| InChIKey | BPFYOAJNDMUVBL-UHFFFAOYSA-N |
| SMILES | N12C=C(C(O)=O)C(=O)C3=C1C(=C(N1CCN(C)CC1)C(F)=C3)OCN2C |
| CAS DataBase Reference | 115550-35-1(CAS DataBase Reference) |
| FDA UNII | 8X09WU898T |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H412 | |||||||||
| Precautionary statements | P273-P501 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 52/53-36/37/38 | |||||||||
| Safety Statements | 61-36-26-60 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | UU8815140 | |||||||||
| HS Code | 29349990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Aquatic Chronic 3 | |||||||||
| NFPA 704 |
|
Marbofloxacin price More Price(88)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000819 | Marbofloxacin European Pharmacopoeia (EP) Reference Standard | 115550-35-1 | 10 mg | $241 | 2026-04-30 | Buy |
| Sigma-Aldrich | 34039 | Marbofloxacin VETRANAL?, analytical standard | 115550-35-1 | 100MG | $147 | 2026-04-30 | Buy |
| Sigma-Aldrich | Y0000819 | Marbofloxacin European Pharmacopoeia (EP) Reference Standard | 115550-35-1 | y0000819 | $220 | 2024-03-01 | Buy |
| TCI Chemical | M2240 | Marbofloxacin >98.0%(HPLC)(T) | 115550-35-1 | 1g | $142 | 2026-04-30 | Buy |
| TCI Chemical | M2240 | Marbofloxacin >98.0%(HPLC)(T) | 115550-35-1 | 5g | $419 | 2026-04-30 | Buy |
Marbofloxacin Chemical Properties,Uses,Production
Brand Name(s) in US
Zeniquin, Marbocyl
Description
Marbofloxacin is a fluoroquinolone antibiotic that is active against P. multocida in vitro (MIC = 0.016 μg/ml). It exhibits broad-spectrum antibacterial activity mediated by the inhibition of DNA gyrase, with MIC values ranging from 0.016 to 0.4 and 0.19 to 1.7 μg/ml against various Gram-negative and Gram-positive bacterial isolates, respectively. In vivo, the administration of marbofloxacin (2 mg/kg, i.m.) after infection prevents the formation of pulmonary lesions in a bovine calf model of M. haemolytica A1 pneumonia. Oral marbofloxacin (2 mg/kg per day) also exhibits antileishmanial activity in a canine model of leishmaniasis, decreasing parasitic load by 72%. Formulations containing marbofloxacin have been used in the veterinary treatment of bacterial infections.
Chemical Properties
Crystalline Solid
Uses
Fluorinated quinolone antibacterial
Uses
A broad spectrum antibiotic commonly used to target Pseudomonas and Staphylococci species
Definition
ChEBI: A fluoroquinolone antibiotic that is 7-oxo-2,3-dihydro-7H-[1,3,4]oxadiazino[6,5,4-ij]quinoline substituted at positions 6, 9 and 10 by carboxy, fluoro and 4-methylpiperazin-1-yl groups, respectively. A synthetic, broad spect um bactericidal agent, it is used in veterinary medicine, although its mechanism of action is not thoroughly understood.
Application
Marbofloxacin is an FDA-approved broad-spectrum bactericidal fluoroquinolone available in oral tablet and injectable forms. It has been shown to have varying therapeutic effects in a wide range of animal diseases in dogs, cats, horses, cattle and pigs. It can be used to treat skin and soft tissue infections in dogs and cats, urinary tract infections in dogs, some blood borne pathogens (e.g. Mycoplasma haematobium) in cats, equine infections caused by susceptible bacteria, bovine respiratory disease, and porcine respiratory disease pathogens.
Side effects
The most common side effects of Marbofloxacin are vomiting, diarrhoea and loss of appetite. More serious side effects include cartilage abnormalities (which may cause difficulty walking), prolonged loss of appetite, incoordination, convulsions, depression, fever, rash, or difficulty breathing. Blindness and eye damage in cats has been a concern at high doses.
Veterinary Drugs and Treatments
Marbofloxacin is labeled for the treatment of susceptible bacterial infections in dogs and cats.
References
[1] AUDE A. FERRAN Alain B M Pierre Louis Toutain. Impact of early versus later fluoroquinolone treatment on the clinical; microbiological and resistance outcomes in a mouse-lung model of Pasteurella multocida infection[J]. Veterinary microbiology, 2011, 148 2: Pages 292-297. DOI: 10.1016/j.vetmic.2010.09.005
[2] M. SPRENG. Antibacterial activity of marbofloxacin. A new fluoroquinolone for veterinary use against canine and feline isolates[J]. Journal of veterinary pharmacology and therapeutics, 1995, 18 4: 284-289. DOI: 10.1111/j.1365-2885.1995.tb00592.x
[3] G. LHERMIE. Impact of Timing and Dosage of a Fluoroquinolone Treatment on the Microbiological, Pathological, and Clinical Outcomes of Calves Challenged with Mannheimia haemolytica[J]. Frontiers in Microbiology, 2016, 7 1. DOI: 10.3389/fmicb.2016.00237
[4] CARMEN PINEDA. Treatment of canine leishmaniasis with marbofloxacin in dogs with renal disease.[J]. PLoS ONE, 2017: e0185981. DOI: 10.1371/journal.pone.0185981
Marbofloxacin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hpets Biotech Company (Chongqing) Co.,ltd | +86-13272734230 | info@hanpets.com | China | 26 | 58 |
| shandong perfect biotechnology co.ltd | +86-53169958659 +86-13153181156 | sales@sdperfect.com | China | 294 | 58 |
| Linyi Changqing Chemical Co., LTD | +86-0532-55729510 +86-15853232676 | marketing@echemi.com | China | 288 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-17392712779 | 1097@dideu.com | China | 3992 | 58 |
| Anhui Ruihan Technology Co., Ltd | +undefined17756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +86-17331189928 | admin@guyunchem.com | China | 615 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | sarah@tnjone.com | China | 1143 | 58 | |
| Henan Suikang Pharmaceutical Co.,Ltd. | +86-18239973690 | sales@suikangpharm.com | China | 311 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
Related articles
- Veterinary drug Marbofloxacin: Uses, Mechanism of action, Adverse reactions and Toxicity
- Marbofloxacin is a synthetic fluoroquinolone veterinary-specific antimicrobial drug with broad-spectrum antibacterial activity....
- Mar 6，2024
View Lastest Price from Marbofloxacin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-31 | Marbofloxacin
115550-35-1
|
$1.00 | 1KG | 99.0% ~ 101.0% | 50KG/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2026-07-30 | Marbofloxacin
115550-35-1
|
1KG | 99% | 500kgs | Xi an Biohorlden Industry Trade Co Ltd | ||
 |
2026-05-11 | Marbofloxacin
115550-35-1
|
$30.00-35.00 | 99.98% | 10g | TargetMol Chemicals Inc. |
-
- Marbofloxacin
115550-35-1
- $1.00
- 99.0% ~ 101.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Marbofloxacin
115550-35-1
- $0.00
- 99%
- Xi an Biohorlden Industry Trade Co Ltd
-
- Marbofloxacin
115550-35-1
- $30.00-35.00
- 99.98%
- TargetMol Chemicals Inc.
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