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ChemicalBook >> CAS DataBase List >>Benzonitrile, 3-[[3,4-dioxo-2-[[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]amino]-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)-

Benzonitrile, 3-[[3,4-dioxo-2-[[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]amino]-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)-

Benzonitrile, 3-[[3,4-dioxo-2-[[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]amino]-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)- Structure
Benzonitrile, 3-[[3,4-dioxo-2-[[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]amino]-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)- structure
CAS No.
2851820-52-3
Chemical Name:
Benzonitrile, 3-[[3,4-dioxo-2-[[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]amino]-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)-
Synonyms
HR-19011;3-((3,4-Dioxo-2-((trans-4-(4-(trifluoromethyl)phenoxy)cyclohexyl)amino)cyclobut-1-en-1-yl)amino)-5-(trifluoromethyl)benzonitrile;Benzonitrile, 3-[[3,4-dioxo-2-[[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]amino]-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)-
CBNumber:
CB613201760
Molecular Formula:
C25H19F6N3O3
Molecular Weight:
523.43
MDL Number:
MOL File:
2851820-52-3.mol
MSDS File:
SDS
Last updated:2026-05-28 02:15:21
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Benzonitrile, 3-[[3,4-dioxo-2-[[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]amino]-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)- Properties

Boiling point 561.4±60.0 °C(Predicted)
Density 1.47±0.1 g/cm3(Predicted)
pka -0.44±0.20(Predicted)
form Solid
color White to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H315-H318-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338-P310-P332+P313-P362-P403+P233-P405-P501

Benzonitrile, 3-[[3,4-dioxo-2-[[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]amino]-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0529203 HR-19011 99.64% 2851820-52-3 5mg $173 2026-06-04 Buy
ChemScene CS-0529203 HR-19011 99.64% 2851820-52-3 10mg $282 2026-06-04 Buy
ChemScene CS-0529203 HR-19011 99.64% 2851820-52-3 25mg $563 2026-06-04 Buy
ChemScene CS-0529203 HR-19011 99.64% 2851820-52-3 50mg $910 2026-06-04 Buy
ChemScene CS-0529203 HR-19011 99.64% 2851820-52-3 100mg $1462 2026-06-04 Buy
Product number Packaging Price Buy
CS-0529203 5mg $173 Buy
CS-0529203 10mg $282 Buy
CS-0529203 25mg $563 Buy
CS-0529203 50mg $910 Buy
CS-0529203 100mg $1462 Buy

Benzonitrile, 3-[[3,4-dioxo-2-[[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]amino]-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)- Chemical Properties, Uses, Production

Uses

EIF2α activator 1 (Compound 40) is an activator of eukaryotic initiation factor 2 alpha (eIF2α) phosphorylation. EIF2α activator 1 increases the expression level of eIF2α downstream proteins, ATF and CHOP. EIF2α activator 1 exhibits antiproliferative activity againist K562 and PBMC cells with IC50s of 4.00 and 19.3 μM, respectively[1].

IC 50

eIF2

References

[1] Jinsook Kwak, et al. A bioisosteric approach to the discovery of novel N-aryl-N'-[4-(aryloxy)cyclohexyl]squaramide-based activators of eukaryotic initiation factor 2 alpha (eIF2α) phosphorylation. Eur J Med Chem. 2022 May 29;239:114501. DOI:10.1016/j.ejmech.2022.114501

Benzonitrile, 3-[[3,4-dioxo-2-[[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]amino]-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzonitrile, 3-[[3,4-dioxo-2-[[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]amino]-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)- Suppliers

Global Suppliers ( 9)
Supplier Tel Email Country ProdList Advantage
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2996 55
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9792 55
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Hubei wei shi reagent group ltd., company 17771898297 13125137661 2853877621@qq.com China 7993 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. +1-781-999-5354; support@targetmol.com United States 38999 58
Aladdin Scientific tp@aladdinsci.com United States 50089 58
Supplier Advantage
Shanghai Beckham Medical Technology Co., Ltd 55
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Beijing Jin Ming Biotechnology Co., Ltd. 58
Bide Pharmatech Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Hubei wei shi reagent group ltd., company 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58
Aladdin Scientific 58

View Latest Price from Benzonitrile, 3-[[3,4-dioxo-2-[[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]amino]-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
HR-19011 pictures 2025-12-27 HR-19011
2851820-52-3
 $76.00 99.89% 10g TargetMol Chemicals Inc.
EIF2α activator 1 pictures 2025-04-30 EIF2α activator 1
2851820-52-3
 $145.00 10g TargetMol Chemicals Inc.
  • HR-19011 pictures
  • HR-19011
    2851820-52-3
  • $76.00
  • 99.89%
  • TargetMol Chemicals Inc.

2851820-52-3 (Benzonitrile, 3-[[3,4-dioxo-2-[[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]amino]-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)-) Related Search:

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Benzonitrile, 3-[[3,4-dioxo-2-[[trans-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]amino]-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)- 3-((3,4-Dioxo-2-((trans-4-(4-(trifluoromethyl)phenoxy)cyclohexyl)amino)cyclobut-1-en-1-yl)amino)-5-(trifluoromethyl)benzonitrile HR-19011 2851820-52-3