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HJ445A

HJ445A Structure
HJ445A structure
CAS No.
3032441-59-8
Chemical Name:
HJ445A
Synonyms
HJ445A;Benzamide, 3-[3-ethyl-5-(4-methoxyphenyl)-1H-1,2,4-triazol-1-yl]-N-[4-(2H-1,2,3-triazol-2-yl)butyl]-
CBNumber:
CB614260847
Molecular Formula:
C24H27N7O2
Molecular Weight:
445.52
MDL Number:
MOL File:
3032441-59-8.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:17
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HJ445A Properties

Density 1.26±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka 14.06±0.46(predicted)
form Solid
color White to off-white

HJ445A price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0910886 HJ445A 98.31% 3032441-59-8 1mg $162 2026-06-04 Buy
ChemScene CS-0910886 HJ445A 98.31% 3032441-59-8 5mg $411 2026-06-04 Buy
ChemScene CS-0910886 HJ445A 98.31% 3032441-59-8 10mg $616 2026-06-04 Buy
ChemScene CS-0910886 HJ445A 98.31% 3032441-59-8 25mg $1234 2026-06-04 Buy
ChemScene CS-0910886 HJ445A 98.31% 3032441-59-8 50mg $1851 2026-06-04 Buy
Product number Packaging Price Buy
CS-0910886 1mg $162 Buy
CS-0910886 5mg $411 Buy
CS-0910886 10mg $616 Buy
CS-0910886 25mg $1234 Buy
CS-0910886 50mg $1851 Buy

HJ445A Chemical Properties,Uses,Production

Uses

HJ445A is a potent MYOF inhibitor and binds to the MYOF-C2D domain with a KD of 0.17 μM. HJ445A potently repressed the proliferation of gastric cancer cells with IC50 values of 0.16 and 0.14 μM in MGC803 and MKN45, respectively. HJ445A demonstrates superior antitumor efficacy in vivo and can be used for cancer research[1].

References

[1] Haijun Gu, et al. Discovery of a Highly Potent and Selective MYOF Inhibitor with Improved Water Solubility for the Treatment of Gastric Cancer. J Med Chem. 2023 Dec 6. DOI:10.1021/acs.jmedchem.3c01639

HJ445A Preparation Products And Raw materials

Raw materials

Preparation Products

HJ445A Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
Guangzhou Younan Technology Co., Ltd 020-82000279 18988941452 YN_research@163.com China 2984 58
Henan Jinbak New Material Technology Co., Ltd 18737135779 1169001743@qq.com China 106 58
TargetMol 400-821-0310 15002144251 xuexiang.shao@tsbiochem.com China 29128 58
Supplier Advantage
Guangzhou Younan Technology Co., Ltd 58
Henan Jinbak New Material Technology Co., Ltd 58
TargetMol 58

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HJ445A Benzamide, 3-[3-ethyl-5-(4-methoxyphenyl)-1H-1,2,4-triazol-1-yl]-N-[4-(2H-1,2,3-triazol-2-yl)butyl]- 3032441-59-8