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pan-KRAS-IN-5

pan-KRAS-IN-5 Structure
pan-KRAS-IN-5 structure
CAS No.
3027172-23-9
Chemical Name:
pan-KRAS-IN-5
Synonyms
pan-KRAS-IN-5;Quinolinium, 2-[(1E)-2-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]ethenyl]-6-fluoro-1-methyl-7-[[2-(1-pyrrolidinyl)ethyl]amino]-, iodide (1:1)
CBNumber:
CB614284179
Molecular Formula:
C31H36FN4O2.I
Molecular Weight:
642.55
MDL Number:
MOL File:
3027172-23-9.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:18
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pan-KRAS-IN-5 Properties

form Solid
color Brown to black

pan-KRAS-IN-5 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0998830 pan-KRAS-IN-5 96.70% 3027172-23-9 5mg $460 2026-06-04 Buy
ChemScene CS-0998830 pan-KRAS-IN-5 96.70% 3027172-23-9 10mg $737 2026-06-04 Buy
ChemScene CS-0998830 pan-KRAS-IN-5 96.70% 3027172-23-9 25mg $1517 2026-06-04 Buy
ChemScene CS-0998830 pan-KRAS-IN-5 96.70% 3027172-23-9 50mg $2437 2026-06-04 Buy
ApexBio Technology BA3144 pan-KRAS-IN-5 3027172-23-9 1mg $153 2026-05-06 Buy
Product number Packaging Price Buy
CS-0998830 5mg $460 Buy
CS-0998830 10mg $737 Buy
CS-0998830 25mg $1517 Buy
CS-0998830 50mg $2437 Buy
BA3144 1mg $153 Buy

pan-KRAS-IN-5 Chemical Properties, Uses, Production

Uses

pan-KRAS-IN-5 (compound 15a) is a pan-KRAS translation inhibitor by targeting 5′-UTR RNA G-quadruplexes (rG4s). pan-KRAS-IN-5 induces cell cycle arrest and promptes apoptosis in KRAS-driven cancer cells[1].

References

[1] Mao-Lin Li, et al. Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5'-UTR RNA G-Quadruplexes. J Med Chem. 2024 Feb 8;67(3):1961-1981. DOI:10.1021/acs.jmedchem.3c01773

pan-KRAS-IN-5 Preparation Products And Raw materials

Raw materials

Preparation Products

pan-KRAS-IN-5 Suppliers

Global Suppliers ( 1)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58

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pan-KRAS-IN-5 Quinolinium, 2-[(1E)-2-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]ethenyl]-6-fluoro-1-methyl-7-[[2-(1-pyrrolidinyl)ethyl]amino]-, iodide (1:1) 3027172-23-9