ChemicalBook >> CAS DataBase List >>SHP2-IN-27

SHP2-IN-27

SHP2-IN-27 structure

CAS No.: 2376012-00-7

Chemical Name:: SHP2-IN-27

Synonyms: SHP2-IN-27;8-Azabicyclo[3.2.1]octan-3-amine, 8-[7-(4-chloro-2-methyl-2H-indazol-5-yl)-5H-pyrrolo[2,3-b]pyrazin-3-yl]-, (3-endo)-

CBNumber:: CB614290891

Molecular Formula:: C21H22ClN7

Molecular Weight:: 407.9

MDL Number:

MOL File:: 2376012-00-7.mol

Last updated:2025-04-18 09:51:18

Request For Quotation

SHP2-IN-27 Properties

Density	1.66±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka	12.23±0.50(predicted)

SHP2-IN-27 Chemical Properties, Uses, Production

Uses

SHP2-IN-27 (compound 28) is an allosteric inhibitor of tyrosine phosphatase SH2[1].

References

[1] Day JEH, et al. Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2). J Med Chem. 2024 Mar 10. DOI:10.1021/acs.jmedchem.3c02118

SHP2-IN-27 Preparation Products And Raw materials

Raw materials

Preparation Products

SHP2-IN-27 Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

2376012-00-7 (SHP2-IN-27) Related Search:

Sodium Stibogluconate SHP836 4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl- 2-Pyrazinemethanol, 6-[(2-amino-3-chloro-4-pyridinyl)thio]-3-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]dec-8-yl]-5-methyl- SHP2-IN-13

L-Lysine, L-asparaginyl-L-histidyl-L-alanyl-L-seryl-L-seryl-L-valyl-L-prolyl-L-arginyl-L-seryl-L-lysyl-L-isoleucyl-L-leucyl-L-threonyl-L-valyl-L-arginyl-L-valyl-L-isoleucyl-L-leucyl-L-alanyl-L-prolyl-L-tryptophyl-L-lysyl-

1of2

SHP2-IN-27 8-Azabicyclo[3.2.1]octan-3-amine, 8-[7-(4-chloro-2-methyl-2H-indazol-5-yl)-5H-pyrrolo[2,3-b]pyrazin-3-yl]-, (3-endo)- 2376012-00-7