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TDI-8304

TDI-8304 structure

CAS No.: 2307262-96-8

Chemical Name:: TDI-8304

Synonyms: TDI-8304;2-Oxa-8,11-diazabicyclo[13.3.1]nonadeca-1(19),15,17-triene-7-carboxamide, N-cyclopentyl-10-[2-(4-morpholinyl)ethyl]-9,12-dioxo-13-(2-oxo-1-pyrrolidinyl)-, (7S,10S,13S)-

CBNumber:: CB614293241

Molecular Formula:: C32H47N5O6

Molecular Weight:: 597.75

MDL Number:

MOL File:: 2307262-96-8.mol

Last updated:2025-05-22 08:02:38

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TDI-8304 Properties

Boiling point	922.619±65.00 °C(Press: 760.00 Torr)(predicted)
Density	1.261±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	13.481±0.70(predicted)

TDI-8304 Chemical Properties, Uses, Production

Uses

TDI-8304, a macrocyclic peptide, is a potent, species selective, and noncovalent Plasmodium falciparum (Pf20S) inhibitor. TDI-8304 shows highly selective for Pf20S over human proteasomes[1].

References

[1] Hao-Chi Hsu, et al. Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors. Nat Commun. 2023 Dec 14;14(1):8302. DOI:10.1038/s41467-023-44077-2

TDI-8304 Preparation Products And Raw materials

Raw materials

Preparation Products

TDI-8304 Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

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TDI-8304 2-Oxa-8,11-diazabicyclo[13.3.1]nonadeca-1(19),15,17-triene-7-carboxamide, N-cyclopentyl-10-[2-(4-morpholinyl)ethyl]-9,12-dioxo-13-(2-oxo-1-pyrrolidinyl)-, (7S,10S,13S)- 2307262-96-8