Thalidomide-PEG2-NH2 hydrochloride
- CAS No.
- 2891597-17-2
- Chemical Name:
- Thalidomide-PEG2-NH2 hydrochloride
- Synonyms
- 4-(H2N-PEG2)-Thalidomide HCl;Thalidomide-PEG2-NH2 hydrochloride;1H-Isoindole-1,3(2H)-dione, 4-[2-(2-aminoethoxy)ethoxy]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)
- CBNumber:
- CB614293610
- Molecular Formula:
- C17H19N3O6.ClH
- Molecular Weight:
- 397.81
- MDL Number:
- MOL File:
- 2891597-17-2.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501 |
Thalidomide-PEG2-NH2 hydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0621394 | Thalidomide-PEG2-NH2 hydrochloride 95.55% | 2891597-17-2 | 25mg | $238 | 2026-06-04 | Buy |
| ChemScene | CS-0621394 | Thalidomide-PEG2-NH2 hydrochloride 95.55% | 2891597-17-2 | 50mg | $390 | 2026-06-04 | Buy |
| ChemScene | CS-0621394 | Thalidomide-PEG2-NH2 hydrochloride 95.55% | 2891597-17-2 | 100mg | $628 | 2026-06-04 | Buy |
| aablocks | AA029W5I | 4-(2-(2-Aminoethoxy)ethoxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride 95% | 2891597-17-2 | 50mg | $179 | 2026-06-02 | Buy |
| aablocks | AA029W5I | 4-(2-(2-Aminoethoxy)ethoxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride 95% | 2891597-17-2 | 100mg | $287 | 2026-06-02 | Buy |
Thalidomide-PEG2-NH2 hydrochloride Chemical Properties, Uses, Production
Uses
Thalidomide-PEG2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate (E3 Ligase Ligand-Linker Conjugates) that incorporates the Thalidomide (Thalidomide (HY-14658)) based cereblon ligand and a linker used in PROTAC technology[1].
IC 50
Cereblon
References
[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine. Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-996. DOI:10.1016/j.ccell.2020.07.008
Thalidomide-PEG2-NH2 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Thalidomide-PEG2-NH2 hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| Shandong utilizing biological technology co., LTD | 18669728830 15966937598 | 3407650895@qq.com | China | 5165 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| Affinity（Wuhan）Ltd. | 15841022315 | sales@affinitytech.cn | China | 2980 | 58 |
| Jinan Demai Medical Technology Co., LTD | 18669728830 15806766175 | 865681093@qq.com | China | 4996 | 58 |
| Shanghai Haohong Scientific Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39319 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 4008675858 | sales1@amateksci.com | China | 8528 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd | 025-5885952 15955137747 | sales@aikonchem.com | China | 8012 | 58 |
| Shanghai Yanfen Biochemical Technology Co.,LTD | 17721070236 | yanfen2026@126.com | China | 2198 | 58 |
| Affinity Linkers Ltd. | 15841022315 15841022315 | sales@affinitytech.cn | China | 7039 | 58 |
