ChemicalBook >> CAS DataBase List >>3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide structure

CAS No.: 199666-03-0

Chemical Name:: 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide

Synonyms: CS-1828;R061-8048;Ro 61-8048, >=98%;Ro 61-8048 ，S8172;Ro 61-8048 >=98% (HPLC);Ro 61-8048 (Ro-61-8048);Ro 61-8048, 10 mM in DMSO;KMO Inhibitor I, Ro 61-8048;Ro 61-8048, kynurenine 3-monooxygenase (KMO) inhibitor;KMO Inhibitor I, Ro 61-8048 - CAS 199666-03-0 - Calbiochem

CBNumber:: CB61458468

Molecular Formula:: C17H15N3O6S2

Molecular Weight:: 421.45

MDL Number:: MFCD11040807

MOL File:: 199666-03-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-20 23:19:27

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3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Properties

Melting point	185℃
Boiling point	627.4±65.0 °C(Predicted)
Density	1.471±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.	2-8°C
solubility	DMSO: ≥15mg/mL
pka	6.29±0.10(Predicted)
form	Yellow solid
color	faint yellow to yellow
InChI	1S/C17H15N3O6S2/c1-25-15-7-6-13(9-16(15)26-2)28(23,24)19-17-18-14(10-27-17)11-4-3-5-12(8-11)20(21)22/h3-10H,1-2H3,(H,18,19)
InChIKey	NDPBMCKQJOZAQX-UHFFFAOYSA-N
SMILES	COc1ccc(cc1OC)S(=O)(=O)Nc2nc(cs2)-c3cccc(c3)[N+]([O-])=O
UNSPSC Code	12352200
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H319

Precautionary statements

P305+P351+P338

Hazard Codes

Risk Statements

25-36

Safety Statements

26-45

WGK Germany

Storage Class

11 - Combustible Solids

NFPA 704

	0
2		0

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide price More Price(57)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML0233	Ro 61-8048 ≥98% (HPLC)	199666-03-0	5mg	$146	2026-04-30	Buy
Sigma-Aldrich	420360-M	KMO Inhibitor I, Ro 61-8048 - CAS 199666-03-0 - Calbiochem	199666-03-0	10mg	$155	2026-04-30	Buy
Sigma-Aldrich	420360-M	KMO Inhibitor I, Ro 61-8048 The KMO Inhibitor I, Ro 61-8048, also referenced under CAS 199666-03-0, controls the biological activity of KMO. This small molecule/inhibitor is primarily used for Neuroscience applications.	199666-03-0	1 unit	$145	2025-07-31	Buy
Sigma-Aldrich	420360-M	KMO Inhibitor I, Ro 61-8048	199666-03-0	10mg-m	$135	2021-12-16	Buy
Cayman Chemical	15199	Ro 61-8048 ≥98%	199666-03-0	5mg	$90	2026-04-30	Buy

Product number	Packaging	Price	Buy
SML0233	5mg	$146	Buy
420360-M	10mg	$155	Buy
420360-M	1 unit	$145	Buy
420360-M	10mg-m	$135	Buy
15199	5mg	$90	Buy

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Chemical Properties, Uses, Production

Uses

Ro 61-8048 is a potent and competitive kynurenine 3-monooxygenase (KMO) inhibitor.

Definition

ChEBI: Ro 61-8048 is a C-nitro compound.

Biological Activity

Potent and competitive kynurenine 3-hydroxylase inhibitor (K i = 4.8 nM, IC 50 = 37 nM). Increases kynurenic acid levels to concentrations that antagonize the glycine site of NMDA receptors. Brain penetrant and exhibits antidystonic, anticonvulsant and neuroprotective activities.

Biochem/physiol Actions

Ro 61-8048 is an inhibitor of kynurenine 3-monooxygenase (KMO) that increases kynurenic acid levels and reduces extracellular glutamate in the brain.

storage

+4°C

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Suppliers

Global Suppliers ( 131)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2915	55
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
Chembest Research Laboratories Limited	021-20908456	sales@BioChemBest.com	China	5996	61
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64
Dalian Meilun Biotech Co., Ltd.	0411-62910999 13889544652	sales@meilune.com	China	4765	58
Shanghai T&W Pharmaceutical Co., Ltd.	+86 21 61551611		China	9874	58
Haoyuan Chemexpress Co., Ltd.	021-58950125	info@chemexpress.com	China	7545	61
shanghai cooperpharm co.,LTD .	+86-021-58975553	sales@cooperpharm.com	China	1210	56
Nanjing Dulai Biotechnology Co., Ltd.	025-84699383-8003;025-846993838003-8003 18013301590	njduly@126.com	China	3293	55
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60

Supplier	Advantage
Shanghai Boyle Chemical Co., Ltd.	55
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Chembest Research Laboratories Limited	61
Nanjing Chemlin Chemical Co., Ltd	64
Dalian Meilun Biotech Co., Ltd.	58
Shanghai T&W Pharmaceutical Co., Ltd.	58
Haoyuan Chemexpress Co., Ltd.	61
shanghai cooperpharm co.,LTD .	56
Nanjing Dulai Biotechnology Co., Ltd.	55
Bide Pharmatech Ltd.	60

View Latest Price from 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-20	Ro 61-8048 199666-03-0	$33.00-70.00		99.87%	10g	TargetMol Chemicals Inc.
	2019-09-05	3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide 199666-03-0	$1.00	1ASSAYS	98%	10kg	Career Henan Chemical Co

Ro 61-8048
199666-03-0
$33.00-70.00
99.87%
TargetMol Chemicals Inc.

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
199666-03-0
$1.00
98%
Career Henan Chemical Co

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Spectrum

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide(199666-03-0)¹HNMR

199666-03-0 (3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide) Related Search:

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ROC-325 RO2959 Hydrochloride

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Ro 61-8048, >=98% RO61-80483,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)Benzenesulfonamide 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide RO61-8048 RO 61-8048 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide KMO Inhibitor I, Ro 61-8048 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide 3,4-diMethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonaMide CS-1828 KMO Inhibitor I, Ro 61-8048 - CAS 199666-03-0 - Calbiochem R061-8048 3,4-Dimethoxy-N-4-(3-nitro-phenyl)-thiazol-2-yl-benzenesulfomide Benzenesulfonamide, 3,4-dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]- Ro 61-8048 >=98% (HPLC) NMDA,Ro 61 8048,inhibit,Ro 61-8048,dystonia,Inhibitor,hydroxylase,Ro 618048,kynurenine 3,4-dimethoxy 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Ro 61-8048, kynurenine 3-monooxygenase (KMO) inhibitor Ro 61-8048, 10 mM in DMSO Ro 61-8048 ，S8172 Ro 61-8048 (Ro-61-8048) 199666-03-0 C17H15N3O6S2 Inhibitors