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N-METHYLNICOTINAMIDE

CAS No.
114-33-0
Chemical Name:
N-METHYLNICOTINAMIDE
Synonyms
3-Pyridinecarboxamide, N-methyl-;Methylnicotinamide;N-METHYLNICOTINAMIDE;N'-METHYLNICOTINAMIDE;METHYLNICOTINAMIDE, N-;N-Methylnicotinamide>Nicotinamide Impurity 7;N-Methylnicotinamide,98%;Nicotinamide Impurity 121;Nicotinic Acid Methylamide
CBNumber:
CB6151285
Molecular Formula:
C7H8N2O
Molecular Weight:
136.15
MDL Number:
MFCD00006384
MOL File:
114-33-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-20 23:19:27
Product description Number Pack Size Price
N-Methylnicotinamide >98.0%(GC)(T) M0374 10g $82
N-Methylnicotinamide >98.0%(GC)(T) M0374 25g $134
N-Methylnicotinamide ≥98% 21850 5g $54
N-Methylnicotinamide ≥98% 21850 10g $85
N-Methylnicotinamide ≥98% 21850 25g $158

N-METHYLNICOTINAMIDE Properties

Melting point 102-105 °C(lit.)
Boiling point 250.42°C (rough estimate)
Density 1.1778 (rough estimate)
refractive index 1.5769 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 13.97±0.46(Predicted)
color White to Off-White
InChI InChI=1S/C7H8N2O/c1-8-7(10)6-3-2-4-9-5-6/h2-5H,1H3,(H,8,10)
InChIKey ZYVXHFWBYUDDBM-UHFFFAOYSA-N
SMILES C1=NC=CC=C1C(NC)=O
CAS DataBase Reference 114-33-0(CAS DataBase Reference)
FDA UNII X3I82S5L8I

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  2933.39.9200
NFPA 704
0
2 0

N-METHYLNICOTINAMIDE price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical M0374 N-Methylnicotinamide >98.0%(GC)(T) 114-33-0 10g $82 2026-04-30 Buy
TCI Chemical M0374 N-Methylnicotinamide >98.0%(GC)(T) 114-33-0 25g $134 2026-04-30 Buy
Cayman Chemical 21850 N-Methylnicotinamide ≥98% 114-33-0 5g $54 2026-04-30 Buy
Cayman Chemical 21850 N-Methylnicotinamide ≥98% 114-33-0 10g $85 2026-04-30 Buy
Cayman Chemical 21850 N-Methylnicotinamide ≥98% 114-33-0 25g $158 2026-04-30 Buy
Product number Packaging Price Buy
M0374 10g $82 Buy
M0374 25g $134 Buy
21850 5g $54 Buy
21850 10g $85 Buy
21850 25g $158 Buy

N-METHYLNICOTINAMIDE Chemical Properties,Uses,Production

Chemical Properties

white to light yellow-beige crystalline powder

Uses

N-Methylnicotinamide is a metabolite of Nicotinamide (N407750), which is a water-soluble vitamin B, incorporated within nicotinamide cofactors such as NADH and NADPH. N-Methylnicotinamide is commonly found in the human urine and is used as a biomarker to study diseases such as liver cirrhosis and type 2 diabetes.

Definition

ChEBI: A pyridinecarboxamide that is nicotinamide in which one of the amide hydrogens is substituted by a methyl group.

in vivo

N-Methylnicotinamide (3-30 mg/kg, i.v., 10 min before the induction of arterial thrombosis) decreases the arterial thrombus weight, collagen induced platelet aggregation and decreases PAI-1 antigen and activity in plasma without changing t-PA activity in 2K-1C hypertensive rats[1].
N-Methylnicotinamide (30-300 mg/kg, mixed in the diet, daily for 31 days) significantly increases the liver weight, the content of NAD and total nicotinamide in liver and the content of NAD in blood in rats[3].

Animal Model:2K-1C hypertensive rats[1]
Dosage:3-30 mg/kg
Administration:i.v., 10 min before the induction of arterial thrombosis
Result:Resulted in a dose-dependent decrease of arterial thrombus weight, decreased PAI-1 antigen and activity in plasma in dose-dependent manner, whereas it did not change t-PA activity, decreased collagen induced platelet aggregation in dose-dependent manner.
Animal Model:Weanling male rats[3]
Dosage:30-300 mg/kg
Administration:mixed in the diet, daily for 31 days
Result:Significantly increased the liver weight, statistically significantly the content of NAD and total nicotinamide in liver and the content of NAD in blood in rats.

IC 50

Microbial Metabolite; Human Endogenous Metabolite

N-METHYLNICOTINAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

N-METHYLNICOTINAMIDE Suppliers

Global( 169)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED
sales@conier.com China 49906 58
career henan chemical co
+86-0371-86658258 factory@coreychem.com China 29780 58
Fuxin Pharmaceutical
+86-021-021-50872116 contact@fuxinpharm.com China 9976 58
TargetMol Chemicals Inc.
+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Hubei Ipure Biology Co., Ltd
+8618062405514 ada@ipurechemical.com China 10224 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6290 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-81139210 +86-17392587031 1059@dideu.com China 9984 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 17705817739 info@dycnchem.com China 52693 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 38999 58
PT CHEM GROUP LIMITED
+86-85511178; +86-85511178 peter68@ptchemgroup.com China 35405 58

View Lastest Price from N-METHYLNICOTINAMIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Methylnicotinamide pictures 2026-08-08 N-Methylnicotinamide
114-33-0
$35.00 99.44% 10g TargetMol Chemicals Inc.
N-METHYLNICOTINAMIDE pictures 2020-02-11 N-METHYLNICOTINAMIDE
114-33-0
$9.80 1g >98% 20 tons Career Henan Chemical Co
N'-METHYLNICOTINAMIDE N-METHYLNICOTINAMIDE METHYLNICOTINAMIDE, N- Methylnicotinamide N-Methyl-3-pyridinecarboxamide. 3-Pyridinecarboxamide,N-methyl-(9CI) N-Methylnicotinamide, GC 98% N-Methylpyridine-3-carboxamide N-Methylnicotinamide,98% N-Methylnicotinamide N-Methylnicotinamide> Nicotinic Acid Methylamide Sorafenib tosylate Impurity 4 Nicotinamide Impurity 7 3-(Methylcarbamoyl)pyridine 3-(Methylcarbamoyl)pyridine , N-Methylnicotinamide Nicotinamide Impurity 121 N-Methylnicotinamide, 10 mM in DMSO 3-Pyridinecarboxamide, N-methyl- 114-33-0 AMIDE