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Thionicotinamide adenine dinucleotide

Thionicotinamide adenine dinucleotide structure

CAS No.: 4090-29-3

Chemical Name:: Thionicotinamide adenine dinucleotide

Synonyms: THIO-NAD;S-NAD;Thio-Coenzyme;Thio-NAD >95%;Thio-NAD/S-NAD;S-NAD/ Thio-NAD;Thionicotinamide-NAD;THIONICOTINAMIDE-DPN;Nicotinamide Impurity 1;Thiooxidative coenzyme I

CBNumber:: CB1208182

Molecular Formula:: C21H27N7O13P2S

Molecular Weight:: 679.49

MDL Number:: MFCD00079609

MOL File:: 4090-29-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-07 16:58:08

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Thionicotinamide adenine dinucleotide Properties

storage temp.	-20°C
solubility	PBS (pH 7.2): 10 mg/ml
form	powder to crystal
color	Light orange to Yellow to Green
InChIKey	DQRRIGAXTAXHLR-NNYOXOHSSA-N
SMILES	O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP([O-])(=O)OC[C@@H]2[C@H]([C@@H](O)[C@H]([N+]3=CC=CC(C(=S)N)=C3)O2)O)O[C@H]1N1C=NC2C(=NC=NC1=2)N)O \|&1:1,2,3,15,16,17,19,32,r\|
CAS DataBase Reference	4090-29-3
UNSPSC Code	41106305
NACRES	NA.51

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302+H312+H332-H315-H319-H335
Precautionary statements	P280-P271
Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38
Safety Statements	26-36
WGK Germany	-
HS Code	29349990
Storage Class	11 - Combustible Solids

Thionicotinamide adenine dinucleotide price More Price(33)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	T7375	Thionicotinamide adenine dinucleotide ≥90%	4090-29-3	25mg	$206	2026-04-30	Buy
Sigma-Aldrich	T7375	Thionicotinamide adenine dinucleotide ≥90%	4090-29-3	100mg	$588	2026-04-30	Buy
TCI Chemical	T2979	Thionicotinamide Adenine Dinucleotide oxidized form [for Biochemical Research] >95.0%(HPLC)	4090-29-3	100mg	$310	2026-04-30	Buy
Cayman Chemical	36466	Thio-NAD ≥95%	4090-29-3	25mg	$79	2026-04-30	Buy
Cayman Chemical	36466	Thio-NAD ≥95%	4090-29-3	50mg	$148	2026-04-30	Buy

Product number	Packaging	Price	Buy
T7375	25mg	$206	Buy
T7375	100mg	$588	Buy
T2979	100mg	$310	Buy
36466	25mg	$79	Buy
36466	50mg	$148	Buy

Thionicotinamide adenine dinucleotide Chemical Properties, Uses, Production

Description

Thionicotinamide adenine dinucleotide is an analog of NAD. Use of Thio-NAD instead of NAD as a substrate for NAD(+)-consuming enzymes is more advantageous since the reduced form of Thio-NAD exhibits a substantial increase in absorbance at 405 nM, the most commonly available wavelength on microplate readers.

Chemical Properties

Light yellow powder

Uses

Thionicotinamide adenine dinucleotide has been used as a substrate analog in S-adenosyl-l-homocysteine (AdoHcy) hydrolases (SAHH) inhibition assay and in NAD+ glycohydrolase activity.

Application

Thionicotinamide adenine dinucleotide (thio-NAD) is a NAD derivative used in the determination of Carnitine by an enzymic cycling method with carnitine dehydrogenase.

Biochem/physiol Actions

Thionicotinamide adenine dinucleotide (sNAD) is an analog of coenzyme nicotinamide adenine dinucleotide (NAD) and NADH. sNAD is a potential inhibitor of NAD+ kinase. NAD+ kinase modulates NAD levels, contributing to cytotoxicity in cancer cells.

storage

Transport product sealed, dry, and protected from light at ambient temperature. Store product dry and protected from light. For long term storage keep below -20℃.

References

[1] SATOSHI WATABE. Ultrasensitive enzyme-linked immunosorbent assay (ELISA) of proteins by combination with the thio-NAD cycling method.[J]. Biophysics (Nagoya-shi, Japan), 2014, 10: 49-54. DOI: 10.2142/biophysics.10.49
[2] YUTA KYOSEI. Proposal of De Novo Antigen Test for COVID-19: Ultrasensitive Detection of Spike Proteins of SARS-CoV-2.[C]//10 8. 2020. DOI: 10.3390/diagnostics10080594
[3] WEN-HUNG WANG. A novel, rapid (within hours) culture-free diagnostic method for detecting live Mycobacterium tuberculosis with high sensitivity.[J]. EBioMedicine, 2020, 60: 103007. DOI: 10.1016/j.ebiom.2020.103007

Thionicotinamide adenine dinucleotide Preparation Products And Raw materials

Raw materials

Preparation Products

Thionicotinamide adenine dinucleotide Suppliers

Global Suppliers ( 201)

Supplier	Tel	Email	Country	ProdList	Advantage
Bontac Bio-engineering (Shenzhen) Co., Ltd.	+86-0755-27212902 18025386762	marketing@bontac-bio.com	China	25	60
Jiangsu Enzymatic Co.,Ltd.	0512-58587898 13812862084	AnnaXu@rexinbio.com	China	52	58
Hzymes Biotechnology Co. LTD	400-8085320 16621234168	hhxm-info@hzymes.com	China	28	58
Maintain Biotech Co., Ltd.	755-89664337 19125366885	sales@maintain-bio.com	China	67	58
Syncozymes (Shanghai) Co.,Ltd.	021-68187180 13681683526	lchen@syncozymes.com	China	412	55
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64
Hunan Hui Bai Shi Biotechnology Co., Ltd.	0731-85526065 13308475853	ivy@hnhbsj.com	China	7236	62

Supplier	Advantage
Bontac Bio-engineering (Shenzhen) Co., Ltd.	60
Jiangsu Enzymatic Co.,Ltd.	58
Hzymes Biotechnology Co. LTD	58
Maintain Biotech Co., Ltd.	58
Syncozymes (Shanghai) Co.,Ltd.	55
J & K SCIENTIFIC LTD.	76
TCI (Shanghai) Development Co., Ltd.	81
Adamas Reagent, Ltd.	59
Nanjing Chemlin Chemical Co., Ltd	64
Hunan Hui Bai Shi Biotechnology Co., Ltd.	62

View Latest Price from Thionicotinamide adenine dinucleotide manufacturers

Update time	Product	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-15	Thio-NAD 4090-29-3	1g	99.0%	10kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-09-14	Thionicotinamide adenine dinucleotide 4090-29-3	1G	0.95	10000 G	Nanjing pathgene biotech co .,ltd
2026-08-09	Thionicotinamide adenine dinucleotide 4090-29-3		95%	20tons	Chongqing Zhihe Biopharmaceutical Co., Ltd.

Thio-NAD
4090-29-3
$0.00
99.0%
WUHAN FORTUNA CHEMICAL CO., LTD

Thionicotinamide adenine dinucleotide
4090-29-3
0.95
Nanjing pathgene biotech co .,ltd

Thionicotinamide adenine dinucleotide
4090-29-3
95%
Chongqing Zhihe Biopharmaceutical Co., Ltd.

4090-29-3 (Thionicotinamide adenine dinucleotide) Related Search:

N-Ethylnicotinamide N-Methylnicotinamide 6-Methylnicotinamide Nicotinamide riboside chloride Nicotinamide-N-oxide

Ethionamide Nicotinamide Nicotinamide riboside Triphosphopyridine nucleotide Nadph tetrasodium salt

NADP sodium salt NADH, disodium salt NADH Inhibitor Nicotinamide hypoxanthine dinucleotide phosphate reduced tetrasodium salt NADP, Disodium Salt

β-Nicotinamide adenine dinucleotide β-Nicotinamide Mononucleotide N,N'-Dipyridin-3-ylurea

1of4

THIONICOTINAMIDE ADENINE DINUCLEOTIDE THIONICOTINAMIDE-DPN adenosine 5'-(trihydrogen diphosphate), 5'->5'-ester with 3-(aminothioxomethyl)-1-beta-D-ribofuranosylpyridinium--ate Thionicotinamide-NAD beta-Thionicotinamide adenine dinucleotide, oxidised form 92+% 3-Thiocarbamoylpyridine adenine dinucleotide 3-Thionicotinamide adenine dinucleotide Thino-Nicotinamide Adenine Dinuclotide Adenosine5'-(trihydrogen diphosphate), P'5'-ester with 3-(aminothioxomethyl)-1-b-D-ribofuranosylpyridinium, inner salt Thionicotinamide Adenine Dinucleotide(THIO-NAD) ThionicotinaMide Adenine Dinucleotide oxidized forM [for BiocheMical Research] 5'-ester with 3-(aMinothioxoMethyl)-1-b-D-ribofuranosylpyridiniuM, inner salt Adenosine5'-(trihydrogen diphosphate), P'® Thionicotinamide-DPN oxidized form β-ThionicotinaMide adenine dinucleotide, Oxidized forM β-Thionicotinamide adenine dinucleotide, 90%, Oxidized form Thio-Nicotinamide-Adenine Dinucleotide, Oxidized (Thio-NAD). Thio-NAD/S-NAD Thio-Nicotinamide Adenine Dinuclotide Thio-NAD Thionicotinamide adenine dinucleotide Thiooxidative coenzyme I Thionicotinamide Adenine Dinucleotide (Thio-NAD) extrapure, 90% Nicotinamide Impurity 1 Thio-Coenzyme Thio-NAD >95% S-NAD S-NAD/ Thio-NAD 1-((2R,3R,4S,5R)-5-((((((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)oxidophosphoryl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-3-carbamothioylpyridin-1-ium Thio oxidized coenzyme I/thio coenzyme/reduced nicotinamide hypoxanthine dinucleotide Protirelin Impurity 3 (Protirelin EP Impurity C) Oxidized thio coenzyme I THIONICOTINAMIDE ADENINE DINUCLEOTIDE 98%with hydrate one Thionicotinamide adenine dinucleotide【T7375】 beta-Thionicotinamide adenine dinucleotide, oxidised form 7H-Purin-6-amine, 7-(2-deoxy-β-D-erythro-pentofuranosyl)- (9CI, ACI) THIO-NAD 4090-29-3 C21H27N7O13P2S C21H27N7O13SP2 BioChemical Biochemicals and Reagents Cofactors Enzymes, Inhibitors, and Substrates Oxidation-Reduction nucleoside