CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID
![CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID Structure](CAS/GIF/110347-85-8.gif)
- CAS No.
- 110347-85-8
- Chemical Name:
- CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID
- Synonyms
- Selfotel;CGS 19755;CPDD 0027;LY-272541;Valine Impurity 11;Argatroban Impurity 122;CGS-19755 \ POTENT COMPETITIVE NMDA RECE;4-(phosphonomethyl)-2-piperidinecarboxylic acid;cis-4-[Phosphomethyl]-piperidine-2-carboxylicacid;CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID
- CBNumber:
- CB6154963
- Molecular Formula:
- C7H14NO5P
- Molecular Weight:
- 223.16
- MDL Number:
- MFCD06795863
- MOL File:
- 110347-85-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| CGS19755 | 1241 | 50 | $685 |
| CGS19755 | 1241 | 10 | $163 |
| CGS 19755 | 254949 | 10mg | $466 |
| CGS19755 | C291808 | 100mg | $1470 |
| CGS19755 | B6652 | 10mg | $314 |
| Melting point | 290-292 °C |
|---|---|
| Boiling point | 508.6±60.0 °C(Predicted) |
| Density | 1.440±0.06 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | H2O: soluble |
| form | solid |
| pka | 2.29±0.10(Predicted) |
| color | white |
| Water Solubility | Soluble to 25 mM in water |
| FDA UNII | 4VGJ4A41L2 |
CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 1241 | CGS19755 | 110347-85-8 | 50 | $685 | 2021-12-16 | Buy |
| Tocris | 1241 | CGS19755 | 110347-85-8 | 10 | $163 | 2021-12-16 | Buy |
| Usbiological | 254949 | CGS 19755 | 110347-85-8 | 10mg | $466 | 2021-12-16 | Buy |
| TRC | C291808 | CGS19755 | 110347-85-8 | 100mg | $1470 | 2021-12-16 | Buy |
| ApexBio Technology | B6652 | CGS19755 | 110347-85-8 | 10mg | $314 | 2021-12-16 | Buy |
CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID Chemical Properties,Uses,Production
Uses
CGS 19755 is a potent and competitive NMDA antagonist.
Definition
ChEBI: Selfotel is a non-proteinogenic alpha-amino acid.
Biological Activity
Potent, competitive NMDA receptor antagonist. Anticonvulsant and neuroprotective. Also available as part of the Mixed NMDA Receptor Tocriset™ .
in vivo
Selfotel (CGS 19755) administered p.o. by gavage has little or no effect in these test procedures. In an experimental model of anxiety in rats[1].
Selfotel (CGS 19755) significantly increases conflict responding within a relatively narrow dose range (minimum effective dose, 1.73 mg/kg i.p.)[1].
Selfotel (CGS 19755) blocks the harmaline-induced increase in cerebellar cyclic GMP levels at a dose of 4 mg/kg i.p. with duration of action exceeding 2 hr[2].
Selfotel (CGS 19755) inhibits convulsions elicited by maximal electroshock in rat (ED50 = 3.8 mg/kg i.p. 1 hr after administration) and in mouse (ED50 = 2.0 mg/kg i.p. 0.5 hr after administration)[2].
storage
Store at RT
CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32469 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13913916777 | info@chemlin.com.cn | China | 16024 | 64 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Wuxi AppTec | 022-59987777 13552403979 | jia_guoqiang@wuxiapptec.com | China | 22345 | 58 |
| Aikon International Limited | 025-58859352 19370895928 | sales01@aikonchem.com | China | 15082 | 58 |
| Jinan Yaoyan Pharmaceutical Co., Ltd. | jnyaoyan@163.com | China | 3069 | 58 |
