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ChemicalBook >> CAS DataBase List >>3,4,5,6-Tetrafluorophthalonitrile

3,4,5,6-Tetrafluorophthalonitrile

3,4,5,6-Tetrafluorophthalonitrile Structure
3,4,5,6-Tetrafluorophthalonitrile structure
CAS No.
1835-65-0
Chemical Name:
3,4,5,6-Tetrafluorophthalonitrile
Synonyms
TFPN;TETRAFLUOROPHTHALONITRILE;3,4,5,6-Tetrafluoro-1,2-benzenedicarbonitrile;Tetrafl;onitriL;uorophthaL;Tetrafluorophthalonitrile98%;Tetrafluoro-o-phthalonitrile;Tetrafluorophthalonitrile 98%;Tetrafluorophthalonitrile ,99%
CBNumber:
CB6202574
Molecular Formula:
C8F4N2
Molecular Weight:
200.09
MDL Number:
MFCD00001774
MOL File:
1835-65-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:43:46
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3,4,5,6-Tetrafluorophthalonitrile Properties

Melting point 81-86 °C(lit.)
Boiling point 274.2±40.0 °C(Predicted)
Density 1.54±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol,Acetone,Ethanol
form powder to crystal
color White to Almost white
InChI InChI=1S/C8F4N2/c9-5-3(1-13)4(2-14)6(10)8(12)7(5)11
InChIKey OFLRJMBSWDXSPG-UHFFFAOYSA-N
SMILES C1(C#N)=C(F)C(F)=C(F)C(F)=C1C#N
CAS DataBase Reference 1835-65-0(CAS DataBase Reference)
NIST Chemistry Reference Tetrafluorophthalonitrile(1835-65-0)
EPA Substance Registry System Tetrafluorophthalonitrile (1835-65-0)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36
RIDADR  3439
WGK Germany  3
Hazard Note  Irritant/Lachrymator
HazardClass  6.1(b)
PackingGroup  III
HS Code  29269090
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

3,4,5,6-Tetrafluorophthalonitrile price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 196819 Tetrafluorophthalonitrile 95% 1835-65-0 1g $31.6 2026-04-30 Buy
TCI Chemical T1402 Tetrafluorophthalonitrile >98.0%(GC) 1835-65-0 5g $43 2026-04-30 Buy
TCI Chemical T1402 Tetrafluorophthalonitrile >98.0%(GC) 1835-65-0 25g $140 2026-04-30 Buy
AstaTech 60628 1,2-DICYANO-3,4,5,6-TETRAFLUOROBENZENE 97% 1835-65-0 25G $26 2026-04-30 Buy
AstaTech 60628 1,2-DICYANO-3,4,5,6-TETRAFLUOROBENZENE 97% 1835-65-0 100G $84 2026-04-30 Buy
Product number Packaging Price Buy
196819 1g $31.6 Buy
T1402 5g $43 Buy
T1402 25g $140 Buy
60628 25G $26 Buy
60628 100G $84 Buy

3,4,5,6-Tetrafluorophthalonitrile Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

Tetrafluorophthalonitrile was used in the synthesis of dichloro-subphthalocyanine dimers.

General Description

Tetrafluorophthalonitrile reacts with:

  • copper, copper (I) chloride or copper (II) chloride to yield copper (II) hexadecafluorophthalocyanine
  • potassium salt of 2-hydroxyhexafluoro-2-propylbenzene to yield 2-phenyl-2-(3,4-dicyano- trifluorophenoxy) hexafluoropropane
  • dipotassium salt of 1,3-bis(2-hdroxyhexafluoro-2- propyl) benzene to yield fluorinated phthalonitrile resins

Synthesis

Sulfolane

126-33-0

3,4,5,6-Tetrachlorophthalonitrile

1953-99-7

3,4,5,6-Tetrafluorophthalonitrile

1835-65-0

Example A Synthesis of 3,4,5,6-tetrafluorophthalonitrile: Anhydrous potassium fluoride (11.0 kg) was added to a 50 gallon stainless steel reactor. The salt was dried at 115°-138°C for 48 hours under 28 inches of vacuum. After the salt was cooled to 100°C, cyclobutanesulfone (19 liters) and tetrachlorophthalonitrile (4.74 kg) were added sequentially. The mixture was heated to 156°C within 30 minutes with stirring, followed by continued heating at 135°-162°C for 2.5 hours with vigorous stirring. Upon completion of the reaction, the mixture was cooled to 31°C (taking 15 minutes) and ice (69 kg) and softened water (119 liters) were added. After stirring the resulting mixture for 1.5 hours, the crude product was collected by centrifugation and washed with softened water (120 liters). The crude product was retransferred to a 50-gallon stainless steel still with deionized water (100 liters). Steam distillation was performed until 80 liters of distillate were collected. The distillate was cooled to 0°-5°C and the product was collected by centrifugation. The crystals were washed with softened water (2 x 90 l) to give 2.82 kg of wet product (LOD 6.4%; calculated yield: 74%). A small amount of the sample was vacuum dried at room temperature for two days and the melting point was measured to be 81°-83°C.

References

[1] Patent: US4782180, 1988, A

3,4,5,6-Tetrafluorophthalonitrile synthesis

126-33-0
1953-99-7
1835-65-0
Synthesis of 3,4,5,6-Tetrafluorophthalonitrile from Sulfolane and 3,4,5,6-Tetrachlorophthalonitrile

3,4,5,6-Tetrafluorophthalonitrile Preparation Products And Raw materials

Raw materials

1,2-Benzenedicarbonitrile, 4-chloro-3,5,6-trifluoro- 1,2-Dibromotetrafluorobenzene 3,4,5,6-Tetrachlorophthalonitrile Potassium fluoride Water
Sulfolane Copper(I) Cyanide

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Preparation Products

Benzoyl fluoride

3,4,5,6-Tetrafluorophthalonitrile Suppliers

Global( 314)Suppliers
Supplier Tel Email Country ProdList Advantage
Xi'an Huarui Zhiyuan Biotechnology Co., Ltd. 18014474522 3487723181@qq.com China 1166 58
Shandong AiSimankman 13698626386 13698626386 2559863971@qq.com China 462 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Ark Pharm, Inc. 847-367-3680 sales@arkpharminc.com United States 1669 56
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2776 65
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Supplier Advantage
Xi'an Huarui Zhiyuan Biotechnology Co., Ltd. 58
Shandong AiSimankman 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
TCI (Shanghai) Development Co., Ltd. 81
ShangHai DEMO Chemical Co.,Ltd 57
Ark Pharm, Inc. 56
Energy Chemical 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 65
Capot Chemical Co., Ltd 66

View Lastest Price from 3,4,5,6-Tetrafluorophthalonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,4,5,6-Tetrafluorophthalonitrile pictures 2026-09-02 3,4,5,6-Tetrafluorophthalonitrile
1835-65-0
 $1.20-36.00 1kg 99% Henan Fengda Chemical Co., Ltd
3,4,5,6-Tetrafluorophthalonitrile pictures 2026-06-30 3,4,5,6-Tetrafluorophthalonitrile
1835-65-0
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
3,4,5,6-Tetrafluorophthalonitrile pictures 2025-06-27 3,4,5,6-Tetrafluorophthalonitrile
1835-65-0
 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd

3,4,5,6-Tetrafluorophthalonitrile Spectrum

3,4,5,6-Tetrafluorophthalonitrile(1835-65-0)MS3,4,5,6-Tetrafluorophthalonitrile(1835-65-0)1HNMR3,4,5,6-Tetrafluorophthalonitrile(1835-65-0)13CNMR3,4,5,6-Tetrafluorophthalonitrile(1835-65-0)IR13,4,5,6-Tetrafluorophthalonitrile(1835-65-0)IR23,4,5,6-Tetrafluorophthalonitrile(1835-65-0)Raman

1835-65-0(3,4,5,6-Tetrafluorophthalonitrile)Related Search:

o-Phenylenediamine o-Phthalaldehyde 1,2-Dimethoxybenzene Potassium hydrogen phthalate Dibutyl phthalate
Phthalonitrile 3-Fluorophthalic acid 3,4,5,6-Tetrachlorophthalonitrile 2-Cyanophenol Bis(2-ethylhexyl) phthalate
Dimethyl phthalate 4-Aminophthalonitrile Phthalic acid 2,4,5,6-Tetrafluoroisophthalonitrile Phthalic anhydride
Phthalimide Phthalamide Phthaloyl dichloride

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3,4,5,6-tetrafluorobenzene-1,2-dicarbonitrile Tetrafluorophthalonitrile 98% Tetrafluorophthalonitrile98% 3,4,5,6-Tetrafluorophthalodinitrile 3,4,5,6-TETRAFLUOROPHTHALONITRILE 98% 1,2-DICYANO-3,4,5,6-TETRAFLUOROBENZENE 3,4,5,6-TETRAFLUOROPHTHALONITRILE 1,2-Benzenedicarbonitrile, 3,4,5,6-tetrafluoro- 1,2-Dicyano-3,4,5,6-tetrafluorobenzene, 3,4,5,6-Tetrafluoro-1,2-benzenedicarbonitrile 3,4,5,6-Tetrafluoro-1,2-benzenedicarbonitrile Tetrafluorophthalonitrile ,99% Tetrafl 3,4,5,6-PTFEphthalicnitriletwo 3,4,5,6-tetrafluoro phthalonitrile (tetrafluoro phthalonitrile) 3,4,5,6-Tetrafluorbenzol-1,2-dicarbonitril onitriL uorophthaL Tetrafluorophthalonitrile, 99%, for synthesis 1835-65-0 3,4,5,6-Tetrafluorophthalonitrile Tetrafluoro-o-phthalonitrile 3,4,5,6-Tetraflourophtalonitrile Sitagliptin Phosphate Impurity 319 TETRAFLUOROPHTHALONITRILE TFPN 1835-65-0 C6F4CN2 Building Blocks C8 to C9 Cyanides/Nitriles Organic Building Blocks Nitrogen Compounds Phthalonitriles (Building Blocks for Phthalocyanines) Phthalonitriles & Naphthalonitriles Phthalonitriles (Building Blocks for Phthalocyanines) pharmacetical Functional Materials Phthalonitriles & Naphthalonitriles